Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marc Oliva Bernal"'
Autor:
Julio Jose Lambea Sorrosal, Gema Bruixola, Javier Martinez-Trufero, Beatriz Cirauqui, Almudena García Castaño, Javier Caballero Daroqui, Jordi Rubió-Casadevall, Ricard Mesia, Pedro Perez, Alberto Carral, Vanesa Gutierrez Calderon, Edel del Barco, Joaquina Martínez-Galán, Marc Oliva Bernal, Laura Basterretxea, Virginia Arrazubi, Lara Iglesias, Ruth Alvarez, Ana Medina, Neus Basté Rotllán, Neck Cancer Treatment
Publikováno v:
Journal of Clinical Oncology. 39:TPS6086-TPS6086
TPS6086 Background: Nivolumab is the standard of care for patients (pts) with R/M HNSCC in the platinum-refractory setting. Up to 20% of R/M HNSCC pts are ineligible for cisplatin-based CT due to poor performance status and/or comorbidities. ERBITAX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2c9753b15279c7a6fd5a67649355aa3
https://doi.org/10.1200/jco.2021.39.15_suppl.tps6086
https://doi.org/10.1200/jco.2021.39.15_suppl.tps6086
Autor:
Marc Oliva Bernal, Jesús Brenes Castro, Alicia Lozano, Marta Fulla, Sandra Llop Serna, Maria Teresa Plana, Mireia Melero, Miren Taberna, Victoria Gomez Garcia, Ricard Mesia, Macarena Honorato, Montse Goma, Maite Antonio Rebollo, Oriol Bermejo, Clara Ejarque Martinez, M. Esther Vilajosana Altamis, Isabel Linares
Publikováno v:
Journal of Clinical Oncology. 39:6057-6057
6057 Background: Up to 24% of patients (pts) newly-diagnosed with LA-HNSCC are 70 years old (yo). NCCN guidelines recommend a geriatric assessment to guide treatment decisions in this pts population. Comprehensive geriatric assessment (CGA) of older
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738a335f0f2528c346a35be601886e07
https://doi.org/10.1200/jco.2021.39.15_suppl.6057
https://doi.org/10.1200/jco.2021.39.15_suppl.6057
Autor:
Rachel Chen, Abdulazeez Salawu, Marc Oliva Bernal, Daniel Vilarim Araujo, Alberto Hernando-Calvo, Lillian L. Siu, Zhihui (Amy) Liu
Publikováno v:
Journal of Clinical Oncology. 39:2648-2648
2648 Background: Despite an exponential increase in the number of potential targets in the immuno-oncology (IO) field, lack of risk models to predict toxicities remains a challenge in early drug development. We proposed a risk stratification strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d262a0c0665f0f441de0fe94c9c098b6
https://doi.org/10.1200/jco.2021.39.15_suppl.2648
https://doi.org/10.1200/jco.2021.39.15_suppl.2648
Autor:
Daniel Vilarim Araujo, Zhihui (Amy) Liu, Lillian L. Siu, Marc Oliva Bernal, Rachel Chen, Alberto Hernando-Calvo, Abdulazeez Salawu
Publikováno v:
Journal of Clinical Oncology. 39:2653-2653
2653 Background: Pharmacodynamic biomarkers (PD) are considered fundamental for go/no-go decisions in phase 1 trials. Despite an increase in the availability of blood-based biomarker assays, the requirement of invasive non-diagnostic research tumor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017cf6fd2efecc20fe41bb4114745584
https://doi.org/10.1200/jco.2021.39.15_suppl.2653
https://doi.org/10.1200/jco.2021.39.15_suppl.2653
Autor:
Francisca Morey Cortes, Pau Guillen Sentis, Alicia Lozano, Maria Teresa Plana, Marc Oliva Bernal, Jesús Brenes Castro, Beatriz Quirós, Maria Labori Trias, Miren Taberna, Isabel Linares, Sara Tous, Antonio Mari Roig, Ricard Mesia, M. Esther Vilajosana Altamis, Jordi Tornero Salto, Carmen Castillo Manzano, Victoria Gomez Garcia, Montse Goma, Laia Alemany, Oriol Bermejo
Publikováno v:
Journal of Clinical Oncology. 39:6061-6061
6061 Background: Treatment (ttm) of cancer patients (pts) was compromised during the first wave of COVID19 pandemic due to collapse of healthcare systems. Standard of care (SOC) for LA-HNSCC pts had to be adapted as operating rooms were temporarily u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed753fe17fac3e933251bcd030242b48
https://doi.org/10.1200/jco.2021.39.15_suppl.6061
https://doi.org/10.1200/jco.2021.39.15_suppl.6061
Autor:
