Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Marc Y, Donath"'
Autor:
Kaisa Hofwimmer, Joyce de Paula Souza, Narmadha Subramanian, Milica Vujičić, Leila Rachid, Hélène Méreau, Cheng Zhao, Erez Dror, Emelie Barreby, Niklas K. Björkström, Ingrid Wernstedt Asterholm, Marianne Böni-Schnetzler, Daniel T. Meier, Marc Y. Donath, Jurga Laurencikiene
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage and show that adipocyte-specific deletion of IL-1 receptor 1 (IL1R1
Externí odkaz:
https://doaj.org/article/ba5db9b693c1401681bcd5953d8aed76
Autor:
Cassandra Bazile, Magdy M. Abdel Malik, Courtney Ackeifi, Randy L. Anderson, Roy W. Beck, Marc Y. Donath, Sanjoy Dutta, Joseph A. Hedrick, Stephen R. Karpen, Thomas W. H. Kay, Thomas Marder, Marjana Marinac, Jennifer McVean, Robert Meyer, Jeremy Pettus, Teresa Quattrin, Ruud H. J. Verstegen, Joshua A. Vieth, Esther Latres
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. This destruction leads to chronic hyperglycemia, necessitating lifelong insulin therapy to manage blood glucose levels. Typ
Externí odkaz:
https://doaj.org/article/3d839e45f08449c58283852ff8e122f0
Autor:
Milica Wälchli-Popovic, Sophie Monnerat, Angela E. Taylor, Lorna C. Gilligan, Lina Schiffer, Wiebke Arlt, Deborah R. Vogt, Christian De Geyter, Nina Hutter, Marc Y. Donath, Gideon Sartorius, Mirjam Christ-Crain
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChronic low-grade inflammation might contribute to hyperandrogenemia and metabolic complications in polycystic ovary syndrome (PCOS). The proinflammatory cytokine interleukin (IL)-1 stimulates androgen production from ovarian cells, where
Externí odkaz:
https://doaj.org/article/f9d69dc80b9d4028ad3e110759f5c3fa
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Amiodarone-induced thyroid dysfunction (AIT) is a side-effect associated with the use of Amiodarone for the treatment of refractory arrythmias. Resulting hyperthyroidism can precipitate cardiac complications, including cardiac isc
Externí odkaz:
https://doaj.org/article/e85f93ee33c24c6eaa1357cc3ec468d3
Publikováno v:
Diabetes [Diabetes] 2020 Mar; Vol. 69 (3), pp. 494. Date of Electronic Publication: 2020 Jan 13.
Publikováno v:
Diabetes [Diabetes] 2020 Mar; Vol. 69 (3), pp. 493. Date of Electronic Publication: 2020 Jan 13.
Autor:
Dan Yedu Quansah, Antje Horsch, Leah Gilbert, Marc Y. Donath, Jardena J. Puder, the MySweetheart research group
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Women with gestational diabetes mellitus (GDM) have higher insulin resistance and/or reduced secretion, an increased risk of future diabetes and cardiovascular disease, which may be due to a pathological activation of the innate i
Externí odkaz:
https://doaj.org/article/e96a7c02c1c644ffb4c2d4cd7ad4cf10
Autor:
Fabian Wirth, Fabrice D. Heitz, Christine Seeger, Ioana Combaluzier, Karin Breu, Heather C. Denroche, Julien Thevenet, Melania Osto, Paolo Arosio, Julie Kerr-Conte, C. Bruce Verchere, François Pattou, Thomas A. Lutz, Marc Y. Donath, Christoph Hock, Roger M. Nitsch, Jan Grimm
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract In patients with type 2 diabetes, pancreatic beta cells progressively degenerate and gradually lose their ability to produce insulin and regulate blood glucose. Beta cell dysfunction and loss is associated with an accumulation of aggregated
Externí odkaz:
https://doaj.org/article/68eb80d31bdf42208e648a12724a93bf
Publikováno v:
Diabetes [Diabetes] 2018 Nov; Vol. 67 (11), pp. 2479-2480. Date of Electronic Publication: 2018 Sep 13.
Publikováno v:
Diabetes [Diabetes] 2018 Nov; Vol. 67 (11), pp. 2478-2479. Date of Electronic Publication: 2018 Sep 13.