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Autor:
Marcel L, Janssen, Wim J, Oyen, Ingrid, Dijkgraaf, Leon F, Massuger, Cathelijne, Frielink, D Scott, Edwards, Milind, Rajopadhye, Henk, Boonstra, Frans H, Corstens, Otto C, Boerman
Publikováno v:
Cancer research. 62(21)
The alpha(v)beta(3) integrin is expressed on proliferating endothelial cells such as those present in growing tumors, as well as on tumor cells of various origin. Tumor-induced angiogenesis can be blocked in vivo by antagonizing the alpha(v)beta(3) i