Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Marc Pirrotta"'
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Akademický článek
Synthetic G-Quartets as Versatile Nanotools for the Luminescent Detection of G-Quadruplexes
Autor: Aurelien Laguerre, Marine Levillain, Loic Stefan, Romain Haudecoeur, Fares Katranji, Marc Pirrotta, David Monchaud
Publikováno v: CHIMIA, Vol 69, Iss 9 (2015)
Recent years have witnessed a tremendous increase in the biotechnological applications of nucleic acid-based nanotools. Beyond their biological relevance, nucleobases have indeed found new scopes of applications in bionanotechnology, which are expand
Externí odkaz: https://doaj.org/article/70b0afc7e85941b29cff05568f494e14
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3
Disclosing the actual efficiency of G-quadruplex-DNA–disrupting small molecules
Autor: Alexandra Joubert, Nicolas Desbois, Pauline Lejault, Jean-Baptiste Boulé, Anton Granzhan, Filip Wojciechowski, David Monchaud, Robert H. E. Hudson, Marc Pirrotta, Jeremie Mitteaux, Claude P. Gros
The quest for small molecules that avidly bind to G-quadruplex-DNA (G4-DNA, or G4), so called G4-ligands, has invigorated the G4 research field from its very inception. Massive efforts have been invested to i- screen or design G4-ligands, ii- evaluat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ae530f5ce376ec2f2de1798406f8df
https://doi.org/10.1101/2020.11.16.382176
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4
Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol
Autor: Sunny Y. Yang, David Monchaud, Isaline Renard, Apolline Roux, Pauline Lejault, Marc Pirrotta, Judy M. Y. Wong, Michael Grandmougin
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2019, 47 (11), pp.5502-5510. ⟨10.1093/nar/gkz215⟩
International audience; Guanine-rich DNA and RNA sequences can fold into higher-order structures known as G-quadruplexes (or G4-DNA and G4-RNA, respectively). The prevalence of the G4 landscapes in the human genome, transcriptome and ncRNAome (non-co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d5e7b480badd9ee69797db709386ef
https://hal.archives-ouvertes.fr/hal-02121536v2/document
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5
Visualization of RNA-Quadruplexes in Live Cells
Autor: Pascale Winckler, Judy M. Y. Wong, Fares Katranji, Jean-Marie Perrier-Cornet, Marc Pirrotta, Aurélien Laguerre, Gaëtan Chanteloup, David Monchaud, Kyle R. Hukezalie
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2015, 137 (26), pp.8521-8525. ⟨10.1021/jacs.5b03413⟩
Visualization of DNA and RNA quadruplex formation in human cells was demonstrated recently with different quadruplex-specific antibodies. Despite the significant interest in these immunodetection approaches, dynamic detection of quadruplex in live ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce164affa68a06d0277aac40fe9bff4
https://doi.org/10.1021/jacs.5b03413
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6
A Twice-As-Smart Synthetic G-Quartet: PyroTASQ Is Both a Smart Quadruplex Ligand and a Smart Fluorescent Probe
Autor: Aurélien Laguerre, Manuel Larrouy, Marc Pirrotta, David Genest, David Monchaud, Loic Stefan, Jana Novotna
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2014, 136 (35), pp.12406-12414. ⟨10.1021/ja506331x⟩
Recent and unambiguous evidences of the formation of DNA and RNA G-quadruplexes in cells has provided solid support for these structures to be considered as valuable targets in oncology. Beyond this, they have lent further credence to the anticancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e85b9c7818cdefb00a1a5bcdee3ef7
https://doi.org/10.1021/ja506331x
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7
Caffeine-Based Gold(I) N-Heterocyclic Carbenes as Possible Anticancer Agents: Synthesis and Biological Properties
Autor: Angela Casini, Pierre Le Gendre, Michel Picquet, Ewen Bodio, Elena Warmerdam, Marina H. de Jager, David Monchaud, Marc Pirrotta, Geny M. M. Groothuis, Loic Stefan, Philippe Richard, Benoît Bertrand
Publikováno v: Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2014, 53 (4), pp.2296-2303. ⟨10.1021/ic403011h⟩
Inorganic Chemistry, 53(4), 2296-2303. AMER CHEMICAL SOC
A new series of gold(I) N-heterocyclic carbene (NHC) complexes based on xanthine ligands have been synthesized and characterized by mass spectrometry, NMR, and X-ray diffraction. The compounds have been tested for their antiproliferative properties i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254c90e09ce2d2d7d20284bcd2535bf4
https://doi.org/10.1021/ic403011h
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8
DNA structure-specific sensitization of a metalloporphyrin leads to an efficient in vitro quadruplex detection molecular tool
Autor: Nicolas Desbois, Aurélien Laguerre, Claude P. Gros, David Monchaud, Marc Pirrotta, Julien Boudon, Pape Diaba Diabate
Publikováno v: New Journal of Chemistry
New Journal of Chemistry, Royal Society of Chemistry, 2016, 40 (7), pp.5683-5689. ⟨10.1039/c6nj01012a⟩
New Journal of Chemistry, Royal Society of Chemistry, 2016, 40 (7), pp.5683-5689. ⟨10.1039/C6NJ01012A⟩
New Journal of Chemistry, Royal Society of Chemistry, 2016, 40 (7), pp.5683-5689. 〈http://pubs.rsc.org/en/content/articlelanding/2016/nj/c6nj01012a#!divAbstract〉. 〈10.1039/c6nj01012a〉
International audience; The search for convenient molecular probes for detecting DNA and RNA quadruplexes in vitro is marked by a rapid pace of progress, spurred on by the multiple roles these higher-order nucleic acid structures play in many genetic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f18c0c80af172b555fe1ff8f0ba549
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01427995
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9
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties
Autor: Nicolas Spinelli, Muriel Jourdan, Thibaut Constantin, Sylvain Penasse, Marc Pirrotta, Aurélien Laguerre, Jérôme Dejeu, David Monchaud, Eric Defrancq, Béatrice Gennaro, Theodore Flack
Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2016, 22 (5), pp.1760-1767. ⟨10.1002/chem.201504572⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2016, 22 (5), pp.1760-1767. 〈http://onlinelibrary.wiley.com/doi/10.1002/chem.201504572/full〉. 〈10.1002/chem.201504572〉
International audience; A water-soluble template-assembled synthetic G-quartet (TASQ) based on the use of a macrocyclodecapeptide scaffold was designed to display stable intramolecular folds alone in solution. The preformation of the guanine quartet,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419fb3846b00e92a4142631145b62e60
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01400347
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10
Synthetic G-Quartets as Versatile Nanotools for the Luminescent Detection of G-Quadruplexes
Autor: Fares Katranji, Marc Pirrotta, Loic Stefan, David Monchaud, Marine Levillain, Aurélien Laguerre, Romain Haudecoeur
Publikováno v: CHIMIA International Journal for Chemistry
CHIMIA International Journal for Chemistry, 2015, 69 (9), pp.530-536. ⟨10.2533/chimia.2015.530⟩
CHIMIA, Vol 69, Iss 9 (2015)
Recent years have witnessed a tremendous increase in the biotechnological applications of nucleic acid-based nanotools. Beyond their biological relevance, nucleobases have indeed found new scopes of applications in bionanotechnology, which are expand
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00f7ea9dc95588821f0985311ca8a79
https://hal.archives-ouvertes.fr/hal-02125788
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