Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marc-Olivier Boily"'
Autor:
John Knight, Alexandre Caron, Jayakumar Surendradoss, Oliver Chong, David A. Powell, Joyce Wu, Valerie Dumais, Aaron H. Graff, Samuel Gaudreault, Ding Jinyue, Renata Oballa, Andrew T. King, Tim Tang, Rajesh Gumpena, Jennifer H Cox, W. Todd Lowther, Marc-Olivier Boily
Publikováno v:
ACS Med Chem Lett
[Image: see text] Both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA) influence the endogenous synthesis of oxalate and are clinically validated targets for treatment of primary hyperoxaluria (PH). We investigated whether dual inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2657ef881efc3975d21c823aaea40e
https://europepmc.org/articles/PMC8274068/
https://europepmc.org/articles/PMC8274068/
Autor:
Vincent Pichette, François A. Leblond, Line Ste-Marie, Marie-Claude Duquet, Chantal Boudreau, Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, Jean-François Lévesque
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 43(12)
1-Aminobenzotriazole (ABT) is regularly used in vivo as a nonspecific and irreversible cytochrome P450 inhibitor to elucidate the role of metabolism on the pharmacokinetic profile of xenobiotics. However, few reports have considered the recent findin
Autor:
Marc-Olivier Boily, Christine Lavoie, Caroline Thériault, Stéphanie Rosciglione, Marilène Paquette
Publikováno v:
Nature communications
The role of Gαs in G protein-coupled receptor (GPCR) signalling at the cell surface is well established. Recent evidence has revealed the presence of Gαs on endosomes and its capacity to elicit GPCR-promoted signalling from this intracellular compa