Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Marcel Reinders"'
Autor:
Jeppe Severens, Onur Karakaslar, Elena Sánchez- López, Redmar Van den Berg, Hendrik Veelken, Marcel Reinders, Marieke Griffioen, Erik Van den Akker
Publikováno v:
HemaSphere, Vol 7, p e495610f (2023)
Externí odkaz:
https://doaj.org/article/9de6dc6c8e534a82b18f157cd6b038c6
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284493 (2023)
BackgroundNon-Invasive Prenatal Testing is often performed by utilizing read coverage-based profiles obtained from shallow whole genome sequencing to detect fetal copy number variations. Such screening typically operates on a discretized binned repre
Externí odkaz:
https://doaj.org/article/2d1bb8c724af46d38c366ab135de6893
Autor:
Skander Tahar Mulder, Amir-Houshang Omidvari, Anja J Rueten-Budde, Pei-Hua Huang, Ki-Hun Kim, Babette Bais, Melek Rousian, Rihan Hai, Can Akgun, Jeanine Roeters van Lennep, Sten Willemsen, Peter R Rijnbeek, David MJ Tax, Marcel Reinders, Eric Boersma, Dimitris Rizopoulos, Valentijn Visch, Régine Steegers-Theunissen
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 9, p e35675 (2022)
A digital twin (DT), originally defined as a virtual representation of a physical asset, system, or process, is a new concept in health care. A DT in health care is not a single technology but a domain-adapted multimodal modeling approach incorporati
Externí odkaz:
https://doaj.org/article/96a1f3e8792646d0b25b6f431e14ebb1
Autor:
Maxine D. Rouvroye, Pauline Slottje, Tom van Gils, Chris J. Mulder, Jean W. Muris, Dick Walstock, Marcel Reinders, Gerd Bouma
Publikováno v:
European Journal of General Practice, Vol 27, Iss 1, Pp 313-319 (2021)
Background Coeliac disease (CD) is a highly prevalent (∼1%) disease that allegedly remains undiagnosed in over 80% of the cases because of atypical symptoms or silent disease. Currently, it is unknown how GPs deal with (suspected) CD. Objectives Th
Externí odkaz:
https://doaj.org/article/2c9623cfed104df48de490f91fc6c84b
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract The practical use of graph-based reference genomes depends on the ability to align reads to them. Performing substring queries to paths through these graphs lies at the core of this task. The combination of increasing pattern length and enco
Externí odkaz:
https://doaj.org/article/0929ce795723466791944e5220ddf9bd
Autor:
Christian Groß, Martijn Derks, Hendrik-Jan Megens, Mirte Bosse, Martien A. M. Groenen, Marcel Reinders, Dick de Ridder
Publikováno v:
Genetics Selection Evolution, Vol 52, Iss 1, Pp 1-15 (2020)
Abstract Background In animal breeding, identification of causative genetic variants is of major importance and high economical value. Usually, the number of candidate variants exceeds the number of variants that can be validated. One way of prioriti
Externí odkaz:
https://doaj.org/article/69a7c63b694b4f8ba04c4e9109410dc8
Autor:
David Lähnemann, Johannes Köster, Ewa Szczurek, Davis J. McCarthy, Stephanie C. Hicks, Mark D. Robinson, Catalina A. Vallejos, Kieran R. Campbell, Niko Beerenwinkel, Ahmed Mahfouz, Luca Pinello, Pavel Skums, Alexandros Stamatakis, Camille Stephan-Otto Attolini, Samuel Aparicio, Jasmijn Baaijens, Marleen Balvert, Buys de Barbanson, Antonio Cappuccio, Giacomo Corleone, Bas E. Dutilh, Maria Florescu, Victor Guryev, Rens Holmer, Katharina Jahn, Thamar Jessurun Lobo, Emma M. Keizer, Indu Khatri, Szymon M. Kielbasa, Jan O. Korbel, Alexey M. Kozlov, Tzu-Hao Kuo, Boudewijn P.F. Lelieveldt, Ion I. Mandoiu, John C. Marioni, Tobias Marschall, Felix Mölder, Amir Niknejad, Alicja Rączkowska, Marcel Reinders, Jeroen de Ridder, Antoine-Emmanuel Saliba, Antonios Somarakis, Oliver Stegle, Fabian J. Theis, Huan Yang, Alex Zelikovsky, Alice C. McHardy, Benjamin J. Raphael, Sohrab P. Shah, Alexander Schönhuth
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Abstract The recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands—or even millions—of cells analyzed in a single experiment amount to a
Externí odkaz:
https://doaj.org/article/9368dc7f34b5489abc7fc8743d7a022d
Publikováno v:
JMIR Medical Informatics, Vol 10, Iss 1, p e29434 (2022)
BackgroundWearable technology has the potential to improve cardiovascular health monitoring by using machine learning. Such technology enables remote health monitoring and allows for the diagnosis and prevention of cardiovascular diseases. In additio
Externí odkaz:
https://doaj.org/article/0d4c5131802a4fcc881800c8b379bebb
Publikováno v:
Evolutionary Bioinformatics, Vol 17 (2021)
Computationally annotating proteins with a molecular function is a difficult problem that is made even harder due to the limited amount of available labeled protein training data. Unsupervised protein embeddings partly circumvent this limitation by l
Externí odkaz:
https://doaj.org/article/6517605b2ea149948d0f7ac12058a55c
Autor:
Christian Groß, Chiara Bortoluzzi, Dick de Ridder, Hendrik-Jan Megens, Martien A M Groenen, Marcel Reinders, Mirte Bosse
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009027 (2020)
The availability of genomes for many species has advanced our understanding of the non-protein-coding fraction of the genome. Comparative genomics has proven itself to be an invaluable approach for the systematic, genome-wide identification of conser
Externí odkaz:
https://doaj.org/article/a98a6a16c5d4453bbcf6d2541d225559