Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marc Ruiz-Martinez"'
Autor:
Yu Muta, Juan F. Linares, Anxo Martinez-Ordoñez, Angeles Duran, Tania Cid-Diaz, Hiroto Kinoshita, Xiao Zhang, Qixiu Han, Yuki Nakanishi, Naoko Nakanishi, Thekla Cordes, Gurpreet K. Arora, Marc Ruiz-Martinez, Miguel Reina-Campos, Hiroaki Kasashima, Masakazu Yashiro, Kiyoshi Maeda, Ana Albaladejo-Gonzalez, Daniel Torres-Moreno, José García-Solano, Pablo Conesa-Zamora, Giorgio Inghirami, Christian M. Metallo, Timothy F. Osborne, Maria T. Diaz-Meco, Jorge Moscat
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The metabolic and signaling pathways regulating aggressive mesenchymal colorectal cancer (CRC) initiation and progression through the serrated route are largely unknown. Although relatively well characterized as BRAF mutant cancers, their po
Externí odkaz:
https://doaj.org/article/7936ce2ec8a04c66b79574c289fddb37
Autor:
Wenbin An, Maria Feola, Maayan Levy, Srinivas Aluri, Marc Ruiz-Martinez, Ashwin Sridharan, Eitan Fibach, Xiaofan Zhu, Amit Verma, Yelena Ginzburg
Publikováno v:
eLife, Vol 12 (2023)
Myelodysplastic syndrome (MDS) is a heterogeneous group of bone marrow stem cell disorders characterized by ineffective hematopoiesis and cytopenias, most commonly anemia. Red cell transfusion therapy for anemia in MDS results in iron overload, corre
Externí odkaz:
https://doaj.org/article/cedb8c13ba2d4398bcc5cae9fdd1bb2a
Autor:
Melanie Castro-Mollo, Sakshi Gera, Marc Ruiz-Martinez, Maria Feola, Anisa Gumerova, Marina Planoutene, Cara Clementelli, Veena Sangkhae, Carla Casu, Se-Min Kim, Vaughn Ostland, Huiling Han, Elizabeta Nemeth, Robert Fleming, Stefano Rivella, Daria Lizneva, Tony Yuen, Mone Zaidi, Yelena Ginzburg
Publikováno v:
eLife, Vol 10 (2021)
Background: Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis. Methods: To address whether ERFE functions
Externí odkaz:
https://doaj.org/article/a63d104b3d4442358089c7d732e41650
Autor:
Wenbin An, Maria Feola, Srinivas Aluri, Marc Ruiz-Martinez, Ashwin Shridharan, Maayan Levy, Eitan Fibach, Xiaofan Zhu, Amit Verma, Yelena Z. Ginzburg
Myelodysplastic syndrome (MDS) is a heterogeneous group of bone marrow stem cell disorders characterized by ineffective hematopoiesis and cytopenias, most commonly anemia. Red cell transfusion therapy for anemia in MDS results in iron overload, corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4536c9547e5701df06440f42315146b2
https://doi.org/10.1101/2022.10.05.510967
https://doi.org/10.1101/2022.10.05.510967
Autor:
Anxo, Martinez-Ordoñez, Angeles, Duran, Marc, Ruiz-Martinez, Tania, Cid-Diaz, Xiao, Zhang, Qixiu, Han, Hiroto, Kinoshita, Yu, Muta, Juan F, Linares, Hiroaki, Kasashima, Yuki, Nakanishi, Mohamed, Omar, Sadaaki, Nishimura, Leandro, Avila, Masakazu, Yashiro, Kiyoshi, Maeda, Tania, Pannellini, Alessio, Pigazzi, Giorgio, Inghirami, Luigi, Marchionni, Darren, Sigal, Maria T, Diaz-Meco, Jorge, Moscat
Publikováno v:
Cancer Cell. 41:252-271.e9
Mesenchymal colorectal cancer (mCRC) is microsatellite stable (MSS), highly desmoplastic, with CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f629d024a1e2d0c07f8886fa2fad176
https://doi.org/10.1016/j.ccell.2022.11.016
