Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marc Vaillancourt"'
Autor:
Eric M. Yoshida, M.D., M.H.Sc., FR.C.P.C., Leslie B. Lilly, Paul J. Marotta, Andrew L. Mason, Marc Bilodeau, Marc Vaillancourt
Publikováno v:
Annals of Hepatology, Vol 12, Iss 2, Pp 282-293 (2013)
The transition from regular use of cyclosporine to the newer calcineurin-inhibitors, such as tacrolimus, has been suggested as a contributing factor to the “era effect” of worsening outcomes of post-transplant HCV recurrence. This retrospective m
Externí odkaz:
https://doaj.org/article/ab0668c251ca4617b36aa2d3510123d3
Publikováno v:
Circulation. 135
Background: Despite well-recognized standard of care therapies, heart failure (HF) continues to be characterized by high mortality rates. Sacubitril/valsartan, a first-in-class treatment for HF with reduced ejection fraction (HFrEF) provided incremen
Autor:
Mickael Calosso, Yvan Guindon, Gabrielle St-Pierre, Michel Prévost, Guillaume Tambutet, Marc Vaillancourt, Jean-Philippe Gratton, Daniel Charpentier, Mohammed Bencheqroun
Publikováno v:
ACS Medicinal Chemistry Letters. 5:1054-1059
We report on the design and synthesis of molecules having E- and P-selectins blocking activity both in vitro and in vivo. The GlcNAc component of the selectin ligand sialyl Lewis(X) was replaced by an acyclic tether that links two saccharide units. T
Autor:
Marc Vaillancourt, Eric M. Yoshida, Marc Bilodeau, Leslie B. Lilly, Paul Marotta, Andrew Mason
Publikováno v:
Annals of Hepatology, Vol 12, Iss 2, Pp 282-293 (2013)
The transition from regular use of cyclosporine to the newer calcineurin-inhibitors, such as tacrolimus, has been suggested as a contributing factor to the “era effect” of worsening outcomes of post-transplant HCV recurrence. This retrospective m
Autor:
Yvan Guindon, Mohammed Bencheqroun, Marc Vaillancourt, Mickael Calosso, Daniel Charpentier, Brian C. Wilkes, Gabrielle St-Pierre
Publikováno v:
ACS Medicinal Chemistry Letters. 3:1045-1049
The discovery of molecules that interfere with the binding of a ligand to a receptor remains a topic of great interest in medicinal chemistry. Herein, we report that a monosaccharide unit of a polysaccharide ligand can be replaced advantageously by a
Autor:
Michael White, Jeffrey R. Burton, Heather J. Ross, Marc Vaillancourt, R. Dorent, Jonathan G. Howlett, Haissam Haddad, Andrew Ignaszewski, Marcelo Cantarovich, Peter W. Pflugfelder
Publikováno v:
The Journal of Heart and Lung Transplantation. 27:197-202
Concentration-controlled everolimus with concomitant cyclosporine (CsA) dose reduction in renal transplantation permits preservation of kidney function without loss of efficacy. Data are lacking regarding everolimus with reduced-dose CsA in maintenan
Publikováno v:
Electroanalysis. 11:23-31
Nafion-glucose oxidase-ferrocene electrodes have been used to study the electron transfer between an electrode and the active site of the enzyme. These electrodes were prepared by casting a mixture of Nafion and glucose oxidase, GOx, (both dissolved
Autor:
Eric M, Yoshida, Leslie B, Lilly, Paul J, Marotta, Andrew L, Mason, Marc, Bilodeau, Marc, Vaillancourt
Publikováno v:
Annals of hepatology. 12(2)
The transition from regular use of cyclosporine to the newer calcineurin-inhibitors, such as tacrolimus, has been suggested as a contributing factor to the "era effect" of worsening outcomes of post-transplant HCV recurrence. This retrospective medic
Publikováno v:
Journal of Enzyme Inhibition. 9:217-233
The inhibitory behavior of simple N-protected amino acids containing a dysfunctional enol group was analyzed. Pseudo-Hill coefficients below 0.5 were obtained for the enol compounds. The active moiety of the enols described herein is involved in an e
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:343-355
A series of enol HIV-1 protease inhibitors which show competitive inhibition and the structure-activity relationship study which led to the design of these compounds are reported. By systematically modifying simple amino acids, Boc-Phe enol and Boc-T