Marc Oliva Bernal, Lillian L. Siu, Aaron R. Hansen, Sarah Jennings, Anneli Eliason, Rachel Taylor, Wei Xu, Scott V. Bratman, Bayardo Perez-Ordonez, Douglas B. Chepeha, Bryan Coburn, Ilan Weinreb, John Waldron, Andrew Hope, Ali Hosni, Geoffrey Alan Watson, Kyla Cochrane, Emma Allen-Vercoe, Alya Heirali, Anna Spreafico
Publikováno v:
Journal of Clinical Oncology. 39:6059-6059
6059 Background: Therapeutic manipulation of the gut microbiome in cancer patients (pts) is an area of active investigation. MET4 (NuBiyota) is an oral alternative to fecal transplant consisting of a mixture of human gut bacteria associated with immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::956cb3861d303745e5e4396a606acc61
https://doi.org/10.1200/jco.2021.39.15_suppl.6059
https://doi.org/10.1200/jco.2021.39.15_suppl.6059
Autor:
Aaron R. Hansen, Trevor J. Pugh, Ben X Wang, John R. de Almeida, Ilan Weinreb, Isan Chen, Daniel Vilarim Araujo, Scott V. Bratman, Bayardo Perez-Ordonez, Marc Oliva Bernal, Hirak Der-Torossian, Anna Spreafico, Douglas B. Chepeha, Tina Shek, Andrew Hope, Amy Prawira, Jonathan C. Irish, Lillian L. Siu, David P. Goldstein, Pamela S. Ohashi
Publikováno v:
Journal of Clinical Oncology. 38:6569-6569
6569 Background: Sitravatinib (receptor TKI against TYRO3, AXL, MERTK and VEGF family of receptors) is predicted to increase M1-type tumor-associated macrophages (TAMs) and decrease MDSCs in the tumor microenvironment. SNOW is a window-of-opportunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede540deee1d71f04bd95214e7ae4172
https://doi.org/10.1200/jco.2020.38.15_suppl.6569
https://doi.org/10.1200/jco.2020.38.15_suppl.6569
Autor:
Lee-Anne Stayner, Tira Jing Ying Tan, Lillian L. Siu, Wei Xu, Daniel Vilarim Araujo, Pierre H. H. Schneeberger, Shawn Langer, Alya Heirali, Anna Spreafico, David Hogg, Nissim Mashiach, Bryan Coburn, Aaron R. Hansen, Marc Oliva Bernal, Thiago Pimentel Muniz, Kyla Cochrane, Ben X Wang, Bo Chen, Kathy Xia
Publikováno v:
Journal of Clinical Oncology. 38:3098-3098
3098 Background: Therapeutic augmentation of the intestinal microbiome to improve immunotherapy outcomes is an active area of investigation. Microbial Ecosystem Therapeutics (METs) are consortia of human-derived bacteria designed to be reproducible,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44700e9872761750fb3d5f4b95c5df6
https://doi.org/10.1200/jco.2020.38.15_suppl.3098
https://doi.org/10.1200/jco.2020.38.15_suppl.3098
Autor:
Marc Oliva Bernal, Douglas Chepeha, Amy Prawira, Douglass Vines, Anna Spreafico, Scott Bratman, John De Almeida, Aaron Hansen, David Goldstein, Ralph Gilbert, Patrick Gullane, Dale H. Brown, Ilan Weinreb, Bayardo Perez-Ordoñez, Pamela S. Ohashi, Tracy McGaha, Ben X. Wang, Jonathan Irish, Isan Chen, Lillian L. Siu
Publikováno v:
Cancer Research. 79:CT124-CT124
Background: Squamous cell carcinoma of the oral cavity (SCCOC) often presents at early stages but its prognosis remains guarded, with a 5-year survival rate of 60% despite curative-intent therapies. Preoperative window-of-opportunity (WOO) studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc76a50bd1a218111604d003ca7cdeb
https://doi.org/10.1158/1538-7445.am2019-ct124
https://doi.org/10.1158/1538-7445.am2019-ct124
Autor:
Ralph W. Gilbert, Marc Oliva Bernal, Bayardo Perez-Ordonez, Victor Rey, Ali Hosni, John Waldron, Bryan Coburn, Lillian L. Siu, Jolie Ringash, Scott V. Bratman, Andrew Bayley, Rachel Taylor, Ilan Weinreb, Pierre H. H. Schneeberger, Anna Spreafico, Kirsty Taylor, David S. Guttman, Andrew Hope, Aaron R. Hansen, Wei Xu
Publikováno v:
Journal of Clinical Oncology. 37:6045-6045
6045 Background: The ROMA LA-OPSCC ( NCT03759730) study prospectively evaluated the oral and gut microbiota in a single-centre cohort of LA-OPSCC patients (pts) receiving chemoradiotherapy (CRT). Methods: LA-OPSCC pts treated with definitive CRT (IMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d190aa34e19749b62747f8613b482b83
https://doi.org/10.1200/jco.2019.37.15_suppl.6045
https://doi.org/10.1200/jco.2019.37.15_suppl.6045