Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marc Rico Pasto"'
Autor:
Marc Rico-Pasto, Felix Ritort
Publikováno v:
Biophysica, Vol 3, Iss 3, Pp 539-547 (2023)
Detecting conformational transitions in molecular systems is key to understanding biological processes. Here, we investigate the force variance in single-molecule pulling experiments as an indicator of molecular folding transitions. We consider cases
Externí odkaz:
https://doaj.org/article/38fdb466487e426fb4e91c5e977f0774
Autor:
Marc Rico-Pasto, Felix Ritort
Publikováno v:
Biophysical Reports, Vol 2, Iss 3, Pp 100067- (2022)
Knowledge of the elastic properties, e.g., the persistence length or interphosphate distance, of single-stranded (ss) and double-stranded (ds) DNA under different experimental conditions is critical to characterizing molecular reactions studied with
Externí odkaz:
https://doaj.org/article/67e54e28ed4e4de69e649fe02b417f08
Publikováno v:
Entropy, Vol 24, Iss 7, p 895 (2022)
Nonequilibrium work relations and fluctuation theorems permit us to extract equilibrium information from nonequilibrium measurements. They find application in single-molecule pulling experiments where molecular free energies can be determined from ir
Externí odkaz:
https://doaj.org/article/4a1cab7184fa4fdd98090b2f81e3d80a
Publikováno v:
Nanomaterials, Vol 11, Iss 11, p 3023 (2021)
Single-molecule force spectroscopy has opened a new field of research in molecular biophysics and biochemistry. Pulling experiments on individual proteins permit us to monitor conformational transitions with high temporal resolution and measure their
Externí odkaz:
https://doaj.org/article/60a415672b234cb6b866377221b85b32
Autor:
Regina K. Schmitt, Patrick P. Potts, Heiner Linke, Jonas Johansson, Peter Samuelsson, Marc Rico-Pasto, Felix Ritort
Publikováno v:
Physical Review E. 107
We theoretically investigate the extractable work in single molecule unfolding-folding experiments with applied feedback. Using a simple two-state model, we obtain a description of the full work distribution, from discrete to continuous feedback. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d850bdd221f695ec72f832ebc127a527
https://doi.org/10.1103/physreve.107.l052104
https://doi.org/10.1103/physreve.107.l052104
Publikováno v:
Journal of Physical Chemistry Letters, 13(4), 1025-1032. AMER CHEMICAL SOC
Most single-molecule studies derive the kinetic rates of native, intermediate, and unfolded states from equilibrium hopping experiments. Here, we apply Kramers kinetic diffusive model to derive the force-dependent kinetic rates of intermediate states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfeac589d19356f72aaf3de74f2ef42
https://doi.org/10.1021/acs.jpclett.1c03521
https://doi.org/10.1021/acs.jpclett.1c03521
The experimental measurement of correlation functions and critical exponents in disordered systems is key to testing renormalization group (RG) predictions. We mechanically unzip single DNA hairpins with optical tweezers, an experimental realization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3b3d40a580cda241f0d2e576266e08
http://arxiv.org/abs/2210.00777
http://arxiv.org/abs/2210.00777
Publikováno v:
Entropy; Volume 24; Issue 7; Pages: 895
Nonequilibrium work relations and fluctuation theorems permit us to extract equilibrium information from nonequilibrium measurements. They find application in single-molecule pulling experiments where molecular free energies can be determined from ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d5d985e89cd8314d5d48244bc76aa0
https://pubmed.ncbi.nlm.nih.gov/35885118
https://pubmed.ncbi.nlm.nih.gov/35885118
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Understanding how proteins fold into their native structure is a fundamental problem in biophysics, crucial for protein design. It has been hypothesized that the formation of a molten globule intermediate precedes folding to the native conformation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7726e46fdc62368a8752bb3af8f334a0
https://doi.org/10.1073/pnas.2112382119
https://doi.org/10.1073/pnas.2112382119
Autor:
Hagan Bayley, Jannes Gladrow, Felix Ritort, Anatoly B. Kolomeisky, Yujia Qing, Alice L. Thorneywork, Marc Rico-Pasto, Ulrich F. Keyser
Publikováno v:
Science Advances
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Model-free method reveals details of underlying energy landscapes from dynamics in experimental systems across a range of scales.
All natural phenomena are governed by energy landscapes. However, the direct measurement of this fundamental quanti
All natural phenomena are governed by energy landscapes. However, the direct measurement of this fundamental quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23af3606ffcb1fd97164515dff9c70b0
https://doi.org/10.1126/sciadv.aaz4642
https://doi.org/10.1126/sciadv.aaz4642