Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marc P. Lussier"'
Autor:
Valérie C. Cabana, Marc P. Lussier
Publikováno v:
Cells, Vol 11, Iss 3, p 380 (2022)
The ubiquitin–proteasome system is of fundamental importance in all fields of biology due to its impact on proteostasis and in regulating cellular processes. Ubiquitination, a type of protein post-translational modification, involves complex enzyma
Externí odkaz:
https://doaj.org/article/97ac01d6e3264293bd10cecafbb8f712
Autor:
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Kim Ghilarducci, Saïd Kourrich, Laurent Cappadocia, Marc P. Lussier
Publikováno v:
Cells, Vol 10, Iss 11, p 3063 (2021)
Developmental and epileptic encephalopathies (DEE) are rare and serious neurological disorders characterized by severe epilepsy with refractory seizures and a significant developmental delay. Recently, DEE73 was linked to genetic alterations of the R
Externí odkaz:
https://doaj.org/article/19041a9cefa4484d8aa32a40fe48c868
Autor:
Xinglong Gu, Xia Mao, Marc P. Lussier, Mary Anne Hutchison, Liang Zhou, F. Kent Hamra, Katherine W. Roche, Wei Lu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
The molecular mechanism controlling the trafficking and function of AMPARs at synapses are not fully understood. Here the authors show that GSG1L, a membrane protein, negatively regulates AMPAR-mediated synaptic transmission and represents a new clas
Externí odkaz:
https://doaj.org/article/da577629600d4e19af92086f063fbc57
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7847
Rab7 is a GTPase that controls late endosome and lysosome trafficking. Recent studies have demonstrated that Rab7 is ubiquitinated, a post-translational modification mediated by an enzymatic cascade. To date, only one ubiquitin E3 ligase and one deub
Autor:
Véronik Lachance, Sara-Maude Bélanger, Célia Hay, Victoria Le Corvec, Vina Banouvong, Mathieu Lapalme, Khadija Tarmoun, Guillaume Beaucaire, Marc P. Lussier, Saïd Kourrich
Publikováno v:
International Journal of Molecular Sciences. 24:1971
For the past several years, fundamental research on Sigma-1R (S1R) protein has unveiled its necessity for maintaining proper cellular homeostasis through modulation of calcium and lipid exchange between the endoplasmic reticulum (ER) and mitochondria
Autor:
Valérie C, Cabana, Marc P, Lussier
Publikováno v:
Cells. 11(3)
The ubiquitin-proteasome system is of fundamental importance in all fields of biology due to its impact on proteostasis and in regulating cellular processes. Ubiquitination, a type of protein post-translational modification, involves complex enzymati
Autor:
Audrey M Sénécal, Antoine Y Bouchard, Laurent Cappadocia, Kim Ghilarducci, Valérie C. Cabana, Marc P. Lussier, Saïd Kourrich
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3063, p 3063 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3063, p 3063 (2021)
Developmental and epileptic encephalopathies (DEE) are rare and serious neurological disorders characterized by severe epilepsy with refractory seizures and a significant developmental delay. Recently, DEE73 was linked to genetic alterations of the R
Autor:
Valérie C. Cabana, Steve Bourgault, Kim Ghilarducci, Marc P. Lussier, Kahina Chabi, Laurent Cappadocia, Camille Desroches
Publikováno v:
The FEBS journalReferences. 288(16)
Protein ubiquitination has been historically associated with protein degradation, but recent studies have demonstrated other cellular functions associated with substrate ubiquitination. Among the RING-type ubiquitin E3 ligase enzymes present in the h
Publikováno v:
Neuroscience. 442
Optimal synaptic activity is essential for cognitive function, including memory and learning. Evidence indicates that cognitive decline in elderly individuals is associated with altered synaptic function. However, the impact of aging on the expressio
Publikováno v:
The Biochemical journal. 474(13)
Secretin is a peptide hormone that exerts pleiotropic physiological functions by specifically binding to its cognate membrane-bound receptor. The membrane catalysis model of peptide–receptor interactions states that soluble peptidic ligands initial