Výsledky vyhledávání - "Marc Terrones"

Akademický článek

CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles

Autor: Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)

Abstract Introduction The study of resistance-causing mutations in oncogene-driven tumors is fundamental to guide clinical decisions. Several point mutations affecting the ROS1 kinase domain have been identified in the clinical setting, but their imp

Externí odkaz: https://doaj.org/article/8badfa4b346b46089af6735007b9b043

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Pre-clinical modelling of ROS1+ non-small cell lung cancer

Autor: Marc Terrones, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer

Publikováno v: Lung cancer: journal of the International Association for the Study of Lung Cancer

Non-small cell lung cancer (NSCLC) is a heterogeneous group of diseases which accounts for 80% of newly diagnosed lung cancers. In the previous decade, a new molecular subset of NSCLC patients (around 2%) harboring rearrangements of the c-ros oncogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2aad5e40618bb8ee0f9721bb0288e4
https://repository.uantwerpen.be/docstore/d:irua:17550

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