Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marc Payard"'
Autor:
Genevieve Baziard-Mouysset, Henri Vial, Maynadier Marjorie, Salome El Hage, Michèle Ane, Marc Payard, Jean-Luc Stigliani
Publikováno v:
European Journal of Medicinal Chemistry. 44:4778-4782
In this paper we describe the design and synthesis of 18 derivatives of the antimicrobial atovaquone which were substituted at the 3-hydroxy group by ester and ether functions. The compounds were evaluated in vitro for their activity against the grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e78f5ad7a3da6fa6cca13d569cd46a
https://doi.org/10.1016/j.ejmech.2009.07.021
https://doi.org/10.1016/j.ejmech.2009.07.021
Autor:
Bruno Pfeiffer, Marc Payard, Stephan Schann, Hugues Greney, Pascal Bousquet, Jean A. Boutin, Christian Jarry, Véronique Bruban, Elizabeth Scalbert, Monique Dontenwill, Paul M. Vanhoutte, Josiane Feldman, Pierre Renard
Publikováno v:
British Journal of Pharmacology. 133:261-266
The hypotensive effect of imidazoline-like drugs, such as clonidine, was first attributed to the exclusive stimulation of central α2-adrenoceptors (α2ARs). However, a body of evidence suggests that non-adrenergic mechanisms may also account for thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b243a90c28fda20190fdf869f52e9ba0
https://doi.org/10.1038/sj.bjp.0704080
https://doi.org/10.1038/sj.bjp.0704080
Autor:
Pierre Renard, S Younes, Bruno Pfeiffer, Daniel-Henri Caignard, Genevieve Baziard-Mouysset, Youssef Labssita, Marie-Claire Rettori, Marc Payard
Publikováno v:
European Journal of Medicinal Chemistry. 35:107-121
Continuing our previous work that established that some chromones substitued by an aryl alkyl piperazino alkyl side chain are potent and selective sigma ligands and could be interesting in the treatment of psychosis, we synthesized 60 new compounds,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef61f2a4d9daaf0759177280f278b774
https://doi.org/10.1016/s0223-5234(00)00113-6
https://doi.org/10.1016/s0223-5234(00)00113-6
Autor:
Guy Mousset, Marc Payard, Pierre Palvadeau, Genevieve Baziard-Mouysset, Kamal Boubekeur, Pascale Besse, Henri Veschambre
Publikováno v:
Tetrahedron: Asymmetry. 10:4745-4754
From the microbiological reductions of 2-acetyl or 2-benzoylchromen-4-one both enantiomers of the corresponding alcohols were obtained with high enantiomeric excess. The absolute configurations were determined directly by an X-ray structural determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6826d21c2661fadeddc1d229096b84f7
https://doi.org/10.1016/s0957-4166(99)00558-3
https://doi.org/10.1016/s0957-4166(99)00558-3
Autor:
R. Caujolle, J. P. Seguela, C. Tournaire‐Arellano, M. D. Linas, J. L. Stigliani, C. Recoche, Marc Payard
Publikováno v:
European Journal of Medicinal Chemistry. 32:1001-1007
Summary Ethers of 1-(2,4-dichlorophenyl)-2-(1- H -imidazolyl)ethanol bearing ramified and/or unsaturated chains have been synthesized in order to specify the role of lipophilicity or steric contributions on antifungal activity against yeast for micon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d04456e14014d93e3ab61e85c1ab884a
https://doi.org/10.1016/s0223-5234(97)89644-4
https://doi.org/10.1016/s0223-5234(97)89644-4
Autor:
Bruno Pfeiffer, Marie-Claire Rettori, Salouma Younes, Genevieve Baziard-Mouysset, Beatrice Guardiola-Lemaitre, Pierre Renard, Marc Payard, Daniel-Henri Caignard, Youssef Labssita
Publikováno v:
European Journal of Medicinal Chemistry. 33:339-347
Starting from a random screening showing that 2-[(4-benzylpiperazinyl)methyl] chromone was a selective and potent sigma ligand, a series of analogues were synthesized. Introduction of a substituent on the chromone moiety, replacement of methy-lenes b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec27962b6ced0606e35d05a34b9db4e
https://doi.org/10.1016/s0223-5234(98)80001-9
https://doi.org/10.1016/s0223-5234(98)80001-9
Publikováno v:
Journal of Natural Products. 61:480-484
A series of 18 aporphinoids have been tested in vitro against human poliovirus. The aporphines (+)-glaucine fumarate (1), (+)-N-methyllaurotetanine (4), (+)-isoboldine (7), and (-)-nuciferine, HCl (10) were found to be active with selectivity indices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c2545e7f06190cd4995c36cb3a0cc2
https://doi.org/10.1021/np970382v
https://doi.org/10.1021/np970382v
Autor:
C. Bories, Philippe Gayral, M. H. Bessieres, C Tournaire, Marc Payard, G. Commenges, R. Caujolle, Philippe M. Loiseau
Publikováno v:
European Journal of Medicinal Chemistry. 31:507-511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6641184924dc23d6d593dd429f586d9
https://doi.org/10.1016/0223-5234(96)85172-5
https://doi.org/10.1016/0223-5234(96)85172-5
Publikováno v:
European Journal of Medicinal Chemistry. 30:955-962
Summary Aromatic ethers related to antifungal azole miconazole were synthesized and tested against various strains of Candida . We found that activity is related to the nature of the aromatic ring and the position of substituents on this ring. Activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09fa6dee717e1ef9c17adcf6a2bf4de0
https://doi.org/10.1016/0223-5234(96)88315-2
https://doi.org/10.1016/0223-5234(96)88315-2
Autor:
Philippe Gayral, J. P. Seguela, Christian Bories, H Amarouch, Linas, R Caujolle, Marc Payard, Philippe M. Loiseau
Publikováno v:
European Journal of Medicinal Chemistry. 30:801-807
Twenty-three arylthioureines bearing β-alanine or γ-aminobutyric alkyl ester chains were synthesized for in vitro screening toward 44 strains of fungi and 2 genera of nematodes. The nitro derivatives were the most potent compounds against Aspergill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::191e968f0e7f16faa73c7e0b24718c63
https://doi.org/10.1016/0223-5234(96)88299-7
https://doi.org/10.1016/0223-5234(96)88299-7