Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Marc S, Penn"'
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Objective Diabetes is a risk equivalent for cardiovascular events. The increase in vascular inflammation with diabetes is believed to be responsible for increased risk of ischemic events in diabetic patients. Our goal was to assess whether knowledge
Externí odkaz:
https://doaj.org/article/6b93c15a292447dfba8664d5241e2337
Autor:
Ruth S. Weinstock, Bruce W. Bode, Satish K. Garg, David C. Klonoff, Caroline El Sanadi, W. Blair Geho, Douglas B. Muchmore, Marc S. Penn
Publikováno v:
Diabetes, Obesity and Metabolism. 24:1762-1769
To investigate whether an increased bolus: basal insulin ratio (BBR) with liver-targeted bolus insulin (BoI) would increase BoI use and decrease hypoglycaemic events (HEv).We enrolled 52 persons (HbA1c 6.9% ± 0.12%, mean ± SEM) with type 1 diabetes
Publikováno v:
Circulation. 144
Background: High blood levels of free myeloperoxidase (MPO) identify patients at risk for cardiovascular disease. We investigated levels of MPO according to 10-year ASCVD risk and the association between high MPO and markers of liver fibrosis and kid
Autor:
Charuspong Dissaranan, Michelle A. Cruz, Matthew J. Kiedrowski, Brian M. Balog, Bradley C. Gill, Marc S. Penn, Howard B. Goldman, Margot S. Damaser Ph.D.
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Vaginal delivery is a risk factor for stress urinary incontinence (SUI). Mesenchymal stem cells (MSCs) home to injured organs and can facilitate repair. The goal of this study was to determine if MSCs home to pelvic organs after simulated childbirth
Externí odkaz:
https://doaj.org/article/d54e4540886e45a3bbc88cd2415207ec
Publikováno v:
Journal of Alzheimer's Disease
Porphyromonas gingivalis (Pg) is a primary oral pathogen in the widespread biofilm-induced “chronic” multi-systems inflammatory disease(s) including Alzheimer’s disease (AD). It is possibly the only second identified unique example of a biologi
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68528 (2013)
Stage specific embryonic antigen 1+ (SSEA1+) cells have been described as the most primitive mesenchymal progenitor cell in the bone marrow. Cardiac injury mobilizes SSEA1+ cells into the peripheral blood but their in vivo function has not been chara
Externí odkaz:
https://doaj.org/article/ec371f6608d84690bdee3ba52922f098
Autor:
Marc S. Penn, Bruce W. Bode, Walter Geho, Kamalpreet K. Singh, Douglas B. Muchmore, Ruth S. Weinstock, Satish K. Garg, Caroline E. El Sanadi, David C. Klonoff
Publikováno v:
Diabetes. 69
Background: Subcutaneous (SC) insulin is non-physiologic, since normally insulin is secreted into the portal vein going directly to the liver. The OPTI-1 study was designed to determine whether delivery of Hepatic Directed Vesicles (HDV) admixed with
Autor:
Adonis Hijaz, Amr Mahran, Marc S. Penn, Juliana Woda, Ilaha Isali, Michael Kavran, Christopher A Flask, Ahmad O. Khalifa
Publikováno v:
International Urogynecology Journal. 31:107-115
SDF-1 chemokine enhances tissue regeneration through stem cell chemotaxis, neovascularization and neuronal regeneration. We hypothesized that non-viral delivery of human plasmids that express SDF-1 (pSDF-1) may represent a novel regenerative therapy
Autor:
Satish Medicetty, Dominik Wiktor, Nicholas Lehman, Amy Raber, Zoran B. Popovic, Robert Deans, Anthony E. Ting, Marc S. Penn M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Acute myocardial infarction (AMI) results in ischemic damage and death of cardiomyocytes and loss of vasculature. Stem cell therapy has emerged as a potentially promising strategy for maximizing cardiac function following ischemic injury. Issues of c
Externí odkaz:
https://doaj.org/article/9a6ade1f35ce43a5918fae84016711cb
Autor:
Kenya Kusunose, Marc S Penn, Youhua Zhang, Yuanna Cheng, James D Thomas, Thomas H Marwick, Zoran B Popović
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40061 (2012)
BackgroundWhile mammalian heart size maintains constant proportion to whole body size, scaling of left ventricular (LV) function parameters shows a more complex scaling pattern. We used 2-D speckle tracking strain imaging to determine whether LV myoc
Externí odkaz:
https://doaj.org/article/afdb9eaa9ba64393abbbf7bbe8e887cb