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pro vyhledávání: '"Marc Nugent"'
Publikováno v:
Neuropharmacology. 138:257-266
Transient receptor potential (TRP) vallinoid 1 (TRPV1) and ankyrin 1 (TRPA1) are two transducing channels expressed on peripheral sensory nerves involved in pain sensation. Upregulation of their expression, stimulated by inflammatory cytokines and gr
Autor:
Jiafu Wang, J. Oliver Dolly, Marc Nugent, Tomas H. Zurawski, Joan A. Geoghegan, Gary W. Lawrence
Publikováno v:
Bioconjugate chemistry. 28(6)
Numerous naturally occurring toxins can perturb biological systems when they invade susceptible cells. Coupling of pertinent targeting ligands to the active domains of such proteins provides a strategy for directing these to particular cellular popul
Publikováno v:
Scientific Reports
Botulinum neurotoxins (BoNTs) are the most toxic proteins known, due to inhibiting the neuronal release of acetylcholine and causing flaccid paralysis. Most BoNT serotypes target neurons by binding to synaptic vesicle proteins and gangliosides via a
Publikováno v:
Toxicon. 159:S5
Publikováno v:
15th Atmospheric Flight Mechanics Conference.