Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marcel Morgenstern"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The inner membrane assembly complex (INAC) interacts with components of the F1F0-ATP synthase but its function remains unclear. Here the authors show that INAC associates with two distinct complexes during F1F0-ATP synthase formation, which points to
Externí odkaz:
https://doaj.org/article/fab469cfe0cf474e93bab6274a6e4024
Autor:
Marcel Morgenstern, Sebastian B. Stiller, Philipp Lübbert, Christian D. Peikert, Stefan Dannenmaier, Friedel Drepper, Uri Weill, Philipp Höß, Reinhild Feuerstein, Michael Gebert, Maria Bohnert, Martin van der Laan, Maya Schuldiner, Conny Schütze, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2836-2852 (2017)
Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling, and their dysfunction has been linked to numerous diseases. The available studies cover only part of the mitochondrial proteome, and a separation of core mit
Externí odkaz:
https://doaj.org/article/afe2beb6dfb24cbab29ea223b1e61717
Autor:
Christian D. Peikert, Jan Mani, Marcel Morgenstern, Sandro Käser, Bettina Knapp, Christoph Wenger, Anke Harsman, Silke Oeljeklaus, André Schneider, Bettina Warscheid
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Knowing the specific protein content of individual organelles is necessary for an integrated understanding of cellular physiology. Here the authors describe a mass spectrometry-based approach to identify the substrates of distinct protein import path
Externí odkaz:
https://doaj.org/article/bf7073abf7dd409ea6d6cecc74034615
Autor:
Josie A. Christopher, Charlotte Stadler, Claire E. Martin, Marcel Morgenstern, Yanbo Pan, Cora N. Betsinger, David G. Rattray, Diana Mahdessian, Anne-Claude Gingras, Bettina Warscheid, Janne Lehtiö, Ileana M. Cristea, Leonard J. Foster, Andrew Emili, Kathryn S. Lilley
Publikováno v:
Nature Reviews Methods Primers
Nat Rev Methods Primers
Nat Rev Methods Primers
The eukaryotic cell is compartmentalized into subcellular niches, including membrane-bound and membrane-less organelles. Proteins localize to these niches to fulfil their function, enabling discreet biological processes to occur in synchrony. Dynamic
Autor:
Ida Suppanz, Marcel Morgenstern, Laura Melchionda, Conny Steiert, Sven Dennerlein, Nils Wiedemann, Bettina Warscheid, Nataliia Naumenko, Oliver Alka, Cinzia Klemm, Christopher Eickhorst, Sebastian B. Stiller, Silke Oeljeklaus, Christian D. Peikert, Claudine Kraft, Alexander Schendzielorz, Wignand W. D. Mühlhäuser, Caroline Lindau, Philipp Lübbert, Nikolaus Pfanner, Stefan Dannenmaier, Bettina Knapp, Jakob D. Busch, Riccardo Galbusera, Mariya Licheva, Friedel Drepper, Vera Kozjak-Pavlovic, Michael T. Ryan, Ralf M. Zerbes
Publikováno v:
Cell Metabolism
Summary Mitochondria are key organelles for cellular energetics, metabolism, signaling, and quality control and have been linked to various diseases. Different views exist on the composition of the human mitochondrial proteome. We classified >8,000 p
Autor:
Sebastian B. Stiller, Nils Wiedemann, Marcel Morgenstern, Silke Oeljeklaus, Bettina Warscheid, Philipp Lübbert, Stefan Dannenmaier
Publikováno v:
Analytical Chemistry
Knowledge about the functions of individual proteins on a system-wide level is crucial to fully understand molecular mechanisms underlying cellular processes. A considerable part of the proteome across all organisms is still poorly characterized. Mas
Autor:
Christian D. Peikert, André Schneider, Anke Judith Harsman, Christoph Wenger, Bettina Warscheid, Marcel Morgenstern, Bettina Knapp, Silke Oeljeklaus, Jan Mani, Sandro Käser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Peikert, Christian D.; Mani, Jan; Morgenstern, Marcel; Käser, Sandro; Knapp, Bettina; Wenger, Christoph; Harsman, Anke Judith; Oeljeklaus, Silke; Schneider, André; Warscheid, Bettina (2017). Charting organellar importomes by quantitative mass spectrometry. Nature communications, 8(1), p. 15272. Nature Publishing Group 10.1038/ncomms15272
Nature Communications
Peikert, Christian D.; Mani, Jan; Morgenstern, Marcel; Käser, Sandro; Knapp, Bettina; Wenger, Christoph; Harsman, Anke Judith; Oeljeklaus, Silke; Schneider, André; Warscheid, Bettina (2017). Charting organellar importomes by quantitative mass spectrometry. Nature communications, 8(1), p. 15272. Nature Publishing Group 10.1038/ncomms15272
Nature Communications
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analysing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowled