Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Marc Tjwa"'
Autor:
Hiroto Iwasaki, Atsuhiko Kawamoto, Marc Tjwa, Miki Horii, Saeko Hayashi, Akira Oyamada, Tomoyuki Matsumoto, Shigefumi Suehiro, Peter Carmeliet, Takayuki Asahara
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24872 (2011)
Despite preclinical success in regenerating and revascularizing the infarcted heart using angiogenic growth factors or bone marrow (BM) cells, recent clinical trials have revealed less benefit from these therapies than expected.We explored the therap
Externí odkaz:
https://doaj.org/article/004d51c656d649998e8bcb5094d6a224
Autor:
Andrei Tintu, Ellen Rouwet, Stefan Verlohren, Joep Brinkmann, Shakil Ahmad, Fatima Crispi, Marc van Bilsen, Peter Carmeliet, Anne Cathrine Staff, Marc Tjwa, Irene Cetin, Eduard Gratacos, Edgar Hernandez-Andrade, Leo Hofstra, Michael Jacobs, Wouter H Lamers, Ingo Morano, Erdal Safak, Asif Ahmed, Ferdinand le Noble
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5155 (2009)
BACKGROUND:Intrauterine growth restriction is associated with an increased future risk for developing cardiovascular diseases. Hypoxia in utero is a common clinical cause of fetal growth restriction. We have previously shown that chronic hypoxia alte
Externí odkaz:
https://doaj.org/article/f94e4ab0c7db40d088273cfe1bd108d2
Autor:
Norbert Gerdes, Claudia M. van Tiel, Dorothee Atzler, Christian Weber, Myrthe E. Reiche, Hessel Poelman, Svenja Meiler, Marion J.J. Gijbels, Kikkie Poels, Marc Tjwa, Holger Winkels, Ulf Hedin, Gerry A. F. Nicolaes, Jan Albert Kuivenhoven, Pascal J. H. Kusters, Esther Lutgens, Bram Slütter, Gabrielle Paulsson-Berne, Tom Seijkens, Mat J.A.P. Daemen, Göran K. Hansson, Ljubica Perisic Matic, Johan Kuiper, Menno P.J. de Winther
Publikováno v:
European Heart Journal, 40(4), 372-382. Oxford University Press
European Heart Journal
European heart journal, 40(4), 372-382. Oxford University Press
European Heart Journal, 40(4), 372-382
European Heart Journal
European heart journal, 40(4), 372-382. Oxford University Press
European Heart Journal, 40(4), 372-382
The E3-ligase CBL-B (Casitas B-cell lymphoma-B) is an important negative regulator of T cell activation that is also expressed in macrophages. T cells and macrophages mediate atherosclerosis, but their regulation in this disease remains largely unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4978f299893c1e40724e63c0970b0814
https://cris.maastrichtuniversity.nl/en/publications/2543b105-5f1c-4b2b-a8c0-c39abd5f229e
https://cris.maastrichtuniversity.nl/en/publications/2543b105-5f1c-4b2b-a8c0-c39abd5f229e
Autor:
Peter Verhamme, Suzanne J.A. Korporaal, Roger van Kruchten, Reyhan Nergiz-Unal, Peter J. Voshol, Judith M.E.M. Cosemans, Susanne de Witt, Johan W. M. Heemskerk, Maria Febbraio, Marc Hoylaerts, Marc Tjwa, Marijke J.E. Kuijpers
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1187-1192. LIPPINCOTT WILLIAMS & WILKINS
Objective— Platelets abundantly express the membrane receptor CD36 and store its ligand thrombospondin-1 (TSP1) in the α-granules. We investigated whether released TSP1 can support platelet adhesion and thrombus formation via interaction with CD36
Autor:
Tom Seijkens, Menno P.J. de Winther, Esther Lutgens, Esther Smeets, Johannes H.M. Levels, Marc Tjwa, Svenja Meiler, Linda Beckers, Marten A. Hoeksema
Publikováno v:
FASEB journal, 28(5), 2202-2213. FASEB
Modulation of hematopoietic stem and progenitor cells (HSPCs) determines immune cell function. In this study, we investigated how hypercholesterolemia affects HSPC biology and atherosclerosis. Hypercholesterolemia induced loss of HSPC quiescence, cha
Autor:
Timothy Perera, Eric Angevin, Martin Forster, Glen Clack, Martijn P. Lolkema, Matthew G Krebs, Sarah P. Blagden, Elizabeth Ruth Plummer, Marc Tjwa, Filip de Vos, Ellen Jansen, Annegret Van der Aa, Eric Ciamporcero, Marion Libouban, Ann Meulemans
Publikováno v:
Journal of Clinical Oncology. 37:3062-3062
3062 Background: MET kinase is a therapeutic target in a range of cancer indications; it is a primary oncogenic driver and a mechanism of therapy resistance. OMO-1 is a highly potent, selective oral inhibitor of MET kinase and Organic Cation Transpor
Autor:
Marc Tjwa, Annegret Van der Aa, Glen Clack, Timothy Perera, Martijn P. Lolkema, Ann Meulemans, Marion Libouban, Eric Ciamporcero, Ellen Jansen
Publikováno v:
Journal of Clinical Oncology. 37:e14674-e14674
e14674 Background: The MET kinase is an established therapeutic target in a range of cancer indications, being a primary oncogenic and therapy resistance driver. Methods: OMO-1 is a highly potent, selective oral inhibitor of MET kinase and Organic Ca
Autor:
Jens Kroll, Eduard Hergenreider, Carmen Urbich, Sabine Gesierich, Tso-Pang Yao, Reinier A. Boon, Hellmut G. Augustin, Lothar Rössig, Andreas M. Zeiher, Edward Seto, Marc Tjwa, David Kaluza, Stefanie Dimmeler
Publikováno v:
The EMBO Journal. 30:4142-4156
Histone deacetylases (HDACs) deacetylate histones and non-histone proteins, thereby affecting protein activity and gene expression. The regulation and function of the cytoplasmic class IIb HDAC6 in endothelial cells (ECs) is largely unexplored. Here,
Autor:
Hans Kossmann, Sven Martens, Patrick Paulus, Rebekka Goetz, Janina Trauth, Giulio Cossu, Marc Tjwa, Masamichi Koyanagi, Stefanie Dimmeler, Kisho Ohtani, Kai Zacharowski, Andreas M. Zeiher, Masayoshi Iwasaki, Nadejda Monsefi, Stefan Rupp, Stefan Momma, Reinhard Henschler, Dietmar Schranz
Publikováno v:
European Heart Journal. 32:627-636
AIMS: The identification of factors that mobilize subsets of endogenous progenitor cells may provide new therapeutic tools to enhance the repair of ischaemic tissue. We previously identified circulating mesenchymal cells that co-express endothelial m
Publikováno v:
Thrombosis and Haemostasis, 104(4), 693-701. Georg Thieme Verlag
SummaryCD154 (CD40 ligand, CD40L, gp139) is a co-stimulatory molecule of the tumour necrosis factor (TNF) family. CD154 was originally discovered on T-cells, and was found to be involved in many immune responses including B-cell activation, isotype s