Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marcel Grapp"'
Publikováno v:
Journal of analytical toxicology.
α-Pyrrolidinohexiophenone (α-PHP) is a derivative of the class of α-pyrrolidinophenones, a subgroup of synthetic cathinones. These substances are the second most abused drugs of new psychoactive substances. Here, we report the toxicological invest
Autor:
Maurice Wilde, Caroline Despicht, Hartmud Neurath, Sabine Blaschke, D Müller, Merja A. Neukamm, Marcel Grapp
Publikováno v:
Clinical Toxicology. 57:806-812
Introduction: Fentanyl derivatives like cyclopropylfentanyl have recently appeared on the recreational drug market. Cyclopropylfentanyl is probably a highly potent opioid, but human toxicological d...
Autor:
Abass Eidizadeh, Merja A. Neukamm, Sabine Blaschke, Hannes M. Schwelm, Christoph Kaufmann, Marcel Grapp
Publikováno v:
Drug testing and analysisREFERENCES. 12(9)
Among the increasing number of new psychoactive substances, 3',4'-methylenedioxy-α-pyrrolidinohexanophenone (MDPHP) belongs to the group of synthetic cathinones, which are the derivatives of the naturally occurring compound cathinone, the main psych
Publikováno v:
Forensic Science International. 287:63-73
Comprehensive screening procedures for psychoactive agents in body fluids are an essential task in clinical and forensic toxicology. With the continuous emergence and adaption of new psychoactive substances (NPS) keeping a screening method up to date
Publikováno v:
Forensic Science International. 273:1-9
3,4-methylenedioxypyrovalerone (MDPV) is a synthetic cathinone belonging to the class of α-pyrrolidinophenones that become increasingly popular as a designer psychostimulant. Here, we report a comprehensive collection of MDPV exposure with quantitat
Publikováno v:
Forensic Science International. 259:e14-e19
α-Pyrrolidinovalerophenone (α-PVP) is a synthetic cathinone belonging to the group of "second generation" pyrrolidinophenones that becomes more and more popular as a designer psychostimulant. Here we provide toxicological analytical support for a s
Publikováno v:
Drug Testing and Analysis. 8:816-825
Non-targeted screening of body fluids for psychoactive agents is an essential task for forensic toxicology. The challenge is the identification of xenobiotics of interest from background noise and endogenous matrix components. The aim of the present
Autor:
Tarja Linnankivi, Thomas Lücke, Jutta Gärtner, I. A. Just, Robert Steinfeld, Marcel Grapp, Martin Häusler, P. Wolf
Publikováno v:
Brain. 135:2022-2031
Cerebral folate transport deficiency is an inherited brain-specific folate transport defect that is caused by mutations in the folate receptor 1 gene coding for folate receptor alpha (FRα). This genetic defect gives rise to a progressive neurologica
Autor:
Sabine Teichler, Corinna Dickel, Willhart Knepel, Payam Dibaj, Marcel Grapp, Julia Kitz, Ralph Krätzner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1789:403-412
The transcription factor PAX6 plays an important role in transcriptional regulation of the peptide hormone glucagon from pancreatic α-cells. PAX6 contains two DNA binding domains, the paired domain (PD) and the homeodomain (HD). While the interactio
Publikováno v:
European Journal of Organic Chemistry. 2008:2100-2106
Two formacetal-linked dinucleotides TT and TA were synthesized as phosphoramidite building blocks for solid-phase synthesis. Incorporated in a 29-mer DNA, the oligomers P3TT and P3TA were studied with respect to the binding activity towards the Pax6