Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marcel Madej"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5066-5084 (2024)
Alzheimer’s disease (AD) is the world’s most common neurodegenerative disease, expected to affect up to one-third of the elderly population in the near future. Among the major challenges in combating AD are the inability to reverse the damage cau
Externí odkaz:
https://doaj.org/article/ce97b526962348498a150757c6af1b04
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5436-5453 (2024)
Neurodegenerative diseases are a diverse group of diseases characterized by a progressive loss of neurological function due to damage to nerve cells in the central nervous system. In recent years, there has been a worldwide increase in the expanding
Externí odkaz:
https://doaj.org/article/934639a8c4104f598f27e613b205be84
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 121-139 (2023)
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and is responsible for approximately one million deaths each year. The current standard of care is surgical resection of the lesion and chemotherapy with 5-fluorouracil (5-FU). How
Externí odkaz:
https://doaj.org/article/be72817f4e7d4914ab7c80ab267701d0
Autor:
Marcel Madej, Celina Kruszniewska-Rajs, Magdalena Kimsa-Dudek, Agnieszka Synowiec-Wojtarowicz, Elwira Chrobak, Ewa Bębenek, Stanisław Boryczka, Stanisław Głuszek, Jolanta Adamska, Sebastian Kubica, Jarosław Matykiewicz, Joanna Magdalena Gola
Publikováno v:
Cells, Vol 13, Iss 16, p 1368 (2024)
Oxidative stress is considered one of the main reasons for the development of colorectal cancer (CRC). Depending on the stage of the disease, variable activity of the main antioxidant enzymes, i.e., superoxide dismutase (SOD), catalase (CAT) and glut
Externí odkaz:
https://doaj.org/article/a61ddc12b59148a1ac8ad9148a6322f9
Autor:
Barbara Strzalka-Mrozik, Marcel Madej, Natalia Kurowska, Celina Kruszniewska-Rajs, Magdalena Kimsa-Dudek, Jolanta Adamska, Joanna Magdalena Gola
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1500-1518 (2023)
Retinal pigment epithelium (RPE) is a specialized structure essential for proper vision, which is constantly exposed to oxidative damage. With aging, this damage accumulates within the RPE cells, causing various diseases, including age-related macula
Externí odkaz:
https://doaj.org/article/87055affeaa34ebe9a4716515ba9f528
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2768 (2023)
Gastrointestinal (GI) cancers are an increasingly common type of malignancy, caused by the unhealthy lifestyles of people worldwide. Limited methods of treatment have prompted the search for new compounds with antitumor activity, in which betulin (BE
Externí odkaz:
https://doaj.org/article/3cee230b4f944dacb2b84a3a5b7d4bdc
Autor:
Robert Kubina, Kamil Krzykawski, Arkadiusz Sokal, Marcel Madej, Arkadiusz Dziedzic, Monika Kadela-Tomanek
Publikováno v:
Cells, Vol 12, Iss 18, p 2288 (2023)
Head and neck cancer (HNC) therapy is limited; therefore, new solutions are increasingly being sought among flavonoids, which exhibit numerous biological properties, including potential anticancer activity. However, because they are mostly insoluble
Externí odkaz:
https://doaj.org/article/0506fbe7bfd1450781a1e7ce979304ab
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1931 (2023)
Central nervous system (CNS) diseases are currently a major challenge in medicine. One reason is the presence of the blood–brain barrier, which is a significant limitation for currently used medicinal substances that are characterized by a high mol
Externí odkaz:
https://doaj.org/article/f7408d65c52e4bf8a863086590e32252
Publikováno v:
Molecules, Vol 28, Iss 13, p 5081 (2023)
Chemoprevention is one of the ways to fight colorectal cancer, which is a huge challenge in oncology. Numerous pieces of evidence indicate that chronic inflammation in the course of Crohn’s disease or ulcerative colitis (UC) is a significant cancer
Externí odkaz:
https://doaj.org/article/f3c254c204df46d590ea6d6d62038ce5
Publikováno v:
Applied Sciences, Vol 12, Iss 19, p 9479 (2022)
The increase in cancer cases is undoubtedly affecting the development of new therapeutic approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size, the possibility of incorporating into them medicinal substances an
Externí odkaz:
https://doaj.org/article/051810f7288a4840899454fef7c86354