Výsledky vyhledávání - "Marc Wiesehöfer"

Akademický článek

CEACAM expression in an in-vitro prostatitis model

Autor: Irina Kube-Golovin, Mykola Lyndin, Marc Wiesehöfer, Gunther Wennemuth

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundProstatitis is an inflammatory disease of the prostate gland, which affects 2-16% of men worldwide and thought to be a cause for prostate cancer (PCa) development. Carcinoembryogenic antigen-related cell adhesion molecules (CEACAMs) are der

Externí odkaz: https://doaj.org/article/aee781a8544046ada41c40fee6009caa

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Akademický článek

Stromal-epithelial interaction induces GALNT14 in prostate carcinoma cells

Autor: Elena D. Czyrnik, Marc Wiesehöfer, Jaroslaw T. Dankert, Sven Wach, Mathias Wagner, Martin Spahn, Marianna Kruithof de Julio, Gunther Wennemuth

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionCell-cell communication is an important process in healthy tissue but also gains enhanced attention regarding pathological tissue. To date, the tumor microenvironment is gradually brought into focus when studying tumorigenesis. In the pro

Externí odkaz: https://doaj.org/article/2e9955f506ff4e5da1eeed68d036f8f2

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Akademický článek

Epiregulin expression and secretion is increased in castration-resistant prostate cancer

Autor: Marc Wiesehöfer, Benedikt Bernhard Gereon Raczinski, Caroline Wiesehöfer, Jaroslaw Thomas Dankert, Elena Dilara Czyrnik, Martin Spahn, Marianna Kruithof-de Julio, Gunther Wennemuth

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionIn prostate cancer, long-term treatment directed against androgens often leads to the development of metastatic castration-resistant prostate cancer, which is more aggressive and not curatively treatable. Androgen deprivation results in e

Externí odkaz: https://doaj.org/article/379c3b31c06f46b489dac201810d57d3

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Akademický článek

The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells.

Autor: Jaroslaw Thomas Dankert, Marc Wiesehöfer, Elena Dilara Czyrnik, Bernhard B Singer, Nicola von Ostau, Gunther Wennemuth

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200472 (2018)

Prostate carcinoma contain foci of neuroendocrine transdifferentiation, resulting in an increase of androgen-independent neuroendocrine-like (NE) tumor cells, whose number significantly correlates with tumor aggressiveness and thus lower survival rat

Externí odkaz: https://doaj.org/article/d692740102074879b6edd03811d63b0e

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Akademický článek

Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes

Autor: Jaroslaw Szczyrba, Volker Jung, Michaela Beitzinger, Elke Nolte, Sven Wach, Martin Hart, Sandra Sapich, Marc Wiesehöfer, Helge Taubert, Gunther Wennemuth, Norbert Eichner, Thomas Stempfl, Bernd Wullich, Gunter Meister, Friedrich A. Grässer

Publikováno v: Prostate Cancer, Vol 2017 (2017)

Posttranscriptional gene regulation by microRNAs (miRNAs) contributes to the induction and maintenance of prostate carcinoma (PCa). To identify mRNAs enriched or removed from Ago2-containing RISC complexes, these complexes were immunoprecipitated fro

Externí odkaz: https://doaj.org/article/fa3d357e4fd848889507972bcd967529

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CatSper and its CaM‐like Ca 2+ sensor EFCAB9 are necessary for the path chirality of sperm

Autor: Caroline Wiesehöfer, Marc Wiesehöfer, Jaroslaw Thomas Dankert, Jean‐Ju Chung, Nicola Edith von Ostau, Bernhard Bonaventura Singer, Gunther Wennemuth

Publikováno v: FASEB J

Successful fertilization depends on sperm motility adaptation. Ejaculated and activated sperm beat symmetrically in high frequency, move linearly, and swim with clockwise chirality. After capacitation, sperm beat asymmetrically with a lower amplitude

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e959fefcca15bd7e0aa673f84642470
https://doi.org/10.1096/fj.202101656rr

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Impact of RARα and miR-138 on retinoblastoma etoposide resistance

Autor: Maike, Busch, Natalia, Miroschnikov, Jaroslaw Thomas, Dankert, Marc, Wiesehöfer, Klaus, Metz, Harald, Stephan, Nicole, Dünker

Publikováno v: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 43(1)

Retinoblastoma (RB) is the most common childhood eye cancer. Chemotherapeutic drugs such as etoposide used in RB treatment often cause massive side effects and acquired drug resistances. Dysregulated genes and miRNAs have a large impact on cancer pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd059a9e51d2792d84e0dd6f65e528fc
https://pubmed.ncbi.nlm.nih.gov/33935126

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Increased Expression of AKT3 in Neuroendocrine Differentiated Prostate Cancer Cells Alters the Response Towards Anti-Androgen Treatment

Autor: Marc Wiesehöfer, Elena Dilara Czyrnik, Martin Spahn, Saskia Ting, Henning Reis, Jaroslaw Thomas Dankert, Gunther Wennemuth

Publikováno v: Cancers
Volume 13
Issue 3
Cancers, Vol 13, Iss 578, p 578 (2021)

Simple Summary Metastatic castration-resistant prostate cancer is still untreatable, and patients have a very short life expectancy after diagnosis. One factor that makes metastatic castration-resistant prostate cancer so aggressive and difficult to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49019263f7731b021005f9bd3ba9baae
http://europepmc.org/articles/PMC7867287

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Loss of RBMS1 as a regulatory target of miR-106b influences cell growth, gap closing and colony forming in prostate carcinoma

Autor: Sven Wach, Jaroslaw Thomas Dankert, Gunther Wennemuth, Elena Dilâra Czyrnik, Marc Wiesehöfer

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)

Prostate carcinoma (PCa) is the second most commonly diagnosed cancer in males worldwide. Among hereditary genetic mutations and nutrient factors, a link between the deregulation of microRNA (miRNA) expression and the development of prostate carcinom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0ccb997f255fdde755fa07a9bb8022
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85093837294

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ITIH5-Derived Polypeptides Covering the VIT Domain Suppress the Growth of Human Cancer Cells In Vitro

Autor: Michael Rose, Sebastian Huth, Marc Wiesehöfer, Josef Ehling, Corinna Henkel, Julia Steitz, Twan Lammers, Jennifer Kistermann, Oliver Klaas, Maximilian Koch, Sandra Rushrush, Ruth Knüchel, Edgar Dahl

Publikováno v: Cancers 14(3), 488 (2022). doi:10.3390/cancers14030488 special issue: "Special Issue "Advances in Prognosis and Theranostics of Cancer" / Special Issue Editors: Dr. Sudip Mukherjee, Guest Editor; Dr. Manash Paul, Guest Editor"
Cancers; Volume 14; Issue 3; Pages: 488
Cancers, Vol 14, Iss 488, p 488 (2022)

Cancers 14(3), 488 (2022). doi:10.3390/cancers14030488 special issue: "Special Issue "Advances in Prognosis and Theranostics of Cancer" / Special Issue Editors: Dr. Sudip Mukherjee, Guest Editor; Dr. Manash Paul, Guest Editor"
Published by MDPI,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09379f6dd515f9ca9203fd33028f6acb
https://doi.org/10.3390/cancers14030488

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