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pro vyhledávání: '"Marc-Antoine Campeau"'
Autor:
Marc-Antoine Campeau, Richard L. Leask
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The disruption of the endothelial cell (EC) glycocalyx (GCX) leads to cellular dysfunction promoting inflammation and cardiovascular disease progression. Recent studies have shown that empagliflozin (EMPA; Jardiance), a sodium-glucose cotran
Externí odkaz:
https://doaj.org/article/8106e4cfb2f642f8b2f49c1a0d74a283
Autor:
Marc-Antoine Campeau, Audrey Lortie, Pierrick Tremblay, Marc-Olivier Béliveau, Dominic Dubé, Ève Langelier, Léonie Rouleau
Publikováno v:
BioMedical Engineering OnLine, Vol 16, Iss 1, Pp 1-23 (2017)
Abstract Background Mechanobiological studies allow the characterization of cell response to mechanical stresses. Cells need to be supported by a material with properties similar to the physiological environment. Silicone elastomers have been used to
Externí odkaz:
https://doaj.org/article/0f9e03660a1f429bb9eb99c135163fb2
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202526 (2018)
Wall shear stress gradients (WSSGs) induce an inflammatory phenotype in endothelial cells (ECs) which is hypothesized to be mediated by mechanotransduction through the EC glycocalyx (GCX). We used a three-dimensional in vitro cell culture model with
Externí odkaz:
https://doaj.org/article/8c4e4b99a4ed4d5ab88e3f7c2e5f393c
Publikováno v:
Molecular and Cellular Biochemistry. 459:121-130
The antihyperglycemic agent empagliflozin not only improves glycemic control but has also been associated with clinically meaningful reductions in cardiovascular events. Studies have shown that empagliflozin significantly reduces cardiovascular death
Autor:
Leila Jafari, Eve Langelier, Leonie Rouleau, Marc-Antoine Lauzon, Nathalie Faucheux, Hamid Hassanisaber, Olivier Drevelle, Marc-Antoine Campeau
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 98
Endothelial cell (EC) dysfunction contributes to atherosclerosis, which is associated with arterial stiffening and fibronectin (FN) deposition, by ECs and smooth muscle cells (SMCs). The effect of stiffness on the EC/FN interaction and fibrillar adhe
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202526 (2018)
PLoS ONE
PLoS ONE
Wall shear stress gradients (WSSGs) induce an inflammatory phenotype in endothelial cells (ECs) which is hypothesized to be mediated by mechanotransduction through the EC glycocalyx (GCX). We used a three-dimensional in vitro cell culture model with