Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marc-Philipp Pfeil"'
Publikováno v:
PeerJ, Vol 3, p e798 (2015)
Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protea
Externí odkaz:
https://doaj.org/article/eb96095fedde4945a6be13b488edf1f8
Autor:
Nathanael S. Gray, Marc-Philipp Pfeil, Jinhua Wang, Wenlong Lian, Chih-Yun Hsia, Nicholas Kwiatkowski, Jaebong Jang, Priscilla L. Yang, Jared D. Pitts, Zhengnian Li
Publikováno v:
Antiviral Research. 164:147-153
The recent emergence of Zika virus, a mosquito-borne flavivirus, in the Americas has shed light on the severe neurological diseases associated with infection, notably congenital microcephaly in newborns and Guillain-Barré syndrome in adults. Despite
Autor:
Jason Crain, Valeria Losasso, Martyn Winn, Hasan Alkassem, Peter J. Judge, Maxim G. Ryadnov, Nilofar Faruqui, Bart W. Hoogenboom, Marc-Philipp Pfeil, Anthony Watts, Katharine Hammond, Baptiste Lamarre, Glenn J. Martyna, Jascindra Ravi, Alice L. B. Pyne
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
The spread of antimicrobial resistance stimulates discovery strategies that place emphasis on mechanisms circumventing the drawbacks of traditional antibiotics and on agents that hit multiple targets. Host defense peptides (HDPs) are promising candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd108fad3886dd742387d655a71d41a
https://ora.ox.ac.uk/objects/uuid:331ba5c6-9467-4a31-94b3-e8fd1576a8e9
https://ora.ox.ac.uk/objects/uuid:331ba5c6-9467-4a31-94b3-e8fd1576a8e9
Autor:
Brett D. Lindenbach, Marc-Philipp Pfeil, Paula Montero Llopis, Priscilla L. Yang, Chih-Yun Hsia, Valerie A. Villareal, Dominique J. Burri, Mary A. Rodgers, Lorillee Tallorin
Publikováno v:
The Journal of Biological Chemistry
Many RNA viruses create specialized membranes for genome replication by manipulating host lipid metabolism and trafficking, but in most cases, we do not know the molecular mechanisms responsible or how specific lipids may impact the associated membra
Autor:
Angelo Bella, Isabel Bennett, Eleonora Cerasoli, Jason Crain, André Henrion, Anthony Watts, Alice L. B. Pyne, Anita Roethke, Chris R. M. Grovenor, Nilofar Faruqui, Santanu Ray, Jascindra Ravi, Haibo Jiang, Daniel Yin, Marc Philipp Pfeil, Peter J. Judge, Juan C. Muñoz-García, Baptiste Lamarre, Bart W. Hoogenboom, Patrizia Iavicoli, Luigi Calzolai, Maxim G. Ryadnov, Benjamin Little, Bernd Reisinger, Glenn J. Martyna
Publikováno v:
Chemical Science
A novel mechanism of monolayer poration leading to the rapid exfoliation and lysis of microbial membranes is reported.
The spread of bacterial resistance to traditional antibiotics continues to stimulate the search for alternative antimicrobial
The spread of bacterial resistance to traditional antibiotics continues to stimulate the search for alternative antimicrobial
Autor:
Marc-Philipp Pfeil, Anthony Watts
The development of microbial resistance to common small molecule antibiotics is continuing to be a thread to modern medicine and drives the search for novel antibiotics for the clinic. Antimicrobial peptides (AMPs), part of the innate immune system,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ac3aed0eb12fb271b929ef9da8cea4
https://doi.org/10.1039/9781788010627-00146
https://doi.org/10.1039/9781788010627-00146
Autor:
Anthony Watts, Krisztina Varga, Lubica Asilmovska, Marc Philipp Pfeil, Peter J. Judge, Victoria A. Higman, Garrick F. Taylor, Hugh R. W. Dannatt
Publikováno v:
Journal of Biomolecular NMR. 62:17-23
We demonstrate that 13C-detected spectra recorded using fast (60 kHz) magic angle spinning on sub-milligram (
Autor:
Bart W. Hoogenboom, Alice L. B. Pyne, Hasan Alkassem, Katharine Hammond, Baptiste Lamarre, Jascindra Ravi, Marc-Philipp Pfeil, Peter J. Judge, Glenn J. Martyna, Valeria Losasso, Nilofar Faruqui, Martyn Winn, Anthony Watts, Jason Crain, Maxim G. Ryadnov
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports
Scientific Reports
The spread of antimicrobial resistance stimulates discovery strategies that place emphasis on mechanisms circumventing the drawbacks of traditional antibiotics and on agents that hit multiple targets. Host defense peptides (HDPs) are promising candid
Autor:
Hugh R W, Dannatt, Garrick F, Taylor, Krisztina, Varga, Victoria A, Higman, Marc-Philipp, Pfeil, Lubica, Asilmovska, Peter J, Judge, Anthony, Watts
Publikováno v:
Journal of biomolecular NMR. 62(1)
We demonstrate that (13)C-detected spectra recorded using fast (60 kHz) magic angle spinning on sub-milligram (10 μmol) quantities of a protonated 7 trans-membrane helix protein (bacteriorhodopsin) in its native lipid environment are comparable in s
Publikováno v:
PeerJ
PeerJ, Vol 3, p e798 (2015)
PeerJ, Vol 3, p e798 (2015)
Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protea