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Autor:
Robert C. Bast, Susan R. Pilat, Kevin P. Webster, Michael A. Mallamaci, Dwana Sanders, Eileen Babcock, Jill Van Wart Hood, Razelle Kurzrock, Stanley D. Tucker, Steven Strand, Marcel Bartolazzi
Publikováno v:
Journal of Clinical Oncology. 27:4433-4440
Drug development in cancer research is lengthy and expensive. One of the rate-limiting steps is the initiation of first-in-human (phase I) trials. Three to 6 months can elapse between investigational new drug (IND) approval by the US Food and Drug Ad