Výsledky vyhledávání - "Marc V. Iversen"

Stereoselective Oxidative Bioconjugation of Amino Acids and Oligopeptides to Aldehydes

Autor: Henriette N. Tobiesen, Lars A. Leth, Marc V. Iversen, Line Næsborg, Søren Bertelsen, Karl Anker Jørgensen

Publikováno v: Tobiesen, H N, Leth, L A, Iversen, M V, Naesborg, L, Bertelsen, S & Jørgensen, K A 2020, ' Stereoselective Oxidative Bioconjugation of Amino Acids and Oligopeptides to Aldehydes ', Angewandte Chemie-International Edition, vol. 59, no. 42, pp. 18490-18494 . https://doi.org/10.1002/anie.202008513

The first stereoselective, near-equimolar, and metal-free oxidative bioconjugation of amino acids and oligopeptides to aldehydes is presented. Based on a newly developed organocatalytic oxidative concept, the C-terminal and side-chain carboxylic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ff85dca704c2e55a5f42056bd082be
https://doi.org/10.1002/anie.202008513

Zobrazit plný text záznamu

Stereoselective Oxidative Bioconjugation of Amino Acids and Oligopeptides to Aldehydes

Autor: Henriette N. Tobiesen, Karl Anker Jørgensen, Lars A. Leth, Marc V. Iversen, Line Næsborg, Søren Bertelsen

Publikováno v: Angewandte Chemie. 132:18648-18652

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcc55d975cac85f18cdd87152ec64d4d
https://doi.org/10.1002/ange.202008513

Zobrazit plný text záznamu

Plný text ve formátu HTML

A Direct Organocatalytic Enantioselective Route to Functionalized trans-Diels–Alder Products Having the Norcarane Scaffold

Autor: Karl Anker Jørgensen, Niklas Lawaetz Østergaard, Casper L. Barløse, Marc V. Iversen, René Slot Bitsch

Publikováno v: Barløse, C L, Østergaard, N L, Bitsch, R S, Iversen, M V & Jørgensen, K A 2021, ' A Direct Organocatalytic Enantioselective Route to Functionalized trans-Diels–Alder Products Having the Norcarane Scaffold ', Angewandte Chemie-International Edition, vol. 60, no. 33, pp. 18318-18327 . https://doi.org/10.1002/anie.202106598

An enantioselective methodology to construct trans-Diels–Alder scaffolds by organocatalysis with excellent selectivity, high yield and up to five contiguous stereocenters is presented. The reaction concept integrates the halogen effect and a novel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fdc3be3533e8567a966bd29946c4f2
https://pure.au.dk/portal/da/publications/a-direct-organocatalytic-enantioselective-route-to-functionalized-transdielsalder-products-having-the-norcarane-scaffold(1e357129-a6fc-44ca-b833-2be270153bb2).html

Zobrazit plný text záznamu

Umpolung Strategy for α-Functionalization of Aldehydes for the Addition of Thiols and other Nucleophiles

Autor: Matilde Rusbjerg, Jakob Blom, Casper L. Barløse, Karl Anker Jørgensen, Henriette N. Tobiesen, Marc V. Iversen, Niels Hammer, Gabriel J. Reyes-Rodríguez, Johannes N. Lamhauge

Publikováno v: Blom, J, Reyes Rodriguez, G J, Tobiesen, H N, Lamhauge, J N, Iversen, M V, Barløse, C L, Hammer, N, Rusbjerg, M & Jørgensen, K A 2019, ' Umpolung Strategy for α-Functionalization of Aldehydes for the Addition of Thiols and other Nucleophiles ', Angewandte Chemie-International Edition, vol. 58, no. 49, pp. 17856-17862 . https://doi.org/10.1002/anie.201911793

Nucleophile–nucleophile coupling is a challenging transformation in organic chemistry. Herein we present a novel umpolung strategy for α-functionalization of aldehydes with nucleophiles. The strategy uses organocatalytic enamine activation and qui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6637934f6e9d01618a42daf47b29a1e2
https://pure.au.dk/portal/da/publications/umpolung-strategy-for-functionalization-of-aldehydes-for-the-addition-of-thiols-and-other-nucleophiles(392d5730-182a-4517-8029-cd1380085d7f).html

Zobrazit plný text záznamu

Enantioselective Oxidative Coupling of Carboxylic Acids to α-Branched Aldehydes

Autor: Lars A. Leth, Gabriel J. Reyes-Rodríguez, Henriette N. Tobiesen, Line Næsborg, Marc V. Iversen, Karl Anker Jørgensen

Publikováno v: Leth, L A, Næsborg, L, Reyes-Rodríguez, G J, Tobiesen, H N, Iversen, M V & Jørgensen, K A 2018, ' Enantioselective Oxidative Coupling of Carboxylic Acids to α-Branched Aldehydes ', Journal of the American Chemical Society, vol. 140, no. 40, pp. 12687-12690 . https://doi.org/10.1021/jacs.8b07394

A new reactivity in organocatalysis is proposed to account for the coupling of carboxylic acids to α-branched aldehydes by combining primary amine catalysis and an oxidant. The developed methodology is an enantioselective α-coupling of aromatic and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf2b1f0954ac26edbb8762ffdfc3ad9
https://pure.au.dk/portal/da/publications/enantioselective-oxidative-coupling-of-carboxylic-acids-to-branched-aldehydes(d8d0d027-ad3a-454f-8f4a-7886a5f906bc).html

Zobrazit plný text záznamu

Directing the Activation of Donor-Acceptor Cyclopropanes Towards Stereoselective 1,3-Dipolar Cycloaddition Reactions by Brønsted Base Catalysis

Autor: Karl Anker Jørgensen, Jakob Blom, Marc V. Iversen, Julie Jørgensen, Casper L. Barløse, Kamilla S. Jessen, Andreu Vidal-Albalat

Publikováno v: Blom, J, Vidal-Albalat, A, Jørgensen, J, Barløse, C L, Jessen, K S, Iversen, M V & Jørgensen, K A 2017, ' Directing the Activation of Donor–Acceptor Cyclopropanes Towards Stereoselective 1,3-Dipolar Cycloaddition Reactions by Brønsted Base Catalysis ', Angewandte Chemie-International Edition, vol. 56, no. 39, pp. 11831-11835 . https://doi.org/10.1002/anie.201706150

The first stereoselective organocatalyzed [3+2] cycloaddition reaction of donor-acceptor cyclopropanes is presented. It is demonstrated that by applying an optically active bifunctional Brønsted base catalyst, racemic di-cyano cyclopropylketones can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0169c42b8da76ba4d397ecae7d64a564
https://pubmed.ncbi.nlm.nih.gov/28741849

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání