Effects of anti-TNF therapy and immunomodulators on anxiety and depressive symptoms in patients with inflammatory bowel disease: a 5-year analysis

Autor: Alexander R. Siebenhüner, Jean-Benoît Rossel, Philipp Schreiner, Matthias Butter, Thomas Greuter, Niklas Krupka, Sebastian B. U. Jordi, Luc Biedermann, Gerhard Rogler, Benjamin Misselwitz, Roland von Känel, Karim Abdelrahman, Gentiana Ademi, Patrick Aepli, Amman Thomas, Claudia Anderegg, Anca-Teodora Antonino, Eva Archanioti, Eviano Arrigoni, Nurullah Aslan, Diana Bakker de Jong, Bruno Balsiger, Mamadou-Pathé Barry, Polat Bastürk, Peter Bauerfeind, Andrea Becocci, José M. Bengoa, Janek Binek, Mirjam Blattmann, Stephan Boehm, Tujana Boldanova, Jan Borovicka, Christian P. Braegger, Stephan Brand, Francisco Bravo, Lukas Brügger, Simon Brunner, Patrick Bühr, Sabine Burk, Emanuel Burri, Sophie Buyse, Dahlia-Thao Cao, Ove Carstens, Dominique H. Criblez, Fabrizia D’Angelo, Philippe de Saussure, Lukas Degen, Joakim Delarive, Christopher Doerig, Barbara Dora, Susan Drerup, Carole Ducrey, Ali El-Wafa, Matthias Engelmann, Aude Erdmann-Voisin, Christian Felley, Markus Fliegner, Montserrat Fraga, Yannick Franc, Pascal Frei, Remus Frei, Michael Fried, Florian Froehlich, Raoul Ivano Furlano, Luca Garzoni, Martin Geyer, Marc Girardin, Delphine Golay, Ignaz Good, Ulrike Graf Bigler, Sébastien Godat, Beat Gysi, Johannes Haarer, Marcel Halama, Janine Haldemann, Pius Heer, Benjamin Heimgartner, Beat Helbling, Peter Hengstler, Denise Herzog, Cyrill Hess, Roxane Hessler, Klaas Heyland, Thomas Hinterleitner, Claudia Hirschi, Petr Hruz, Pascal Juillerat, Ioannis Kapoglou, Stephan Kayser, Céline Keller, Carolina Khalid-de Bakker, Christina Knellwolf, Christoph Knoblauch, Henrik Köhler, Rebekka Koller, Claudia Krieger, Patrizia Künzler, Rachel Kusche, Frank Serge Lehmann, Andrew Macpherson, Michel H. Maillard, Michael Manz, Maude Martinho, Rémy Meier, Christa Meyenberger, Pamela Meyer, Pierre Michetti, Bernhard Morell, Patrick Mosler, Eleni Moschouri, Christian Mottet, Christoph Müller, Beat Müllhaupt, Leilla Musso, Michaela Neagu, Cristina Nichita, Jan Niess, Andreas Nydegger, Nicole Obialo, Cassandra Oropesa, Ulrich Peter, Daniel Peternac, Laetitia Marie Petit, Valérie Pittet, Daniel Pohl, Marc Porzner, Claudia Preissler, Nadia Raschle, Ronald Rentsch, Sophie Restellini, Jean-Pierre Richterich, Sandra Riedmüller, Branislav Risti, Marc Alain Ritz, Nina Röhrich, René Roth, Vanessa Rueger, Markus Sagmeister, Gaby Saner, Riad Sarraj, Bernhard Sauter, Mikael Sawatzki, Michael Scharl, Sylvie Scharl, Martin Schelling, Susanne Schibli, Hugo Schlauri, Dominique Schluckebier, Daniela Schmid, Sybille Schmid, Jean-François Schnegg, Alain Schoepfer, Frank Seibold, Mariam Seirafi, Gian-Marco Semadeni, Arne Senning, Christiane Sokollik, Joachim Sommer, Johannes Spalinger, Holger Spangenberger, Philippe Stadler, Peter Staub, Dominic Staudenmann, Volker Stenz, Michael Steuerwald, Alex Straumann, Andreas Stulz, Michael Sulz, Michela Tempia-Caliera, Joël Thorens, Kaspar Truninger, Radu Tutuian, Patrick Urfer, Stephan Vavricka, Francesco Viani, Fabrizion Vinzens, Jürg Vögtlin, Roland Von Känel, Dominique Vouillamoz, Rachel Vulliamy, Marianne Vullièmoz, Paul Wiesel, Reiner Wiest, Stefanie Wöhrle, Bahtiyar Yilmaz, Samuel Zamora, Silvan Zander, Jonas Zeitz, Dorothee Zimmermann

Publikováno v: Therapeutic Advances in Gastroenterology, Vol 14 (2021)
Therapeutic Advances in Gastroenterology
Siebenhüner, Alexander R; Rossel, Jean-Benoît; Schreiner, Philipp; Butter, Matthias; Greuter, Thomas; Krupka, Niklas; Jordi, Sebastian B. U.; Biedermann, Luc; Rogler, Gerhard; Misselwitz, Benjamin; von Känel, Roland (2021). Effects of anti-TNF therapy and immunomodulators on anxiety and depressive symptoms in patients with inflammatory bowel disease: a 5-year analysis. Therapeutic advances in gastroenterology, 14, p. 17562848211033763. Sage 10.1177/17562848211033763

Background and aims: Anxiety and depression are prevalent in patients with inflammatory bowel diseases (IBD), especially during IBD flares. IBD therapies can profoundly affect the mood of patients with IBD. We aimed to determine the long-term impact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975339412907333a7cf29a55ea355b0c
https://doaj.org/article/43745c5791f945d5ac13a25da3873fd3

The armadillo protein p0071 controls KIF3 motor transport

Autor: René Keil, Paul Walther, Thomas Seufferlein, Susanne Bobrovich, Marc Porzner, Alexander Becher, Mechthild Hatzfeld, Tim Eiseler

Publikováno v: Journal of cell science. 130(19)

We here report a novel function of the armadillo protein p0071 (also known as PKP4) during transport mediated by the KIF3 transport complex. Secretion of chromogranin A and matrix metallopeptidase 9 from pancreatic neuroendocrine tumor cells or pancr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8f71cea976b0b380f6040b0a90532d
https://pubmed.ncbi.nlm.nih.gov/28808088

Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal tumours displaying either microsatellite stability (MSS) or instability (MSI)

Autor: Werner Hohenberger, Frank Boxberger, Thomas Kirchner, Andreas Jung, Eckhart G. Hahn, Stefan Ruckert, Petra Rümmele, Wolfgang Dietmaier, Marc Porzner, Axel Wein, Jens Grombach, Roland S. Croner, Wolfgang M. Brueckl

Publikováno v: Cancer Letters. 223:137-142

Methylation of promoter regions and frameshift mutations in microsatellites of the coding sequence (CDS) of genes are frequently associated with loss of expression in microsatellite instable (MSI) colorectal carcinoma. In a panel of 40 MSI and 24 mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fabd64b67cfc20b633bfbb0bbb96d66
https://doi.org/10.1016/j.canlet.2004.09.037

Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

Autor: Falk Hlubek, Ruth Knuechel, Thomas Kirchner, Leoni A. Kunz-Schughart, Simone Reu, Thomas Brabletz, Andreas Jung, Marc Porzner

Publikováno v: Proceedings of the National Academy of Sciences. 98:10356-10361

Invasion and dissemination of well-differentiated carcinomas are often associated with loss of epithelial differentiation and gain of mesenchyme-like capabilities of the tumor cells at the invasive front. However, when comparing central areas of prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ee126d758eee329e2c49e01f40c740
https://doi.org/10.1073/pnas.171610498

Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export

Autor: Julien Villeneuve, David Cruz-Garcia, Marko Jovic, Thomas Seufferlein, Tamas Balla, Marc Porzner, Margherita Scarpa, Vivek Malhotra, Maria Ortega-Bellido

Publikováno v: EMBO Journal.

The BAR (Bin/Amphiphysin/Rvs) domain proteins arfaptin1 and arfaptin2 are localized to the trans-Golgi network (TGN) and, by virtue of their ability to sense and/or generate membrane curvature, could play an important role in the biogenesis of transp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929f5ce16c95caf2f48c9c034035c9c2