Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marc Mejias"'
Publikováno v:
Current Tissue Microenvironment Reports. 1:121-129
This review provides an overview of the different aspects involved in the crosstalk between fibrogenesis, angiogenesis, and inflammation, contributing to liver disease progression. Fibrosis, characterized by abnormal and excessive deposition of extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f32b174aea4a56bd258ac04ed424d716
https://doi.org/10.1007/s43152-020-00013-w
https://doi.org/10.1007/s43152-020-00013-w
Autor:
Anna Manzano, Salvador Naranjo-Suarez, Marta Ramirez, Raúl Méndez, Mercedes Fernandez, Javier Gallego, Clara Suñer, Marc Mejias, Ramon Bartrons, Nuria Pell
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
BACKGROUND & AIMS: We investigated mechanisms of hepatic stellate cell (HSC) activation, which contributes to liver fibrogenesis. We aimed to determine whether activated HSCs increase glycolysis, which is regulated by 6-phosphofructo-2-kinase/fructos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4274daceadb409dad750faaf3fa80ba
http://hdl.handle.net/2445/176855
http://hdl.handle.net/2445/176855
Publikováno v:
Advances in experimental medicine and biology. 1122
This review chapter describes the current knowledge about the nature of pericytes in the gut, their interaction with endothelial cells in blood vessels, and their pathophysiological functions in the setting of chronic liver disease. In particular, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df74493f70bd9035c55ca10e18c3bcc3
https://pubmed.ncbi.nlm.nih.gov/30937864
https://pubmed.ncbi.nlm.nih.gov/30937864
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030110925
This review chapter describes the current knowledge about the nature of pericytes in the gut, their interaction with endothelial cells in blood vessels, and their pathophysiological functions in the setting of chronic liver disease. In particular, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73a767f07a5612e5b3ee0919021a390f
https://doi.org/10.1007/978-3-030-11093-2_5
https://doi.org/10.1007/978-3-030-11093-2_5
Autor:
Marc Mejias, Marta Ramirez, Mercedes Fernandez, Alba Barrachina-Catala, Ester Garcia-Pras, Nuria Pell, Salvador Naranjo-Suarez, Javier Gallego
Publikováno v:
Current Hepatology Reports. 15:199-207
Chronic liver diseases, including hepatic cirrhosis, chronic hepatitis, alcoholic liver disease, and hepatocellular carcinoma, are one of the commonest causes of death and liver transplantation in adults worldwide. They are accompanied by profound di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c6d81e7619cfad8a3ec7a0666ce885f
https://doi.org/10.1007/s11901-016-0306-x
https://doi.org/10.1007/s11901-016-0306-x
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Development of portosystemic collateral vessels and gastroesophageal varices is responsible for the most serious clinical consequences of portal hypertension, but effective clinical therapies are limited. Here we developed and investigated the therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca983531ba91670d5773fff2b95bc7b
http://europepmc.org/articles/PMC5665956
http://europepmc.org/articles/PMC5665956
Autor:
Marc Mejias, Ester Garcia-Pras, Laura Coch, Jaime Bosch, Javier Gallego, Mercedes Fernandez, Raúl Méndez, Annalisa Berzigotti
Publikováno v:
Hepatology. 60:633-647
Pathological angiogenesis represents a critical hallmark for chronic liver diseases. Understanding the mechanisms regulating angiogenesis is essential to develop new therapeutic strategies that specifically target pathological angiogenesis without af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223ab65dabc0e11104121d0f84030384
https://doi.org/10.1002/hep.26995
https://doi.org/10.1002/hep.26995
Autor:
Jaime Bosch, Javier Gallego, Ester Garcia-Pras, Marc Mejias, Laura Coch, Mercedes Fernandez, Annalisa Berzigotti
Publikováno v:
Gut. 64:657-666
Objective Antiangiogenic strategies have been proposed as a promising new approach for the therapy of portal hypertension and chronic liver disease. Pigment epithelium-derived factor (PEDF) is a powerful endogenous angiogenesis inhibitor whose role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ead4ce1c0e50787ccc24688ee912800
https://doi.org/10.1136/gutjnl-2014-307138
https://doi.org/10.1136/gutjnl-2014-307138
Autor:
Mercedes Fernandez, Annalisa Berzigotti, Ester Garcia-Pras, Carolina Tiani, Andrea De Gottardi, Marc Mejias, Jaime Bosch
Publikováno v:
Journal of Hepatology. 50:296-305
Background/Aims Angiogenesis is a pathological hallmark of portal hypertension. Although VEGF is considered to be the most important proangiogenic factor in neoangiogenesis, this process requires the coordinated action of a variety of factors. Identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b4128b77e396db1e3f76e17b1c9133
https://doi.org/10.1016/j.jhep.2008.09.019
https://doi.org/10.1016/j.jhep.2008.09.019
Publikováno v:
Hepatology. 49:1245-1256
Portal hypertension, the most important complication in patients with cirrhosis of the liver, is a serious and life-threatening disease for which there are few therapeutic options. Because angiogenesis is a pathological hallmark of portal hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea5aa6eaa9a66306218774005e0faac
https://doi.org/10.1002/hep.22758
https://doi.org/10.1002/hep.22758