Genomewide linkage in a large Dutch family with intracranial aneurysms: replication of 2 loci for intracranial aneurysms to chromosome 1p36.11-p36.13 and Xp22.2-p22.32

Autor: Cisca Wijmenga, Frank Baas, Yvo B.W.E.M. Roos, Andries Westerveld, Marcel Wolfs, Ruben van 't Slot, Gabriel J.E. Rinkel, Ynte M. Ruigrok

Publikováno v: Stroke, 39(4), 1096-1102. LIPPINCOTT WILLIAMS & WILKINS
Stroke; a journal of cerebral circulation, 39(4), 1096-1102. Lippincott Williams and Wilkins

Background and Purpose— Approximately 2% of the general population harbor intracranial aneurysms. The prognosis after rupture of an intracranial aneurysm is poor; 50% of the patients die as a result of the rupture. Familial occurrence of intracrani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e371e87b7fcdb9258c7a04cc752c6b0
https://pubmed.ncbi.nlm.nih.gov/18309175

PS4 - 19. Expression of lipid genes, but not adipokine genes, in visceral adipose tissue is related to liver damage in obese individuals

Autor: Marten H. Hofker, Marcel Wolfs, Bart van de Sluis, Jingyuan Fu, Timon W. van Haeften, Wim A. Buurman, Ann Driessen, Ciska Wijmenga, Lude Franke, Sander S. Rensen, Jan Greve, Ludger Scheja

Publikováno v: Nederlands Tijdschrift voor Diabetologie. 9:103-103

Obesity increases the risk to develop liver steatosis, inflammation, and consequently severe liver damage. This risk is associated with an increased flow of lipids and signaling molecules (adipokines), secreted by adipose tissue, through the liver. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f122d62014e7a560f815b6637fa38425
https://doi.org/10.1007/s12467-011-0044-1