Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marc Nahmani"'
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Synaptic spinules are thin, finger-like projections from one neuron that become embedded within the presynaptic or postsynaptic compartments of another neuron. While spinules are conserved features of synapses across the animal kingdom, their specifi
Externí odkaz:
https://doaj.org/article/26ffbb958076470189d27ed40b533cf3
Synaptic spinules are thin, finger-like projections from one neuron that become fully embedded within the presynaptic or postsynaptic compartments of another neuron. While spinules are a conserved feature of synapses across the animal kingdom, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59842d387c6fa3fab0dd413ab2a3bded
https://doi.org/10.1101/2022.06.11.495762
https://doi.org/10.1101/2022.06.11.495762
Autor:
Marc Nahmani, Jaclyn McCoy
Publikováno v:
Journal of visualized experiments : JoVE. (175)
Recent advances in scanning electron microscope technologies now permit the rapid three-dimensional (3D) analysis of ultrathin subcellular processes. Here, a methodological pipeline is presented to identify, visualize, and analyze thin neuronal proce
Publikováno v:
Proceedings of the National Academy of Sciences. 114:3832-3836
Superresolution microscopy has fundamentally altered our ability to resolve subcellular proteins, but improving on these techniques to study dense structures composed of single-molecule-sized elements has been a challenge. One possible approach to en
Publikováno v:
eNeuro
Despite decades of discussion in the neuroanatomical literature, the role of the synaptic ‘spinule’ in synaptic development and function remains elusive. Canonically, spinules are finger-like projections that emerge from postsynaptic spines and c
Publikováno v:
Neuron. 68:750-762
SummaryIn visual cortex monocular deprivation (MD) during a critical period (CP) reduces the ability of the deprived eye to activate cortex, but the underlying cellular plasticity mechanisms are incompletely understood. Here we show that MD reduces t
Autor:
Robert Haslinger, Alev Erisir, Marc Nahmani, Jeffrey P. Gavornik, Arnold J. Heynen, Mark F. Bear, Jason E. Coleman
Publikováno v:
Journal of Neuroscience. 30:9670-9682
Monocular lid closure (MC) causes a profound shift in the ocular dominance (OD) of neurons in primary visual cortex (V1). Anatomical studies in both cat and mouse V1 suggest that large-scale structural rearrangements of eye-specific thalamocortical (
Publikováno v:
Neuroscience. 163:920-932
Activity-dependent modulation of N-methyl-d-aspartate (NMDA) receptors containing selective NR2 subunits has been implicated in plastic processes in developing and adult sensory cortex. Aiming to reveal differential sensitivity of NR2 subunits to sus
Publikováno v:
Neuron. 58(3):387-400
SummaryFast-spiking cells (FS cells) are a prominent subtype of neocortical GABAergic interneurons with important functional roles. Multiple FS cell properties are coordinated for rapid response. Here, we describe an FS cell feature that serves to ga
Synaptic scaling is a form of homeostatic plasticity that stabilizes neuronal firing in response to changes in synapse number and strength. Scaling up in response to action-potential blockade is accomplished through increased synaptic accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12b2fbcb8028f58241b0f4c75ea78ba
https://europepmc.org/articles/PMC4500210/
https://europepmc.org/articles/PMC4500210/