RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease

Autor: Leticia Pérez-Sisqués, Anna Sancho-Balsells, Júlia Solana-Balaguer, Genís Campoy-Campos, Marcel Vives-Isern, Ferran Soler-Palazón, Marta Anglada-Huguet, Miguel-Ángel López-Toledano, Eva-Maria Mandelkow, Jordi Alberch, Albert Giralt, Cristina Malagelada

Publikováno v: Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)

Abstract RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death. Its downregulation in Parkinson’s and Huntington’s disease models ameliorates the pathological phenotypes. In the contex

Externí odkaz: https://doaj.org/article/dd2fb29473404df5adcecc84c09efbe1

RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease

Autor: Genís Campoy-Campos, Marta Anglada-Huguet, Miguel-Ángel López-Toledano, Eva-Maria Mandelkow, Anna Sancho-Balsells, Júlia Solana-Balaguer, Ferran Soler-Palazón, Leticia Pérez-Sisqués, Jordi Alberch, Cristina Malagelada, Albert Giralt, Marcel Vives-Isern

Publikováno v: Cell Death & Disease
Cell death & disease 12(6), 616 (2021). doi:10.1038/s41419-021-03899-y
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Cell Death and Disease

RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death. Its downregulation in Parkinson’s and Huntington’s disease models ameliorates the pathological phenotypes. In the context of Alzh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c1f33bee35f24c79ef49b0cf714a3a
https://doi.org/10.1038/s41419-021-03899-y