Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marcel Hanke"'
Autor:
Julia Ring, Jelena Tadic, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunović, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen, Cornelia Sommer, Mirjana Ninkovic, Sandra Seba, Patrick Rockenfeller, Friederike‐Nora Vögtle, Jörn Dengjel, Chris Meisinger, Adrian Keller, Stephan J Sigrist, Tobias Eisenberg, Frank Madeo
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-26 (2022)
Abstract Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer’s disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic approach using a yeast m
Externí odkaz:
https://doaj.org/article/4c65d2eea54842d29ae6240b593bf7ff
Autor:
Marcel Hanke, Daniel Dornbusch, Christoph Hadlich, Andre Rossberg, Niklas Hansen, Guido Grundmeier, Satoru Tsushima, Adrian Keller, Karim Fahmy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2611-2623 (2022)
While the folding of DNA into rationally designed DNA origami nanostructures has been studied extensively with the aim of increasing structural diversity and introducing functionality, the fundamental physical and chemical properties of these nanostr
Externí odkaz:
https://doaj.org/article/ab6d544f28de4c279fddc9e1dff96764
Autor:
Roozbeh Hajiraissi, Marcel Hanke, Alejandro Gonzalez Orive, Belma Duderija, Ulrike Hofmann, Yixin Zhang, Guido Grundmeier, Adrian Keller
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 2649-2660 (2019)
Externí odkaz:
https://doaj.org/article/7dd22903bffe47b18c0075c9983f62d8
Publikováno v:
Nanomaterials, Vol 10, Iss 11, p 2200 (2020)
The aggregation of human islet amyloid polypeptide (hIAPP) plays a major role in the pathogenesis of type 2 diabetes mellitus (T2DM), and numerous strategies for controlling hIAPP aggregation have been investigated so far. In particular, several orga
Externí odkaz:
https://doaj.org/article/04ae9e0eef884264be3000d5eec198c7
Publikováno v:
ChemBioChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d05b57c7f21247bc1367dfee6dc65a
https://doi.org/10.1002/cbic.202300338
https://doi.org/10.1002/cbic.202300338
Publikováno v:
Nanoscale. 14:11552-11560
The efficient loading of DNA nanostructures with intercalating or groove-binding drugs is an important prerequisite for various applications in drug delivery. However, unambiguous verification and quantification of successful drug loading is often ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c121b074bde0eb297b4c1eabe0e5ae
https://doi.org/10.1039/d2nr02701a
https://doi.org/10.1039/d2nr02701a
Autor:
Dominik Hense, Adrian Keller, Klaus Huber, Anne Büngeler, Fabian Kollmann, Marcel Hanke, Oliver I. Strube, Guido Grundmeier, Alejandro Gonzalez Orive
Publikováno v:
Biomacromolecules
The natural blood protein fibrinogen is a highly potent precursor for the production of various biomaterials due to its supreme biocompatibility and cell interaction. To gain actual materials from fibrinogen, the protein needs to undergo fibrillogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4662b265b607402523adf92c18ed6c9f
https://doi.org/10.1021/acs.biomac.1c00489
https://doi.org/10.1021/acs.biomac.1c00489
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8547
Guanidinium (Gdm) undergoes interactions with both hydrophilic and hydrophobic groups and, thus, is a highly potent denaturant of biomolecular structure. However, our molecular understanding of the interaction of Gdm with proteins and DNA is still ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc1f8fc11d14573da7a92569e8eb706
https://pubmed.ncbi.nlm.nih.gov/35955680
https://pubmed.ncbi.nlm.nih.gov/35955680
Upon subjecting biomolecules to non-equilibrium conditions, many biochemical and biophysical features such as biomolecular diffusion, protein folding, interaction kinetics, as well as enzyme-catalyzed reactions can be characterized in an aqueous solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e654e2857fdc3b8ad836ca597f682fc
https://doi.org/10.1101/2022.04.11.487957
https://doi.org/10.1101/2022.04.11.487957
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2817
International Journal of Molecular Sciences 23(2022)5, 2817
International Journal of Molecular Sciences 23(2022)5, 2817
DNA origami technology enables the folding of DNA strands into complex nanoscale shapes whose properties and interactions with molecular species often deviate significantly from that of genomic DNA. Here, we investigate the salting-out of different D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a930d3f6b8d22c0a311f24966522a9d