Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marcel Lindemann"'
Autor:
Richard Pracitto, Kyle C. Wilcox, Marcel Lindemann, Jie Tong, Chao Zheng, Songye Li, Sjoerd J. Finnema, Yiyun Huang, Zhengxin Cai
Publikováno v:
ACS Omega, Vol 6, Iss 42, Pp 27676-27683 (2021)
Externí odkaz:
https://doaj.org/article/17f3b403611a4645aecb1b92f553a4b4
Autor:
Marcel Lindemann, Sladjana Dukic-Stefanovic, Sonja Hinz, Winnie Deuther-Conrad, Rodrigo Teodoro, Cathleen Juhl, Jörg Steinbach, Peter Brust, Christa E. Müller, Barbara Wenzel
Publikováno v:
Pharmaceuticals, Vol 14, Iss 5, p 485 (2021)
The G protein-coupled adenosine A2B receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A2B receptor is currently
Externí odkaz:
https://doaj.org/article/8fffc158d73a484d866392b9189d0100
Autor:
Marcel Lindemann, Rareş-Petru Moldovan, Sonja Hinz, Winnie Deuther-Conrad, Daniel Gündel, Sladjana Dukic-Stefanovic, Magali Toussaint, Rodrigo Teodoro, Cathleen Juhl, Jörg Steinbach, Peter Brust, Christa E. Müller, Barbara Wenzel
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3197 (2020)
The adenosine A2B receptor has been proposed as a novel therapeutic target in cancer, as its expression is drastically elevated in several tumors and cancer cells. Noninvasive molecular imaging via positron emission tomography (PET) would allow the i
Externí odkaz:
https://doaj.org/article/34a0e0aaba6c43b7b4fc0534b020bc15
Autor:
Ming-Qiang Zheng, Sjoerd J. Finnema, Richard Pracitto, Zhengxin Cai, Jie Tong, Nabeel Nabulsi, Chao Zheng, Zachary Felchner, Krista Fowles, Yiyun Huang, Marcel Lindemann, Li Zhang, Richard E. Carson, Daniel Holden, Kyle C. Wilcox
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1482-1496
Purpose To quantify the synaptic vesicle glycoprotein 2A (SV2A) changes in the whole central nervous system (CNS) under pathophysiological conditions, a high affinity SV2A PET radiotracer with improved in vivo stability is desirable to minimize the p
Autor:
Sjoerd J. Finnema, Chao Zheng, Marcel Lindemann, Songye Li, Kyle C. Wilcox, Zhengxin Cai, Yiyun Huang, Jie Tong, Richard Pracitto
Publikováno v:
ACS Omega, Vol 6, Iss 42, Pp 27676-27683 (2021)
ACS Omega
ACS Omega
A series of synaptic vesicle protein 2A (SV2A) ligands were synthesized to explore the structure-activity relationship and to help further investigate a hydrogen bonding pharmacophore hypothesis. Racemic SynVesT-1 was used as a lead compound to explo
Autor:
Marcel, Lindemann, Ana, Oteiza, Montserrat, Martin-Armas, Yngve, Guttormsen, Angel, Moldes-Anaya, Rodrigo, Berzaghi, Trond Velde, Bogsrud, Tore, Bach-Gansmo, Rune, Sundset, Mathias, Kranz
Publikováno v:
European journal of nuclear medicine and molecular imaging.
Glioblastoma multiforme (GBM) is the most common glioma and standard therapies can only slightly prolong the survival. Neo-vascularization is a potential target to image tumor microenvironment, as it defines its brain invasion. We investigate [[[[
Autor:
Marcel Lindemann, Ana Oteiza, Montserrat Martin-Armas, Yngve Guttormsen, Angel Moldes-Anaya, Rodrigo Berzaghi, Trond Velde Bogsrud, Tore Bach-Gansmo, Rune Sundset, Mathias Kranz
Publikováno v:
Lindemann, M, Oteiza, A, Martin-Armas, M, Guttormsen, Y, Moldes-Anaya, A, Berzaghi, R, Bogsrud, T V, Bach-Gansmo, T, Sundset, R & Kranz, M 2023, ' Glioblastoma PET/MRI : kinetic investigation of [ 18 F]rhPSMA-7.3, [ 18 F]FET and [ 18 F]fluciclovine in an orthotopic mouse model of cancer ', European journal of nuclear medicine and molecular imaging, vol. 50, no. 4, pp. 1183-1194 . https://doi.org/10.1007/s00259-022-06040-z
Purpose Glioblastoma multiforme (GBM) is the most common glioma and standard therapies can only slightly prolong the survival. Neo-vascularization is a potential target to image tumor microenvironment, as it defines its brain invasion. We investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695569f55370c5f051c0f08d3aa9e7d1
https://hdl.handle.net/10037/28555
https://hdl.handle.net/10037/28555
Autor:
Ming-Qiang Zheng, Richard E. Carson, Marcel Lindemann, Zhengxin Cai, Chi Liu, Hui Liu, Michael Kapinos, Wenjie Zhang, Shu-fei Lin, Jo-ku Teng, Nabil E. Boutagy, Tim Mulnix, Attila Feher, John C. Stendahl, Edward J. Miller, Jing Wu, Albert J. Sinusas, Yiyun Huang, Jean-Dominique Gallezot
Publikováno v:
Journal of Nuclear Cardiology. 29:216-225
We aimed to develop a dynamic imaging technique for a novel PET superoxide tracer, [18F]DHMT, to allow for absolute quantification of myocardial reactive oxygen species (ROS) production in a large animal model. Six beagle dogs underwent a single base
Autor:
Xiaoai Wu, Nabeel Nabulsi, Daniel Holden, David Labaree, Marcel Lindemann, Takuya Toyonaga, Jim Ropchan, Songye Li, Shu-fei Lin, Yiyun Huang, Evan Baum, Richard Pracitto, Wenjie Zhang, Sjoerd J. Finnema, Zhengxin Cai, Anupama Shirali, Richard E. Carson
Publikováno v:
ACS Chemical Neuroscience. 11:592-603
Synaptic vesicle glycoprotein 2A (SV2A) is a 12-pass transmembrane glycoprotein ubiquitously expressed in presynaptic vesicles. In vivo imaging of SV2A using PET has potential applications in the d...
Autor:
Chao, Zheng, Daniel, Holden, Ming-Qiang, Zheng, Richard, Pracitto, Kyle C, Wilcox, Marcel, Lindemann, Zachary, Felchner, Li, Zhang, Jie, Tong, Krista, Fowles, Sjoerd J, Finnema, Nabeel, Nabulsi, Richard E, Carson, Yiyun, Huang, Zhengxin, Cai
Publikováno v:
European journal of nuclear medicine and molecular imaging. 49(5)
To quantify the synaptic vesicle glycoprotein 2A (SV2A) changes in the whole central nervous system (CNS) under pathophysiological conditions, a high affinity SV2A PET radiotracer with improved in vivo stability is desirable to minimize the potential