Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Marc Torrent Burgas"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 972-981 (2024)
Antimicrobial peptides (AMPs) are molecules found in most organisms, playing a vital role in innate immune defense against pathogens. Their mechanism of action involves the disruption of bacterial cell membranes, causing leakage of cellular contents
Externí odkaz:
https://doaj.org/article/9df23bbd2bf049c395bdde0352a4e4a1
Publikováno v:
eLife, Vol 13 (2024)
The study of protein interactions in living organisms is fundamental for understanding biological processes and central metabolic pathways. Yet, our knowledge of the bacterial interactome remains limited. Here, we combined gene deletion mutant analys
Externí odkaz:
https://doaj.org/article/cad1525341044aefb59b7c5bb8eebb5a
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6534-6542 (2022)
Protein-protein interactions (PPIs) are involved in most cellular processes. Unfortunately, current knowledge of host-pathogen interactomes is still very limited. Experimental methods used to detect PPIs have several limitations, including increasing
Externí odkaz:
https://doaj.org/article/a084f50964d34e92844249d20526d33c
Autor:
Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 4, Pp 1-20 (2019)
Abstract Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefi
Externí odkaz:
https://doaj.org/article/d4c0cd8793f240388d4a61302f5060a5
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008395 (2020)
Bacteria use protein-protein interactions to infect their hosts and hijack fundamental pathways, which ensures their survival and proliferation. Hence, the infectious capacity of the pathogen is closely related to its ability to interact with host pr
Externí odkaz:
https://doaj.org/article/c87f3d9b505b43359c132f2589620f3c
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Hubs tend to be essential for function in protein networks within organisms. Here, the authors show that during infection, it is the proteins with high centrality in theY. pestishost–pathogen interactome that are most important for pathogen fitness
Externí odkaz:
https://doaj.org/article/8e14028edd104ce1ba423ab6ea6636e1
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 354 (2021)
The rise in the number of antibiotic-resistant bacteria has become a serious threat to health, making it important to identify, characterize and optimize new molecules to help us to overcome the infections they cause. It is well known that Acinetobac
Externí odkaz:
https://doaj.org/article/1871b8e0b893405394b5446b6e558732
Publikováno v:
Microorganisms, Vol 7, Iss 9, p 292 (2019)
Localized infections or disruption of the skin barrier can enable the entry of bacteria into the bloodstream, possibly leading to acute inflammation and sepsis. There is currently no holistic view on how bacteria can survive and spread in the bloodst
Externí odkaz:
https://doaj.org/article/fb6f9733f0fb4655a4c51565a4054c8b
Autor:
Riccardo Delli Ponti, Laura Broglia, Andrea Vandelli, Alexandros Armaos, Marc Torrent Burgas, Natalia Sanchez de Groot, Gian Gaetano Tartaglia
RNA molecules undergo a number of chemical modifications whose effects can alter their structure and molecular interactions. Previous studies have shown that RNA editing can impact the formation of ribonucleoprotein complexes and influence the assemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec148c8352019a19480508dac7d96c5
https://doi.org/10.1101/2022.05.30.494057
https://doi.org/10.1101/2022.05.30.494057
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11489
Adhesion and colonization of host cells by pathogenic bacteria depend on protein–protein interactions (PPIs). These interactions are interesting from the pharmacological point of view since new molecules that inhibit host-pathogen PPIs would act as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530e5ae3853a081bec638cc6f66adeb2
https://ddd.uab.cat/record/267046
https://ddd.uab.cat/record/267046