Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marc Q. Mazzuca"'
Publikováno v:
Biochemical pharmacology. 208
Preeclampsia is a pregnancy-related hypertensive disorder (HTN-Preg) with unclear mechanisms. We have shown increased vascular reactivity to extrinsic vasoconstrictors in HTN-Preg rats. Here, we test whether microvascular intrinsic tone and arterial
Publikováno v:
Biochemical Pharmacology. 208:115353
Autor:
Sarah L. Walton, Mary E. Wlodek, Helena C. Parkington, Marianne Tare, Karen M. Moritz, Marc Q. Mazzuca, Linda A. Gallo
Publikováno v:
The Journal of Physiology. 596:5859-5872
KEY POINTS: Low weight at birth increases the risk of developing chronic diseases in adulthood A diet that is high in salt is known to elevate blood pressure, which is a major risk factor for cardiovascular and kidney diseases The present study demon
Autor:
Helena C. Parkington, Marianne Tare, Sarah L. Walton, Marc Q. Mazzuca, Karen M. Moritz, Mary E. Wlodek, Linda A. Gallo
Publikováno v:
Pharmacological research. 134
Inhibition of the renin-angiotensin system in early postnatal life is a potential therapeutic approach to prevent long-term cardiovascular and kidney diseases in individuals born small. We determined the long-term effects of juvenile losartan treatme
Autor:
Linda A, Gallo, Sarah L, Walton, Marc Q, Mazzuca, Marianne, Tare, Helena C, Parkington, Mary E, Wlodek, Karen M, Moritz
Publikováno v:
The Journal of physiology. 596(23)
KEY POINTS: Low weight at birth increases the risk of developing chronic diseases in adulthood. A diet that is high in salt is known to elevate blood pressure, which is a major risk factor for cardiovascular and kidney diseases. The present study dem
Autor:
Marc Q. Mazzuca, Raquel F. Gerlach, Cleverson Rodrigues Fernandes, Elaine M. Floriano, Cristiane Tefé-Silva, Simone G. Ramos, Elen Rizzi, Karina M. Mata
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Abdominal aortic aneurysm (AAA) is characterized by chronic inflammation and degradation of the extracellular matrix, mediated by matrix metalloproteinases (MMPs). Doxycycline has been reported to control the progression of AAA by regulati
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 313(3)
Preeclampsia is a pregnancy-related disorder manifested as maternal hypertension in pregnancy (HTN-Preg) and fetal growth restriction. Placental ischemia could be an initiating event that leads to abnormal vascular and uteroplacental remodeling in HT
Publikováno v:
Hypertension. 64:632-643
Preeclampsia is a pregnancy-related disorder characterized by hypertension with an unclear mechanism. Studies have shown endothelial dysfunction and increased endothelin-1 (ET-1) levels in hypertensive pregnancy (HTN-Preg). ET-1 activates endothelin
Publikováno v:
Journal of Cellular Physiology. 229:489-501
Normal pregnancy is associated with systemic vasodilation and decreased vascular contraction, partly due to increased release of endothelium-derived vasodilator substances. Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor acting via endo
Publikováno v:
British Journal of Pharmacology. 169:1335-1351
Background and Purpose Normal pregnancy is associated with decreased vascular resistance and increased release of vasodilators. Endothelin-1 (ET-1) causes vasoconstriction via endothelin receptor type A (ETAR), but could activate ETBR in the endothel