Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Marc S Robillard"'
Autor:
Patricia E. Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Abdolreza Yazdani, Matthias Miederer, Andreas Kjær, John F. Valliant, Marc S. Robillard, Frank Rösch, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have bee
Externí odkaz:
https://doaj.org/article/3c3a2b2c7f3b4c0690ccc0893c5a719d
Autor:
Raffaella Rossin, Ron M. Versteegen, Jeremy Wu, Alisher Khasanov, Hans J. Wessels, Erik J. Steenbergen, Wolter ten Hoeve, Henk M. Janssen, Arthur H. A. M. van Onzen, Peter J. Hudson, Marc S. Robillard
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Current antibody-drug conjugates (ADCs) target internalising receptors on cancer cells. Here, the authors report the development and in vivo validation of a non-internalising ADC with the capacity to target cancer cells and release its therapeutic ca
Externí odkaz:
https://doaj.org/article/b6e9e26c80024b1e84795b448f5f9b65
Autor:
Bing Liu, Wolter ten Hoeve, Ron M Versteegen, Raffaella Rossin, Laurens HJ Kleijn, Marc S Robillard
Publikováno v:
Chemistry – A European Journal.
Autor:
Maria Vlastara, Raffaella Rossin, Freek J.M. Hoeben, Kim E. de Roode, Milou Boswinkel, Laurens H.J. Kleijn, James Nagarajah, Mark Rijpkema, Marc S. Robillard
One of the main challenges of PET imaging with89Zr-labeled monoclonal antibodies (mAbs) remains the long blood circulation of the radiolabeled mAbs, leading to high background signals, decreasing image quality. To overcome this limitation, here we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a39ab0e870fb6fd9c053ba4b6f6c098
https://doi.org/10.1101/2023.03.27.534155
https://doi.org/10.1101/2023.03.27.534155
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 12076-12092 (2015)
Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevate
Externí odkaz:
https://doaj.org/article/bf38a488e05949f1815201f0c9d00d92
Autor:
Raffaella Rossin, Ron M. Versteegen, Jeremy Wu, Alisher Khasanov, Hans J. Wessels, Erik J. Steenbergen, Wolter ten Hoeve, Henk M. Janssen, Arthur H. A. M. van Onzen, Peter J. Hudson, Marc S. Robillard
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article omitted the following from the Acknowledgements: ‘This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Breast Cancer Research Program under Award No. W81XWH
Externí odkaz:
https://doaj.org/article/fea92d6bbdb8481183adf2d4a9442582
Autor:
Jeremy Wu, Henk M. Janssen, Marc S. Robillard, Wolter ten Hoeve, Raffaella Rossin, Ivo A. W. Filot, Freek J. M. Hoeben, Tong Zhu, Ron M. Versteegen, Arthur H. A. M. van Onzen, Peter J. Hudson
Publikováno v:
Journal of the American Chemical Society, 142(25), 10955-10963. American Chemical Society
The high reaction rate of the 'click-to-release' reaction between allylic substituted trans-cyclooctene and tetrazine has enabled exceptional control over chemical and biological processes. Here we report the development of a new bioorthogonal cleava
Autor:
Samuel L. Scinto, Didier A. Bilodeau, Robert Hincapie, Wankyu Lee, Sean S. Nguyen, Minghao Xu, Christopher W. am Ende, M. G. Finn, Kathrin Lang, Qing Lin, John Paul Pezacki, Jennifer A. Prescher, Marc S. Robillard, Joseph M. Fox
Publikováno v:
Nature reviews. Methods primers, vol 1, iss 1
Nat Rev Methods Primers
Nat Rev Methods Primers
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed rapidly and selectively in biological environments without side reactions towards endogenous functional groups. Rooted in the principles of physical organic c
Autor:
Sylvestre Bonnet, Dmitri V. Filippov, Sander I. van Kasteren, Jeroen D. C. Codée, Herman S. Overkleeft, Max S. Kloet, Kiki Kamphorst, Marc S. Robillard, Elmer Maurits, Mark A. R. de Geus, Andrea Pannwitz, Alexi J. C. Sarris, Wolter ten Hoeve, Thomas Hansen
Publikováno v:
de Geus, M A R, Maurits, E, Sarris, A J C, Hansen, T, Kloet, M S, Kamphorst, K, ten Hoeve, W, Robillard, M S, Pannwitz, A, Bonnet, S A, Codée, J D C, Filippov, D V, Overkleeft, H S & van Kasteren, S I 2020, ' Fluorogenic Bifunctional trans-Cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics ', Chemistry-A European Journal, vol. 26, no. 44, pp. 9900-9904 . https://doi.org/10.1002/chem.201905446
Chemistry-A European Journal, 26(44), 9900-9904. Wiley-VCH Verlag
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry – A European Journal
Chemistry-a European Journal, 26(44), 9900-9904
Chemistry-A European Journal, 26(44), 9900-9904. Wiley-VCH Verlag
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry – A European Journal
Chemistry-a European Journal, 26(44), 9900-9904
The inverse electron demand Diels–Alder pyridazine elimination reaction between tetrazines and allylic substituted trans‐cyclooctenes (TCOs) is a key player in bioorthogonal bond cleavage reactions. Determining the rate of elimination of alkylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2934b0805fc36e3b284866a7c8515227
https://research.vu.nl/en/publications/c62a99a8-a2c4-41e0-8633-309843ad9529
https://research.vu.nl/en/publications/c62a99a8-a2c4-41e0-8633-309843ad9529
Autor:
Arthur H A M, van Onzen, Ron M, Versteegen, Freek J M, Hoeben, Ivo A W, Filot, Raffaella, Rossin, Tong, Zhu, Jeremy, Wu, Peter J, Hudson, Henk M, Janssen, Wolter, Ten Hoeve, Marc S, Robillard
Publikováno v:
Journal of the American Chemical Society. 142(25)
The high rate of the 'click-to-release' reaction between an allylic substituted