Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marcel Geyer"'
Publikováno v:
ChemMedChem. 10:911-924
Loperamide (1a), an opioid receptor agonist, is in clinical use as an antidiarrheal agent. Carbon/silicon exchange (sila-substitution) at the 4-position of the piperidine ring of 1a (R3 COH→R3 SiOH) leads to sila-loperamide (1b). Sila-loperamide wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c688d0be65bcb97e7ff655ea114bf94f
https://doi.org/10.1002/cmdc.201500040
https://doi.org/10.1002/cmdc.201500040
Publikováno v:
European Journal of Inorganic Chemistry. 2011:2769-2776
With an odor threshold value of 0.54 ng L–1 air, (3E,5E)-7,7-dimethyl-5-tert-butylocta-3,5-dien-2-one (1a) constitutes the most potent member of a new family of acyclic musk odorants with ionone aspects. Replacement of the quaternary carbon atoms o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df51830935d3f9c0b2155cf6fa88d76
https://doi.org/10.1002/ejic.201100161
https://doi.org/10.1002/ejic.201100161
Autor:
K.-G. Fischer, Thorsten Wiech, Michael Daskalakis, Elke Neumann-Haefelin, Jochen Wilpert, Anna Ziegler, Florian Emmerich, Marcel Geyer, Przemyslaw Pisarski, Oliver Drognitz, Gerd Walz
Publikováno v:
Nephrology Dialysis Transplantation. 25:3778-3786
Background ABO-incompatible living donor kidney transplantation based on specific conditioning has been successfully adopted by transplant centres worldwide. Excellent short-term results have been reported in small cohorts. However, long-term data an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf8aa34496a4863b2e393cbdca857ca
https://doi.org/10.1093/ndt/gfq229
https://doi.org/10.1093/ndt/gfq229
Autor:
Sven Teschner, Gerd Walz, Thomas Benzing, Marcel Geyer, Peter Gerke, B. Krumme, Jochen Wilpert
Publikováno v:
Transplantation Proceedings. 41:2533-2538
Background Optimal treatment of polyomavirus-induced allograft nephropathy (PVAN) with immunosuppressive and antiviral therapy is uncertain at present. Reduced immunosuppression is accompanied by increased risk of rejection, and antiviral agents are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62e8729a16acaf458e68fb82501393d
https://doi.org/10.1016/j.transproceed.2009.06.099
https://doi.org/10.1016/j.transproceed.2009.06.099
Autor:
Martin J. Bek, Stefan Reuter, Rudolf Reichelt, Miriam Stoelting, Marcel Geyer, Hermann Pavenstädt
Publikováno v:
Biochemical and Biophysical Research Communications. 379:81-85
Renal dopamine receptors have been shown to play a critical role in ROS-dependent hypertension. D5 dopamine receptor deficient (D5−/−) mice are hypertensive and have increased systemic oxidative stress which is manifested in the kidney and the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9917c9327b64b2f6ee007f4cfc651a7c
https://doi.org/10.1016/j.bbrc.2008.12.008
https://doi.org/10.1016/j.bbrc.2008.12.008
Autor:
Przemyslaw Pisarski, Marcel Geyer, Peter Gerke, Gerd Walz, Anette Gropp, Johannes Donauer, Sven Teschner, Oliver Drognitz, Heike Goebel, Jochen Wilpert, Christian Schulz-Huotari
Publikováno v:
Nephrology Dialysis Transplantation. 22:3048-3051
Background. Since 2001, approximately 100 ABOincompatible kidney transplantations have been performed in Europe. The standard protocol, employed by most transplant centres, uses rituximab and scheduled pre-emptive antigen-specific immunoadsorption on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873a9831ed5e9aaaf0f9cb423c4303c6
https://doi.org/10.1093/ndt/gfm460
https://doi.org/10.1093/ndt/gfm460
Autor:
Christian Schulz-Huotari, Tobias Schaefer, Sven Teschner, Ursula Wisniewski, Johannes Donauer, Anette Gropp, Gerd Walz, Jochen Wilpert, Przemyslaw Pisarski, Heike Goebel, Marcel Geyer, Peter Gerke
Publikováno v:
Journal of Clinical Apheresis. 22:314-322
Since Tyden's description of ABO-incompatible (ABOi) kidney transplantations based on antigen-specific immunoadsorption (IA) and rituximab (Tyden et al., Am J Transplant 2005;5:145–148), this technique has been successfully adopted by many transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30da0d24f74f455ce68b22a1caaee19a
https://doi.org/10.1002/jca.20153
https://doi.org/10.1002/jca.20153
Autor:
Reinhold Tacke, Marcel Geyer, Eric Wellner, Ola Fjellström, Linda Gustafsson, Johannes A. Baus
Publikováno v:
ChemMedChem. 10(12)
The GPR81 and GPR109A receptors mediate antilipolytic effects and are potential drug targets for the treatment of metabolic disorders such as dyslipidemia and type 2 diabetes. There is still a need to identify potent GPR81 agonists as pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db399b4b1a318fbda0cc2b880fe45329
https://pubmed.ncbi.nlm.nih.gov/26459194
https://pubmed.ncbi.nlm.nih.gov/26459194
Autor:
Anja Neumann, Stefan Zschiedrich, Bernd Jänigen, Maximilian Seidl, Marcel Geyer, Günter Kirste, Tobias B. Huber, Przemyslaw Pisarski, Oliver Drognitz, Silvia Hils, Dilyana Dimova, Albrecht Kramer-Zucker, Ulrich T. Hopt, Florian Emmerich, Gerd Walz
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 31(4)
Background ABO-incompatible kidney transplantation (ABOi KTx) expands the living donor transplantation options. However, long-term outcome data, especially in comparison with ABO-compatible kidney transplantation (ABOc KTx), remain limited. Since the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485c41211bc7945abaf314063611cc08
https://pubmed.ncbi.nlm.nih.gov/26610596
https://pubmed.ncbi.nlm.nih.gov/26610596
Publikováno v:
The Journal of organic chemistry. 80(11)
4-Silacyclohexan-1-ones 1a–1c, 4-silacyclohexan-1-one oximes 2a–2c, 1,4-azasilepan-7-ones 3a–3c, 1,4-azasilepanes 4a–4c, and 2-bromo-4-silacyclohexan-1-ones 5a and 5b were prepared in multistep syntheses, starting from trimethoxypropylsilane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c43a1512030ab45592d6dadc66042e
https://pubmed.ncbi.nlm.nih.gov/25928726
https://pubmed.ncbi.nlm.nih.gov/25928726