Family-Based Benchmarking of Copy Number Variation Detection Software.

Autor: Marcel Elie Nutsua, Annegret Fischer, Almut Nebel, Sylvia Hofmann, Stefan Schreiber, Michael Krawczak, Michael Nothnagel

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0133465 (2015)

The analysis of structural variants, in particular of copy-number variations (CNVs), has proven valuable in unraveling the genetic basis of human diseases. Hence, a large number of algorithms have been developed for the detection of CNVs in SNP array

Externí odkaz: https://doaj.org/article/f8816f9cc90a4aa0a44c8f852e88edd4

Bisnorgammacerane traces predatory pressure and the persistent rise of algal ecosystems after Snowball Earth

Autor: Nilamoni Nath, Klaus Wolkenstein, Marcel Elie, N. B. Kuznetsov, Benjamin J. Nettersheim, Paul K. Strother, Jaap S. Sinninghe Damsté, Lars Wörmer, Marcus Elvert, Johan W.H. Weijers, Christian Griesinger, Jens Hefter, Lennart van Maldegem, Pierre Sansjofre, Gerd Gleixner, Yosuke Hoshino, Christian Hallmann, Erik Tegelaar, Stefan Schouten

Publikováno v: Nature Communications, 10(1). Nature Publishing Group
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Nature Publishing Group, 2019, 10, ⟨10.1038/s41467-019-08306-x⟩
EPIC3Nature Communications, 10(1), ISSN: 2041-1723
Nature Communications (2041-1723) (Nature Publishing Group), 2019-01, Vol. 10, P. 476 (11p.)

Eukaryotic algae rose to ecological relevance after the Neoproterozoic Snowball Earth glaciations, but the causes for this consequential evolutionary transition remain enigmatic. Cap carbonates were globally deposited directly after these glaciations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daaa7935bf25600aaeb6332fa11bfab
https://www.vliz.be/imisdocs/publications/54/323054.pdf

Family-Based Benchmarking of Copy Number Variation Detection Software.

Autor: Nutsua, Marcel Elie¹, Fischer, Annegret¹, Nebel, Almut¹, Hofmann, Sylvia¹, Schreiber, Stefan¹, Krawczak, Michael², Nothnagel, Michael^2,3 michael.nothnagel@uni-koeln.de

Publikováno v: PLoS ONE. 7/21/2015, Vol. 10 Issue 7, p1-17. 17p.

Biomarker transformations as constraints for the depositional environment and for maximum temperatures during burial of Opalinus Clay and Posidonia Shale in northern Switzerland

Autor: Martin Mazurek, Marcel Elie

Publikováno v: Applied Geochemistry. 23:3337-3354

Samples from two argillaceous formations (Opalinus Clay and Posidonia Shale) of near-identical maturity from northern Switzerland were subjected to a geochemical characterisation of organic matter and to confined-system pyrolysis experiments. Through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0beb5cd3e1a353a1d544bd5f1c45e0a3
https://doi.org/10.1016/j.apgeochem.2008.05.022

Hydrothermal Stability of Adenine Under Controlled Fugacities of N2, CO2 and H2

Autor: Chinh Nguyen-Trung, Marcel Elie, Laurent Richard, Erwan Perfetti, Michael Franiatte, Douglas E. LaRowe

Publikováno v: Origins of Life and Evolution of Biospheres
Origins of Life and Evolution of Biospheres, Springer Verlag, 2008, 38, pp.139-148. ⟨10.1007/s11084-008-9126-5⟩

An experimental study has been carried out on the stability of adenine (one of the five nucleic acid bases) under hydrothermal conditions. The experiments were performed in sealed autoclaves at 300 degrees C under fugacities of CO(2), N(2) and H(2) s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4036cc9be05762e650e2c13298fc456a
https://doi.org/10.1007/s11084-008-9126-5