Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marc R. Bornstein"'
Autor:
Froukje Vanweert, Michael Neinast, Edmundo Erazo Tapia, Tineke van de Weijer, Joris Hoeks, Vera B. Schrauwen-Hinderling, Megan C. Blair, Marc R. Bornstein, Matthijs K. C. Hesselink, Patrick Schrauwen, Zoltan Arany, Esther Phielix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Evidence from preclinical models suggest that lowering levels of branched chain amino acids (BCAA) improves glucose metabolism. Here the authors report that NaPB, an accelerator of BCAA catabolism, improves peripheral insulin sensitivity in patients
Externí odkaz:
https://doaj.org/article/13e10d35d6bc4308a78288bcc1294944
Autor:
Megan C. Blair, Michael D. Neinast, Cholsoon Jang, Qingwei Chu, Jae Woo Jung, Jessie Axsom, Marc R. Bornstein, Chelsea Thorsheim, Kristina Li, Atsushi Hoshino, Steven Yang, Rachel J. Roth Flach, Bei B. Zhang, Joshua D. Rabinowitz, Zoltan Arany
Publikováno v:
Nature Metabolism. 5:589-606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6262b07e528909e5110666cf8a4b8046
https://doi.org/10.1038/s42255-023-00794-y
https://doi.org/10.1038/s42255-023-00794-y
Autor:
Bridget S. Gosis, Shogo Wada, Chelsea Thorsheim, Kristina Li, Sunhee Jung, Joshua H. Rhoades, Yifan Yang, Jeffrey Brandimarto, Li Li, Kahealani Uehara, Cholsoon Jang, Matthew Lanza, Nathan B. Sanford, Marc R. Bornstein, Sunhye Jeong, Paul M. Titchenell, Sudha B. Biddinger, Zoltan Arany
Publikováno v:
Science (New York, N.Y.), vol 376, iss 6590
Science
Science
INTRODUCTION: As many as 100 million people in the US have nonalcoholic fatty liver disease (NAFLD), characterized by increased liver lipid accumulation, which often leads to hepatocyte injury and fibrosis, characteristics of nonalcoholic steatohepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0008f289f900d9b441ca79f71ac969
https://escholarship.org/uc/item/1pq143rx
https://escholarship.org/uc/item/1pq143rx
Autor:
Froukje Vanweert, Michael D. Neinast, Patrick Schrauwen, Joris Hoeks, Zoltan Arany, Matthijs K.C. Hesselink, Marc R. Bornstein, Edmundo Erazo Tapia, Tineke van de Weijer, Esther Phielix, Vera B. Schrauwen-Hinderling, Megan C. Blair
Publikováno v:
SSRN Electronic Journal.
Background: Elevations in plasma branched-chain amino acid (BCAA) levels associate with insulin resistance and type 2 diabetes (T2D). Pre-clinical models have suggested that lowering BCAA levels improve glucose tolerance, but data in humans are lacki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ac97383bfcc1520e019f1a43c0c838
https://doi.org/10.2139/ssrn.3944597
https://doi.org/10.2139/ssrn.3944597
Autor:
Paul A. Oliphint, Melanie R. McReynolds, Mu Jie Lu, Mathias Ziegler, F. Brad Johnson, Lin Wang, Kai Johnsson, Caroline Perry, Fabio Raith, Marc R. Bornstein, Marc Niere, Jared M. Eller, Marie E. Migaud, Xiaolu A. Cambronne, Timothy S. Luongo, Joseph A. Baur, Joshua D. Rabinowitz
Publikováno v:
Nature
174–179
174–179
Mitochondria require nicotinamide adenine dinucleotide (NAD+) to carry out the fundamental processes that fuel respiration and mediate cellular energy transduction. Mitochondrial NAD+ transporters have been identified in yeast and plants1,2, but thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff60d433a63f58be91e5a36f3136f186
https://hdl.handle.net/11250/2753314
https://hdl.handle.net/11250/2753314
Autor:
Marc R. Bornstein, John J. Ferrie, Zachary M Hostetler, Itthipol Sungwienwong, E. James Petersson, Rahul M. Kohli
Publikováno v:
ACS chemical biology. 13(10)
Improvements in genetic code expansion have made preparing proteins with diverse functional groups almost routine. Nonetheless, unnatural amino acids (Uaas) pose theoretical burdens on protein solubility, and determinants of position-specific tolerab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d49ce3c8567633026a6a95fdf1b6ac2
https://pubmed.ncbi.nlm.nih.gov/30216041
https://pubmed.ncbi.nlm.nih.gov/30216041