Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Marc Martinez Llordella"'
Autor:
Trishan Vaikunthanathan, Emmanuelle Landmann, Diana Marin Correa, Marco Romano, Silvia Cellone Trevelin, Qi Peng, Elena Crespo, Mauro Corrado, Juan-José Lozano, Erika L. Pearce, Elena Perpinan, Anna Zoccarato, Leonard Siew, Joy Edwards-Hicks, Reenam Khan, Nguyet-Thin Luu, Mark R. Thursz, Philip N. Newsome, Marc Martinez-Llordella, Naina Shah, Robert I. Lechler, Ajay M. Shah, Alberto Sanchez-Fueyo, Giovanna Lombardi, Niloufar Safinia
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104778- (2023)
Summary: Background: Dysregulated inflammatory responses and oxidative stress are key pathogenic drivers of chronic inflammatory diseases such as liver cirrhosis (LC). Regulatory T cells (Tregs) are essential to prevent excessive immune activation an
Externí odkaz:
https://doaj.org/article/2057022316c44f44b2bce7e9345fbc6f
Autor:
Ada S. Kurt, Karoline Strobl, Paula Ruiz, Gabriel Osborn, Tonika Chester, Lauren Dawson, Karsten M. Warwas, Elizabeth H. Grey, Sotiris Mastoridis, Elisavet Kodela, Niloufar Safinia, Alberto Sanchez-Fueyo, Marc Martinez-Llordella
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD4+CD25+Foxp3+ Tregs are known to acquire tissue-specific features and exert cytoprotective and regenerative functions. The extent to which this applies to liver-resident Tregs is unknown. In this study, we aimed to explore the phenotypic and functi
Externí odkaz:
https://doaj.org/article/4cd7f122501947eea57086af271de87e
Autor:
Anja ten Brinke, Marc Martinez-Llordella, Nathalie Cools, Catharien M. U. Hilkens, S. Marieke van Ham, Birgit Sawitzki, Edward K. Geissler, Giovanna Lombardi, Piotr Trzonkowski, Eva Martinez-Caceres
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been
Externí odkaz:
https://doaj.org/article/4ea85f0db52c429088b49109d293dd81
Autor:
Sotiris Mastoridis, Vishal Patel, Sofia Christakoudi, Juan Jose Lozano, Siamak Salehi, Ada Kurt, Cathleen Grossart, Elisavet Kodela, Marc Martinez‐Llordella, Alberto Sanchez‐Fueyo
Publikováno v:
Hepatology Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e3e4097c5fb3def5c2092508eb6c06
https://doi.org/10.1111/hepr.13909
https://doi.org/10.1111/hepr.13909
Autor:
Sotiris Mastoridis, Giuliana Minani Bertolino, Gavin Whitehouse, Francesco Dazzi, Alberto Sanchez-Fueyo, Marc Martinez-Llordella
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Extracellular vesicles (EVs) are responsible for a multitude of physiological functions, including immunomodulation. A heterogenous mixture of small EV (sEV) subsets, including putative exosomes, is derived when commonly used “exosome” isolation
Externí odkaz:
https://doaj.org/article/8eea0063488d493da433fb9f6d761a31
Autor:
Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medi
Externí odkaz:
https://doaj.org/article/6e6307c0ff3e4a65bfd0edfff5a979c4
Autor:
Kate Childs, Elisavet Kodela, Marc Martinez-Llordella, Maria-Carlota Londoño, Gavin Whitehouse, Alberto Sanchez-Fueyo, Elliot Merritt
Publikováno v:
American Journal of Transplantation. 21:247-257
Virus-induced heterologous immunity is considered a barrier to transplantation tolerance. Yet, hepatitis C (HCV)-infected liver transplant (LT) patients occasionally achieve operational tolerance. We investigated the mechanisms through which HCV infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f007d376fdd74c5599f402f7ce9bd4df
https://doi.org/10.1111/ajt.16134
https://doi.org/10.1111/ajt.16134
Autor:
Victoria T. Kronsten, Charlotte A. Woodhouse, Ane Zamalloa, Tiong Yeng Lim, Lindsey A. Edwards, Marc Martinez-Llordella, Alberto Sanchez-Fueyo, Debbie L. Shawcross
Publikováno v:
Kronsten, V T, Woodhouse, C A, Zamalloa, A, Lim, T Y, Edwards, L A, Martinez-Llordella, M, Sanchez-Fueyo, A & Shawcross, D L 2022, ' Exaggerated inflammatory response to bacterial products in decompensated cirrhotic patients is orchestrated by interferons IL-6 and IL-8 ', American journal of physiology. Gastrointestinal and liver physiology, vol. 322, no. 5, pp. G489-G499 . https://doi.org/10.1152/ajpgi.00012.2022
Cirrhosis-associated immune dysfunction (CAID) contributes to disease progression and organ failure development. We interrogated immune system function in nonseptic compensated and decompensated cirrhotic patients using the TruCulture whole blood sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffcf1047048cdad71c7f6d83156f1c0
https://kclpure.kcl.ac.uk/en/publications/4bd38ea7-b29b-4f49-b3a3-d1d3e0662966
https://kclpure.kcl.ac.uk/en/publications/4bd38ea7-b29b-4f49-b3a3-d1d3e0662966
Publikováno v:
World Journal of Transplantation
Extracellular vesicles (EVs) are a heterogenous group of nanosized, membrane-bound particles which are released by most cell types. They are known to play an essential role in cellular communication by way of their varied cargo which includes selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa5d2f06b9589d959a016fa00c3545e
https://doi.org/10.5500/wjt.v10.i11.330
https://doi.org/10.5500/wjt.v10.i11.330
Autor:
Juan José Lozano, Linda Ariza-McNaughton, Jonathan M. Irish, Syed A Mian, Benedetta Costantini, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Thanos P. Mourikis, Shok Ping Lim, Pilar Perez Abellan, Giovanni A M Povoleri, Ghulam J. Mufti, Susanne Heck, Giovanna Lombardi, Ander Abarrategi, Shreyans Gandhi, Marc Martinez Llordella, Rita Antunes Dos Reis
Publikováno v:
Blood. 136:885-897
Idiopathic aplastic anemia (AA) has 2 key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T-cells (Tregs) deficiency. We have previously demonstrated reduction in a specific subpopulation of Treg in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55ae0d92bc89d6a0015a27e7bff1ccb
https://doi.org/10.1182/blood.2019001347
https://doi.org/10.1182/blood.2019001347