Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Marc Michael Zaruba"'
Autor:
Lukas Lanser, Gerhard Poelzl, Moritz Messner, Maria Ungericht, Marc‐Michael Zaruba, Jakob Hirsch, Stefan Hechenberger, Stefan Obersteiner, Bernhard Koller, Hanno Ulmer, Guenter Weiss
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Iron deficiency (ID) is a frequent comorbidity in patients with acute (AHF) and chronic heart failure (CHF) associated with morbidity and death. We aimed to better characterize iron homeostasis in patients with heart failure applying diffe
Externí odkaz:
https://doaj.org/article/1564043fad2b4eaa8df9d8ea89805dec
Autor:
Marc-Michael Zaruba, Simon Staggl, Santhosh Kumar Ghadge, Thomas Maurer, Jasmina Gavranovic-Novakovic, Vivek Jeyakumar, Patric Schönherr, Andreas Wimmer, Gerhard Pölzl, Axel Bauer, Moritz Messner
Publikováno v:
Cells, Vol 13, Iss 13, p 1074 (2024)
Activation of the CXCL12/CXCR4/ACKR3 axis is known to aid myocardial repair through ischemia-triggered hypoxia-inducible factor-1α (HIF-1α). To enhance the upregulation of HIF-1α, we administered roxadustat, a novel prolyl hydroxylase inhibitor (P
Externí odkaz:
https://doaj.org/article/fa27c5de99a142788d29eb4235130afd
Autor:
Florian Kocher, Alex Kaser, Felix Escher, Jacob Doerler, Marc‐Michael Zaruba, Moritz Messner, Christine Mussner‐Seeber, Agnes Mayr, Hanno Ulmer, Stephanie Schneiderbauer‐Porod, Christian Ebner, Gerhard Poelzl
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3919-3928 (2020)
Abstract Aims Amyloid cardiomyopathy is an underappreciated cause of morbidity and mortality. Recent evidence suggests that ATTR wild‐type cardiomyopathy (ATTRwt‐CM) is probably much more common than widely appreciated. So far, no data are availa
Externí odkaz:
https://doaj.org/article/de0a3c32300141b08ae3693e1dabcee9
Autor:
Moritz Messner, Santhosh Kumar Ghadge, Thomas Maurer, Michael Graber, Simon Staggl, Sarah Christine Maier, Gerhard Pölzl, Marc-Michael Zaruba
Publikováno v:
Cells, Vol 9, Iss 9, p 1981 (2020)
Lamins are important filaments forming the inner nuclear membrane. Lamin A is processed by zinc metalloproteinase (ZMPSTE24). Failure to cleave a truncated form of prelamin A—also called progerin—causes Hutchinson–Gilford progeria syndrome a we
Externí odkaz:
https://doaj.org/article/1ab907d1b5cc4071aa35d2239a78c3aa
Autor:
Moritz Messner, Santhosh Kumar Ghadge, Valentina Goetsch, Andreas Wimmer, Jakob Dörler, Gerhard Pölzl, Marc-Michael Zaruba
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196739 (2018)
Mutations in the LMNA gene are a common cause (6-8%) of dilated cardiomyopathy (DCM) leading to heart failure, a growing health care problem worldwide. The premature aging disease Hutchinson-Gilford syndrome (HGPS) is also caused by defined mutations
Externí odkaz:
https://doaj.org/article/954ee0c380b24b74b1917793913c564d
Autor:
Stefan Aschauer, Nicolas Verheyen, Roland Schwarz, Diana Bonderman, Julia Mascherbauer, Thomas Weber, Renate Kain, Andreas A. Kammerlander, Agnes Mayr, Marc Michael Zaruba, Christian Ebner, Peter P. Rainer, Klemens Ablasser, Christian Nitsche, Matthias Schneider, Roza Badr Eslam, Gerhard Pölzl, Martin Hülsmann, Alexander Kroiss, Susanne Reiter-Malmqvist, Michaela Auer-Grumbach, Jakob Dörler, Matthias Koschutnik, Hermine Agis, Christina Binder, Franz Duca, Marcus Hacker
Publikováno v:
Wiener Klinische Wochenschrift
SummaryThe prevalence and significance of cardiac amyloidosis have been considerably underestimated in the past; however, the number of patients diagnosed with cardiac amyloidosis has increased significantly recently due to growing awareness of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d32d2c886e9ce2eafe2b252fcf4eaf8
http://europepmc.org/articles/PMC7732807
http://europepmc.org/articles/PMC7732807
Autor:
Maria Ungericht, Julia Wanschitz, Alexander S. Kroiss, Christoph Röcken, Thomas Schuetz, Moritz Messner, Marc-Michael Zaruba, Wolfgang N. Loescher, Gerhard Poelzl
Publikováno v:
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
We identified two patients with transthyretin (ATTR) amyloid myopathy (one ATTR variant amyloidosis, ATTRv; one wild-type ATTR amyloidosis, ATTRwt). Myopathy was the initial manifestation in ATTRwt, whereas it followed neuropathy and cardiomyopathy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1954c96a8d241cc85dd4022e8b74bc45
https://pubmed.ncbi.nlm.nih.gov/35581484
https://pubmed.ncbi.nlm.nih.gov/35581484
Publikováno v:
European Heart Journal - Case Reports. 6
Background Eosinophilic myocarditis (EM) is a rare disease with different clinical pictures and disease courses. Little literature is available on the various courses of the disease. Case summary A previously healthy 44-year-old male patient presente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0eae6983da087fab22cdbc651161dce
https://doi.org/10.1093/ehjcr/ytac055
https://doi.org/10.1093/ehjcr/ytac055
Autor:
Jutta Bergler-Klein, Peter P. Rainer, Markus Wallner, Marc-Michael Zaruba, Jakob Dörler, Armin Böhmer, Tamara Buchacher, Maria Frey, Christopher Adlbrecht, Rupert Bartsch, Mariann Gyöngyösi, Ursula-Maria Fürst
Publikováno v:
Wiener klinische Wochenschrift. 134(17-18)
SummarySurvival in cancer is continuously improving due to evolving oncological treatment. Therefore, cardiovascular short-term and long-term side effects gain crucial importance for overall outcome. Cardiotoxicity not only presents as heart failure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cf16f7e669295d00147fabe780119a
https://pubmed.ncbi.nlm.nih.gov/35507087
https://pubmed.ncbi.nlm.nih.gov/35507087
Autor:
Wolfgang-Michael Franz, Moritz Messner, Maximilian Doppelhammer, Andreas Petry, Britta Husse, Marc-Michael Zaruba, Thi Van Pham, Santhosh Kumar Ghadge, Agnes Görlach
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
SDF-1/CXCR4 activation facilitates myocardial repair. Therefore, we aimed to activate the HIF-1α target genes SDF-1 and CXCR4 by dimethyloxalylglycine (DMOG)-induced prolyl-hydroxylase (PH) inhibition to augment CXCR4+ cell recruitment and myocardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93be8f7b3c49346f31e2ca35173dd086
https://doi.org/10.1007/s00109-017-1543-3
https://doi.org/10.1007/s00109-017-1543-3