A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant.

Autor: Ting Zhao, Lu Rui, Juan Li, Marc T Nishimura, John P Vogel, Na Liu, Simu Liu, Yaofei Zhao, Jeffery L Dangl, Dingzhong Tang

Publikováno v: PLoS Genetics, Vol 11, Iss 1, p e1004945 (2015)

During exocytosis, the evolutionarily conserved exocyst complex tethers Golgi-derived vesicles to the target plasma membrane, a critical function for secretory pathways. Here we show that exo70B1 loss-of-function mutants express activated defense res

Externí odkaz: https://doaj.org/article/838d7369d3814cd0b23752f949f483fb

Dynamic evolution of pathogenicity revealed by sequencing and comparative genomics of 19 Pseudomonas syringae isolates.

Autor: David A Baltrus, Marc T Nishimura, Artur Romanchuk, Jeff H Chang, M Shahid Mukhtar, Karen Cherkis, Jeff Roach, Sarah R Grant, Corbin D Jones, Jeffery L Dangl

Publikováno v: PLoS Pathogens, Vol 7, Iss 7, p e1002132 (2011)

Closely related pathogens may differ dramatically in host range, but the molecular, genetic, and evolutionary basis for these differences remains unclear. In many Gram- negative bacteria, including the phytopathogen Pseudomonas syringae, type III eff

Externí odkaz: https://doaj.org/article/8622e2c329a44048ab4c67da999a46b8

Broader functions of TIR domains in Arabidopsis immunity

Autor: Pierre Jacob, Junko Hige, Lijiang Song, Adam Bayless, Dor Russ, Vera Bonardi, Farid El Kasmi, Lisa Wünsch, Yu Yang, Connor R. Fitzpatrick, Brock J. McKinney, Marc T. Nishimura, Murray R. Grant, Jeffery L. Dangl

Publikováno v: Proceedings of the National Academy of Sciences. 120

TIR domains are NAD-degrading enzymes that function during immune signaling in prokaryotes, plants, and animals. In plants, most TIR domains are incorporated into intracellular immune receptors termed TNLs. In Arabidopsis, TIR-derived small molecules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084d77f959d78d9e07b5aa5e58f1aa4a
https://doi.org/10.1073/pnas.2220921120

Arabidopsis ADR1 helper NLR immune receptors localize and function at the plasma membrane in a phospholipid dependent manner

Autor: Svenja C. Saile, Marc T. Nishimura, Farid El Kasmi, Jutta Keicher, Vera Bonardi, Yvon Jaillais, Claudia Oecking, Eva Stöbbe, Li Wan, Jeffery L. Dangl, Frank M. Ackermann, Mehdi Doumane, Sruthi Sunil, Adam M. Bayless, Marie-Cécile Caillaud

Publikováno v: New Phytologist
New Phytologist, inPress, 232 (6), pp.2440-2456. ⟨10.1111/nph.17788⟩
New Phytologist, Wiley, In press, 232 (6), pp.2440-2456. ⟨10.1111/nph.17788⟩

International audience; Activation of nucleotide-binding leucine-rich repeat receptors (NLRs) results in immunity and a localized cell death. NLR cell death activity requires oligomerization and in some cases plasma membrane (PM) localization. The ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9593faeb244a9418c35d5f7e8bbb3e
https://doi.org/10.1111/nph.17788

TIR domains of plant immune receptors are NAD + -cleaving enzymes that promote cell death

Autor: Freddy Monteiro, Aaron DiAntonio, Li Wan, Ryan G. Anderson, Erin Osborne Nishimura, Marc T. Nishimura, Jeffrey Milbrandt, Kow Essuman, Yo Sasaki, Jeffery L. Dangl, Eui Hwan Chung

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors activate cell death and confer disease resistance by unknown mechanisms. We demonstrate that plant Toll/interleukin-1 receptor (TIR) domains of NLRs are enzymes capable of degrading

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b31bd9f0d0293958416af1f139536d
https://doi.org/10.1126/science.aax1771