Výsledky vyhledávání - "Marc Ruitenberg"

MEDB-06. Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that loss of heterogeneity and induced differentiation underlies the response to CDK4/6 inhibition

Autor: Tuan Vo, Brad Balderson, Kahli Jones, Joanna Crawford, Amanda Millar, Elissa Tolson, Marc Ruitenberg, Thomas Robertson, Dharmesh Bhuva, Melissa Davis, Brandon Wainwright, Quan Nguyen, Laura Genovesi

Publikováno v: Neuro-Oncology. 24:i105-i105

Medulloblastoma (MB) is a malignant tumour of the cerebellum which can be classified into four major subgroups on the basis of gene expression and genomic features. Single cell transcriptome studies have defined the cellular states underlying each MB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aed683610644f5873a0fb7569e422690
https://doi.org/10.1093/neuonc/noac079.381

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Semaphorins and their receptors in olfactory axon guidance

Autor: Pasterkamp, R. J., Marc Ruitenberg, Verhaagen, J.

Publikováno v: Cellular and Molecular Biology, 45(6), 763-779. Cellular and Molecular Biology Association
Pasterkamp, R J, Ruitenberg, M J & Verhaagen, J 1999, ' Semaphorins and their receptors in olfactory axon guidance ', Cellular and Molecular Biology, vol. 45, no. 6, pp. 763-779 .
Europe PubMed Central
Scopus-Elsevier

The mammalian olfactory system is capable of discriminating among a large variety of odor molecules and is therefore essential for the identification of food, enemies and mating partners. The assembly and maintenance of olfactory connectivity have be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::47a33d9660b522414a360c267859d7f8
https://hdl.handle.net/1871.1/ec3d7c98-0e74-4819-9609-4d923c6dd5a9

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Akademický článek

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Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system

Autor: Alan R, Harvey, Erich, Ehlert, Joris, de Wit, Eleanor S, Drummond, Margaret A, Pollett, Marc, Ruitenberg, Giles W, Plant, Joost, Verhaagen, Christiaan N, Levelt

Publikováno v: Methods in molecular biology (Clifton, N.J.). 515

We here describe various approaches using GFP that are being used in the morphological and functional analysis of specific cell types in the normal and injured central nervous system. Incorporation of GFP into viral vectors allows phenotypic characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3dbc935189291c21e743c8808bbfc46
https://pubmed.ncbi.nlm.nih.gov/19378117

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Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord

Autor: Marc Ruitenberg, Plant, G. W., Hamers, F. P. T., Wortel, J., Blits, B., Dijkhuizen, P. A., Gispen, W. H., Boer, G. J., Verhaagen, J.

Publikováno v: The journal of neuroscience, 23(18), 7045. Society for Neuroscience
Scopus-Elsevier
Ruitenberg, M J, Plant, G W, Hamers, F P T, Wortel, J, Blits, B, Dijkhuizen, P A, Gispen, W H, Boer, G J & Verhaagen, J 2003, ' Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: Effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord ', The Journal of Neuroscience, vol. 23, no. 18, pp. 7045-7058 .
The Journal of Neuroscience, 23(18), 7045-7058. Society for Neuroscience

The present study uniquely combines olfactory ensheathing glia (OEG) implantation with ex vivo adenoviral (AdV) vector-based neurotrophin gene therapy in an attempt to enhance regeneration after cervical spinal cord injury. Primary OEG were transduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ded9448c6fe4aa82a5ec9e084daff036
https://dspace.library.uu.nl/handle/1874/3759

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In vitro generated human microglia derived from blood precursors (111.14)

Autor: Samar Etemad, Marc Ruitenberg, Luis Filgueira

Publikováno v: The Journal of Immunology. 188:111.14-111.14

Microglia as the resident innate immune cells of the brain share common characteristics with monocyte-macrophage lineage such as expression of surface markers and chemokine/cytokine receptors. To date, there is no standardized simple model available

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea3638beac4d6d88121e53e6ef6c5076
https://doi.org/10.4049/jimmunol.188.supp.111.14

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