https://doi.org/10.1016/j.ccell.2022.11.016
Autor:
Sakshi Gera, Marina Planoutene, Melanie Castro-Mollo, Mone Zaidi, Cara Clementelli, Robert E. Fleming, Se-Min Kim, Elizabeta Nemeth, Tony Yuen, Carla Casu, Vaughn Ostland, Stefano Rivella, Yelena Ginzburg, Huiling Han, Anisa Gumerova, Daria Lizneva, Maria Feola, Veena Sangkhae, Marc Ruiz-Martinez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d244e8c6a88459befbfb179ee006f4b
https://doi.org/10.7554/elife.68217.sa2
https://doi.org/10.7554/elife.68217.sa2
Autor:
Nathan Brinkman, Andrea Zamperone, Tenzin Choesang, Ronald Hoffman, Christopher E. Mason, Marc Ruiz Martinez, Carla Casu, Matthew MacKay, Mansour Djedaini, Jose Javier Bravo-Cordero, Dechen Lama, Luena Papa, Yelena Ginzburg, Paul Zumbo, Daniel Moskop, Peng Ji, Julie Di Martino, Stefano Rivella, Maria Feola, Shilpa M. Hattangadi, Huiyong Chen, Charles S. Abrams, Antonia Follenzi
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Erythropoiesis involves complex interrelated molecular signals influencing cell survival, differentiation, and enucleation. Diseases associated with ineffective erythropoiesis, such as β-thalassemias, exhibit erythroid expansion and defective enucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9133d58181c41c673c499a42311b7cf
https://doi.org/10.1038/s42003-021-02046-9
https://doi.org/10.1038/s42003-021-02046-9
Autor:
Huiling Han, Se-Min Kim, Vaughn Ostland, Maria Feola, Elizabeta Nemeth, Marc Ruiz-Martinez, Daria Lizneva, Melanie Castro-Mollo, Sakshi Gera, Anisa Gumerova, Marina Planoutene, Cara Clementelli, Carla Casu, Stefano Rivella, Mone Zaidi, Veena Sangkhae, Robert E. Fleming, Tony Yuen, Yelena Ginzburg
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Background:Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis.Methods:To address whether ERFE functions al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41c6fdf3686de36b695112620e58079
https://elifesciences.org/articles/68217
https://elifesciences.org/articles/68217
Autor:
Vaughn Ostland, Mone Zaidi, Veena Sangkhae, Elizabeta Nemeth, Tony Yuen, Maria Feola, Melanie Castro-Mollo, Marc Ruiz Martinez, Sakshi Gera, Robert E. Fleming, Anisa Gumerova, Carla Casu, Stefano Rivella, Marina Planoutene, Yelena Ginzburg, Huiling Han, Se-Min Kim, Cara Clementelli, Daria Lizneva
Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis. We report that ERFE expression in osteoblasts is highe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ada268b25caf1070f2f0ead039d06fa
https://doi.org/10.1101/2021.04.09.439174
https://doi.org/10.1101/2021.04.09.439174
Autor:
Vaughn Ostland, Eileen Westerman, Yelena Ginzburg, Gordana Olbina, Tomas Ganz, Elizabeta Nemeth, Huiling Han, Keith Westerman, Marc Ruiz Martinez, Patrick Gutschow
Publikováno v:
Blood. 134:2237-2237
Erythroferrone (ERFE) is a hormone produced by erythroblasts in response to erythropoietin. ERFE acts as a regulator of hepcidin expression during stress erythropoiesis. By suppressing hepcidin expression, ERFE contributes to the mobilization of diet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f4745cd39542099ab9583c6c4d0fcd
https://doi.org/10.1182/blood-2019-130947
https://doi.org/10.1182/blood-2019-130947