Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Marc Peters"'
Autor:
Judy Chen, Jane C. Deng, Rachel L. Zemans, Karim Bahmed, Beata Kosmider, Min Zhang, Marc Peters-Golden, Daniel R. Goldstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Ageing has been associated with impaired function of alveolar macrophages and increased susceptibility, mortality and complications as a result of viral infection. Here, the authors show that prostaglandin E2 is one of the factors responsible for imp
Externí odkaz:
https://doaj.org/article/3c42d5d95c814302adbeaa6e8a8f666d
Autor:
Loka R. Penke, Jennifer M. Speth, Steven K. Huang, Sean M. Fortier, Jared Baas, Marc Peters-Golden
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
There is a paucity of information about potential molecular brakes on the activation of fibroblasts that drive tissue fibrosis. The transcription factor Krüppel-like factor 4 (KLF4) is best known as a determinant of cell stemness and a tumor suppres
Externí odkaz:
https://doaj.org/article/23beb506a1994293913bc27aaa06d517
Autor:
Nils Helge Schebb, Hartmut Kühn, Astrid S. Kahnt, Katharina M. Rund, Valerie B. O’Donnell, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Karsten H. Weylandt, Nadine Rohwer, Robert C. Murphy, Gerd Geisslinger, Garret A. FitzGerald, Julien Hanson, Claes Dahlgren, Mohamad Wessam Alnouri, Stefan Offermanns, Dieter Steinhilber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 1
Externí odkaz:
https://doaj.org/article/4d550b6401b044cfacb01d9180ee3c13
Autor:
Sean M. Fortier, Loka R. Penke, Dana King, Tho X. Pham, Giovanni Ligresti, Marc Peters-Golden
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
Myofibroblasts are the major cellular source of collagen, and their accumulation — via differentiation from fibroblasts and resistance to apoptosis — is a hallmark of tissue fibrosis. Clearance of myofibroblasts by dedifferentiation and restorati
Externí odkaz:
https://doaj.org/article/89b072c87a6d4848a2be99408bbc503f
Autor:
Thalia Bekelaar, Gervais Nougon, Marc Peters, Frederic De Roeck, Steven Haine, Dirk Ysebaert, Maarten Spinhoven, Philippe G. Jorens, Rudi De Paep, Frederik Lahaye
Publikováno v:
Case Reports in Cardiology, Vol 2021 (2021)
Cardiogenic shock during a pheochromocytoma crisis is a life-threatening disorder. This case report illustrates a 49-year-old male with profound cardiogenic shock, extreme hemodynamic instability (systolic blood pressure ranging from 45 up to 290 mmH
Externí odkaz:
https://doaj.org/article/2a5090587c4e4bea88f16b96923b39c1
Autor:
Norbert F. Voelkel, Marc Peters-Golden
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
It has been generally accepted that severe forms of pulmonary arterial hypertension are associated with inflammation. Plasma levels in patients with severe pulmonary arterial hypertension show elevated levels of interleukins and mediators of inflamma
Externí odkaz:
https://doaj.org/article/3b512bc9ac974ca6a8430598a03982ae
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Bitter taste evokes aversive behaviour in animals, but little is known about the central nervous system mechanisms that convey this taste modality. Hückesfeld et al. identify a set of second order neurons in Drosophilathat contain hugin neuropeptide
Externí odkaz:
https://doaj.org/article/62147908fd2c4c0d9033bc999dbe280c
Publikováno v:
Cells, Vol 9, Iss 7, p 1589 (2020)
Extracellular vesicles (EVs) contain a diverse array of molecular cargoes that alter cellular phenotype and function following internalization by recipient cells. In the lung, alveolar macrophages (AMs) secrete EVs containing suppressor of cytokine s
Externí odkaz:
https://doaj.org/article/f2c94451190e4852b50e892933b04942
Autor:
Tetsuji Aoyagi, Michael W Newstead, Xianying Zeng, Yuta Nanjo, Marc Peters-Golden, Mitsuo Kaku, Theodore J Standiford
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006737 (2017)
Pseudomonas aeruginosa is a Gram-negative pathogen that can lead to severe infection associated with lung injury and high mortality. The interleukin (IL)-36 cytokines (IL-36α, IL-36β and IL-36γ) are newly described IL-1 like family cytokines that
Externí odkaz:
https://doaj.org/article/4acc2c4092074f12a663f1d3404037cc
Autor:
Carla da S. Pinheiro, Ana Paula T. Monteiro, Fabiano F. Dutra, Marcelo T. Bozza, Marc Peters-Golden, Claudia F. Benjamim, Claudio Canetti
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, i
Externí odkaz:
https://doaj.org/article/97d92a8d28ed4d9486dd9c3e955821f5