Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marcel Hijnen"'
Autor:
Victor A. Streltsov, Sukanya Luang, Alys Peisley, Joseph N. Varghese, James R. Ketudat Cairns, Sebastien Fort, Marcel Hijnen, Igor Tvaroška, Ana Ardá, Jesús Jiménez-Barbero, Mercedes Alfonso-Prieto, Carme Rovira, Fernanda Mendoza, Laura Tiessler-Sala, José-Emilio Sánchez-Aparicio, Jaime Rodríguez-Guerra, José M. Lluch, Jean-Didier Maréchal, Laura Masgrau, Maria Hrmova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Enzyme substrates and products often diffuse too rapidly to assess the catalytic implications of these movements. Here, the authors characterise the structural basis of product and substrate diffusion for an exo-hydrolase and discover a substrate-pro
Externí odkaz:
https://doaj.org/article/393023e627f645a0b2087690681cc2f6
Autor:
Hanumant S Tanwar, Keith K Khoo, Megan Garvey, Lynne Waddington, Andrew Leis, Marcel Hijnen, Tony Velkov, Geoff J Dumsday, William J McKinstry, Johnson Mak
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006221 (2017)
The interactions that occur during HIV Pr55Gag oligomerization and genomic RNA packaging are essential elements that facilitate HIV assembly. However, mechanistic details of these interactions are not clearly defined. Here, we overcome previous limit
Externí odkaz:
https://doaj.org/article/958df98a5bb8424bb081bb2b7192b201
Autor:
Jae-Kyung Hyun, Cathy Accurso, Marcel Hijnen, Philipp Schult, Anne Pettikiriarachchi, Alok K Mitra, Fasséli Coulibaly
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002239 (2011)
In contrast to most enveloped viruses, poxviruses produce infectious particles that do not acquire their internal lipid membrane by budding through cellular compartments. Instead, poxvirus immature particles are generated from atypical crescent-shape
Externí odkaz:
https://doaj.org/article/a6ba9e6d863e40cfaeaa097b72fe9f06
Autor:
Cândida F Pereira, Paula C Ellenberg, Kate L Jones, Tara L Fernandez, Redmond P Smyth, David J Hawkes, Marcel Hijnen, Valérie Vivet-Boudou, Roland Marquet, Iain Johnson, Johnson Mak
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17016 (2011)
Due to its small size and versatility, the biarsenical-tetracysteine system is an attractive way to label viral proteins for live cell imaging. This study describes the genetic labeling of the human immunodeficiency virus type 1 (HIV-1) structural pr
Externí odkaz:
https://doaj.org/article/0c04dcbf311646b9973335f082794022
Autor:
Jean-Didier Maréchal, José-Emilio Sánchez-Aparicio, Igor Tvaroška, Jose N. Varghese, Maria Hrmova, José M. Lluch, Sukanya Luang, V.A. Streltsov, A. Peisley, Marcel Hijnen, Jesús Jiménez-Barbero, Ana Ardá, J.R. Ketudat Cairns, Laura Tiessler-Sala, Carme Rovira, Fernanda Mendoza, Mercedes Alfonso-Prieto, Jaime Rodríguez-Guerra, Sébastien Fort, Laura Masgrau
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-09691-z⟩
Universitat Autònoma de Barcelona
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-09691-z⟩
Substrates associate and products dissociate from enzyme catalytic sites rapidly, which hampers investigations of their trajectories. The high-resolution structure of the native Hordeum exo-hydrolase HvExoI isolated from seedlings reveals that non-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30459d11c55b231244ab87c5844aa4a2
https://ddd.uab.cat/record/223394
https://ddd.uab.cat/record/223394
Autor:
Johnson Mak, Marcel Hijnen, Sureshbabu Nagarajan, Hanumant S. Tanwar, William J. McKinstry, Lindsay G. Sparrow, Son T. Pham
Publikováno v:
Protein Expression and Purification. 100:10-18
The HIV-1 Gag precursor protein, Pr55(Gag), is a multi-domain polyprotein that drives HIV-1 assembly. The morphological features of HIV-1 suggested Pr55(Gag) assumes a variety of different conformations during virion assembly and maturation, yet stru
Autor:
Johnson Mak, Marcel Hijnen, Geoff Dumsday, Hanumantsingh Tanwar, Lynne J. Waddington, Andrew Leis, Tony Velkov, William J. McKinstry, Megan Garvey, Keith K. Khoo
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006221 (2017)
PLoS Pathogens, Vol 13, Iss 2, p e1006221 (2017)
The interactions that occur during HIV Pr55Gag oligomerization and genomic RNA packaging are essential elements that facilitate HIV assembly. However, mechanistic details of these interactions are not clearly defined. Here, we overcome previous limit
Autor:
Serena, Bernacchi, Ekram W, Abd El-Wahab, Noé, Dubois, Marcel, Hijnen, Redmond P, Smyth, Johnson, Mak, Roland, Marquet, Jean-Christophe, Paillart
Publikováno v:
RNA biology. 14(1)
The HIV-1 Pr55Gag precursor specifically selects genomic RNA (gRNA) from a large variety of cellular and spliced viral RNAs (svRNAs), however the molecular mechanisms of this selective recognition remains poorly understood. To gain better understandi
Autor:
Jean-Christophe Paillart, Noé Dubois, Serena Bernacchi, Roland Marquet, Marcel Hijnen, Johnson Mak, Ekram W. Abd El-Wahab, Redmond P. Smyth
Publikováno v:
RNA Biology
RNA Biology, Taylor & Francis, 2016, 14 (1), pp.90-103. ⟨10.1080/15476286.2016.1256533⟩
RNA Biology, Taylor & Francis, 2016, 14 (1), pp.90-103. ⟨10.1080/15476286.2016.1256533⟩
The HIV-1 Pr55Gag precursor specifically selects genomic RNA (gRNA) from a large variety of cellular and spliced viral RNAs (svRNAs), however the molecular mechanisms of this selective recognition remains poorly understood. To gain better understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c922b5d91166544b200a7423f35b1bb9
https://hal.archives-ouvertes.fr/hal-02171331
https://hal.archives-ouvertes.fr/hal-02171331
Autor:
John B. Bruning, Mi Ra Chang, Dana S. Kuruvilla, Patrick R. Griffin, Laura M. van Marrewijk, Steven W. Polyak, Youseung Shin, Marcel Hijnen, Theodore M. Kamenecka
Synthetic full agonists of PPARγ have been prescribed for the treatment of diabetes due to their ability to regulate glucose homeostasis and insulin sensitization. While the use of full agonists of PPARγ has been hampered due to severe side effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef1c65a9a684644203b3159b622f1f4
https://hdl.handle.net/11541.2/134089
https://hdl.handle.net/11541.2/134089