Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marc R. Peterson"'
Autor:
Philip A. Wornell, Marc R. Peterson, Frank J. Gonzalez, Matthew G. Blanchard, Theresa C. Peterson
Publikováno v:
Biochemical Pharmacology. 68:395-402
In this study the drug interaction between ciprofloxacin (CIPRO) and pentoxifylline (PTX) was investigated and the role of CYP1A2 in the drug interaction was determined with the aid of a selective CYP1A2 inhibitor, furafylline (FURA), and the Cyp1A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cffee45c346fa99d091839a57f9dbf
https://doi.org/10.1016/j.bcp.2004.03.035
https://doi.org/10.1016/j.bcp.2004.03.035
Publikováno v:
Molecular Pharmacology. 61:1476-1488
Platelet-derived growth factor (PDGF) signals through several pathways, including mitogen-activated protein (MAP) kinase, Jun kinase, and C kinase, and stimulates proliferation of fibroblasts. Pentoxifylline inhibits PDGF-driven proliferation of fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f5f607f81c085c4cfdf56a9ee144dc
https://doi.org/10.1124/mol.61.6.1476
https://doi.org/10.1124/mol.61.6.1476
Publikováno v:
European journal of pharmacology. 662(1-3)
TNBS-induced colitis has characteristics resembling human Crohn's disease including transmural inflammation, ulceration, and fibrosis. Current treatments target acute symptoms but do not necessarily prevent fibrotic complications of the disease. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226927afe99662a0d764cde6bdc7dfc2
https://pubmed.ncbi.nlm.nih.gov/21554874
https://pubmed.ncbi.nlm.nih.gov/21554874
Publikováno v:
Biochemical pharmacology. 74(4)
Pentoxifylline (PTX), a methylxanthine derivative, is metabolized to seven compounds in vivo, with metabolites 1 and 5 possessing biologic activity. Metabolite-1 is a chiral molecule and its S-enantiomer is selectively formed during PTX metabolism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c059085a720a49aaaf05379aca80c535
https://pubmed.ncbi.nlm.nih.gov/17599808
https://pubmed.ncbi.nlm.nih.gov/17599808
Publikováno v:
European journal of pharmacology. 572(2-3)
We have previously shown that monocyte conditioned medium (MCM) from patients with liver fibrosis stimulated proliferation of hepatic stellate cells (HSCs), the major cell involved in hepatic fibrosis. To investigate the potential role of fetuin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6871665ce1b8a81e9ca1df5dcb2014cd
https://pubmed.ncbi.nlm.nih.gov/17678645
https://pubmed.ncbi.nlm.nih.gov/17678645
Publikováno v:
Neurobiology of Aging. 21:98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::013465eadb8ce182b660e2acee076c4a
https://doi.org/10.1016/s0197-4580(00)82665-2
https://doi.org/10.1016/s0197-4580(00)82665-2
Publikováno v:
Toxicology and Applied Pharmacology. 97:430-439
Administration of cysteamine to rats depressed hepatic aryl hydrocarbon hydroxylase (AHH) activity, cytochrome P-450, and total heme at 24 hr. Total heme remained decreased at 48 hr when all other parameters returned to control values. A significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a176f1e3424a7e041c2922a2c14f03
https://doi.org/10.1016/0041-008x(89)90248-2
https://doi.org/10.1016/0041-008x(89)90248-2
Publikováno v:
European Journal of Pharmacology. 135:113-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe78baa3122da73eab91bc95e339c7be
https://doi.org/10.1016/0014-2999(87)90767-9
https://doi.org/10.1016/0014-2999(87)90767-9