Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marc-Michael Zaruba"'
Autor:
Lukas Lanser, Gerhard Poelzl, Moritz Messner, Maria Ungericht, Marc‐Michael Zaruba, Jakob Hirsch, Stefan Hechenberger, Stefan Obersteiner, Bernhard Koller, Hanno Ulmer, Guenter Weiss
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Iron deficiency (ID) is a frequent comorbidity in patients with acute (AHF) and chronic heart failure (CHF) associated with morbidity and death. We aimed to better characterize iron homeostasis in patients with heart failure applying diffe
Externí odkaz:
https://doaj.org/article/1564043fad2b4eaa8df9d8ea89805dec
Autor:
Marc-Michael Zaruba, Simon Staggl, Santhosh Kumar Ghadge, Thomas Maurer, Jasmina Gavranovic-Novakovic, Vivek Jeyakumar, Patric Schönherr, Andreas Wimmer, Gerhard Pölzl, Axel Bauer, Moritz Messner
Publikováno v:
Cells, Vol 13, Iss 13, p 1074 (2024)
Activation of the CXCL12/CXCR4/ACKR3 axis is known to aid myocardial repair through ischemia-triggered hypoxia-inducible factor-1α (HIF-1α). To enhance the upregulation of HIF-1α, we administered roxadustat, a novel prolyl hydroxylase inhibitor (P
Externí odkaz:
https://doaj.org/article/fa27c5de99a142788d29eb4235130afd
Autor:
Florian Kocher, Alex Kaser, Felix Escher, Jacob Doerler, Marc‐Michael Zaruba, Moritz Messner, Christine Mussner‐Seeber, Agnes Mayr, Hanno Ulmer, Stephanie Schneiderbauer‐Porod, Christian Ebner, Gerhard Poelzl
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3919-3928 (2020)
Abstract Aims Amyloid cardiomyopathy is an underappreciated cause of morbidity and mortality. Recent evidence suggests that ATTR wild‐type cardiomyopathy (ATTRwt‐CM) is probably much more common than widely appreciated. So far, no data are availa
Externí odkaz:
https://doaj.org/article/de0a3c32300141b08ae3693e1dabcee9
Autor:
Santhosh Kumar Ghadge, Moritz Messner, Herbert Seiringer, Thomas Maurer, Simon Staggl, Tanja Zeller, Christian Müller, Daniela Börnigen, Wolfgang J. Weninger, Stefan H. Geyer, Sieghart Sopper, Anne Krogsdam, Gerhard Pölzl, Axel Bauer, Marc-Michael Zaruba
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5908 (2021)
The chemokine CXCL12 plays a fundamental role in cardiovascular development, cell trafficking, and myocardial repair. Human genome-wide association studies even have identified novel loci downstream of the CXCL12 gene locus associated with coronary a
Externí odkaz:
https://doaj.org/article/d570ff605ead42ca945415642fb45b2c
Autor:
Moritz Messner, Santhosh Kumar Ghadge, Thomas Maurer, Michael Graber, Simon Staggl, Sarah Christine Maier, Gerhard Pölzl, Marc-Michael Zaruba
Publikováno v:
Cells, Vol 9, Iss 9, p 1981 (2020)
Lamins are important filaments forming the inner nuclear membrane. Lamin A is processed by zinc metalloproteinase (ZMPSTE24). Failure to cleave a truncated form of prelamin A—also called progerin—causes Hutchinson–Gilford progeria syndrome a we
Externí odkaz:
https://doaj.org/article/1ab907d1b5cc4071aa35d2239a78c3aa
Autor:
Moritz Messner, Santhosh Kumar Ghadge, Valentina Goetsch, Andreas Wimmer, Jakob Dörler, Gerhard Pölzl, Marc-Michael Zaruba
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196739 (2018)
Mutations in the LMNA gene are a common cause (6-8%) of dilated cardiomyopathy (DCM) leading to heart failure, a growing health care problem worldwide. The premature aging disease Hutchinson-Gilford syndrome (HGPS) is also caused by defined mutations
Externí odkaz:
https://doaj.org/article/954ee0c380b24b74b1917793913c564d
Autor:
Moritz Messner, Santhosh Kumar Ghadge, Thomas Schuetz, Herbert Seiringer, Gerhard Pölzl, Marc-Michael Zaruba
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1976 (2019)
Obesity is a well-described risk factor resulting in premature aging of the cardiovascular system ultimately limiting longevity. Premature cardiac death and aging is the hallmark of Hutchinson–Gilford syndrome (HGPS), a disease caused by defined mu
Externí odkaz:
https://doaj.org/article/3bdc1146e5fe42f4873a0ee8e2b5807d
Autor:
Stefan Aschauer, Nicolas Verheyen, Roland Schwarz, Diana Bonderman, Julia Mascherbauer, Thomas Weber, Renate Kain, Andreas A. Kammerlander, Agnes Mayr, Marc Michael Zaruba, Christian Ebner, Peter P. Rainer, Klemens Ablasser, Christian Nitsche, Matthias Schneider, Roza Badr Eslam, Gerhard Pölzl, Martin Hülsmann, Alexander Kroiss, Susanne Reiter-Malmqvist, Michaela Auer-Grumbach, Jakob Dörler, Matthias Koschutnik, Hermine Agis, Christina Binder, Franz Duca, Marcus Hacker
Publikováno v:
Wiener Klinische Wochenschrift
SummaryThe prevalence and significance of cardiac amyloidosis have been considerably underestimated in the past; however, the number of patients diagnosed with cardiac amyloidosis has increased significantly recently due to growing awareness of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d32d2c886e9ce2eafe2b252fcf4eaf8
http://europepmc.org/articles/PMC7732807
http://europepmc.org/articles/PMC7732807
Autor:
Maria Ungericht, Julia Wanschitz, Alexander S. Kroiss, Christoph Röcken, Thomas Schuetz, Moritz Messner, Marc-Michael Zaruba, Wolfgang N. Loescher, Gerhard Poelzl
Publikováno v:
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
We identified two patients with transthyretin (ATTR) amyloid myopathy (one ATTR variant amyloidosis, ATTRv; one wild-type ATTR amyloidosis, ATTRwt). Myopathy was the initial manifestation in ATTRwt, whereas it followed neuropathy and cardiomyopathy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1954c96a8d241cc85dd4022e8b74bc45
https://pubmed.ncbi.nlm.nih.gov/35581484
https://pubmed.ncbi.nlm.nih.gov/35581484
Publikováno v:
European Heart Journal - Case Reports. 6
Background Eosinophilic myocarditis (EM) is a rare disease with different clinical pictures and disease courses. Little literature is available on the various courses of the disease. Case summary A previously healthy 44-year-old male patient presente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0eae6983da087fab22cdbc651161dce
https://doi.org/10.1093/ehjcr/ytac055
https://doi.org/10.1093/ehjcr/ytac055