Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marc Majora"'
Autor:
Karin Fehsel, Marie-Luise Bouvier, Loredana Capobianco, Paola Lunetti, Bianca Klein, Marko Oldiges, Marc Majora, Stefan Löffler
Publikováno v:
Cells, Vol 13, Iss 9, p 762 (2024)
The antipsychotic drug clozapine demonstrates superior efficacy in treatment-resistant schizophrenia, but its intracellular mode of action is not completely understood. Here, we analysed the effects of clozapine (2.5–20 µM) on metabolic fluxes, ce
Externí odkaz:
https://doaj.org/article/b7043f18258d4c7b8a1c3fe0c3ddc3ba
Autor:
Ingo Uthe, Maren Knechten, Natascia Ventura, Kevin Sondenheimer, Charlotte Esser, Marc Majora, Alfonso Schiavi, Jean Krutmann
Publikováno v:
Science translational medicine. 10(456)
Cockayne syndrome (CS), a hereditary form of premature aging predominantly caused by mutations in the csb gene, affects multiple organs including skin where it manifests with hypersensitivity toward ultraviolet (UV) radiation and loss of subcutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e811153a16bd6025f349b6b531ce1167
https://pubmed.ncbi.nlm.nih.gov/30158153
https://pubmed.ncbi.nlm.nih.gov/30158153
Publikováno v:
Sensors, Vol 24, Iss 5, p 1416 (2024)
This paper presents the design, proof-of-concept implementation, and preliminary performance assessment of an affordable real-time High-Sensitivity (HS) Global Navigation Satellite System (GNSS) receiver. Specifically tailored to capture and track we
Externí odkaz:
https://doaj.org/article/bd403378dc964567938f55ebd0ae635c
Publikováno v:
Journal of Biological Chemistry. 286:18268-18276
UVB irradiation causes characteristic features of skin aging including remodeling of the dermal extracellular matrix. A key feature during this process is the up-regulation of matrix metalloproteinases and cleavage of collagen. Hyaluronic acid (HA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a72cdae11418dcad36804c1748ede255
https://doi.org/10.1074/jbc.m110.201665
https://doi.org/10.1074/jbc.m110.201665
Autor:
Peter Schroeder, Jean Krutmann, Bianca Schuermann, Marc Majora, Tanja Wittkampf, Ekkehard Wilichowski, Susanne Franke, Maren Schneider, Susanne Grether-Beck, Françoise Bernerd
Publikováno v:
The American Journal of Pathology. 175:1019-1029
Deletions within the mitochondrial DNA (mtDNA) are thought to contribute to extrinsic skin aging. To study the translation of mtDNA deletions into functional and structural changes in the skin, we seeded human skin fibroblasts into collagen gels to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c56fbe3befb0bb8097f80ec58a9d499
https://doi.org/10.2353/ajpath.2009.080832
https://doi.org/10.2353/ajpath.2009.080832
Publikováno v:
International Immunopharmacology. 5:1659-1674
T cell maturation into TCRalphabeta(+) or TCRgammadelta(+) cells from common immature CD4(-)CD8(-)(DN) precursors occurs in the thymus, and is controlled through ordered regulation of genes. The aryl hydrocarbon receptor (AHR), a latent cytoplasmic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d286f443a692d07c718be9c3e0560828
https://doi.org/10.1016/j.intimp.2005.02.010
https://doi.org/10.1016/j.intimp.2005.02.010
Publikováno v:
Sensors, Vol 23, Iss 23, p 9483 (2023)
Global navigation satellite system (GNSS) technology is evolving at a rapid pace. The rapid advancement demands rapid prototyping tools to conduct research on new and innovative signals and systems. However, researchers need to deal with the increasi
Externí odkaz:
https://doaj.org/article/b2659937e6e242dd99e25585bba9052d
Publikováno v:
The Journal of biological chemistry. 286(20)
UVB irradiation causes characteristic features of skin aging including remodeling of the dermal extracellular matrix. A key feature during this process is the up-regulation of matrix metalloproteinases and cleavage of collagen. Hyaluronic acid (HA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9d9f97dee9110d6e5f184229d731f99
https://pubmed.ncbi.nlm.nih.gov/21454612
https://pubmed.ncbi.nlm.nih.gov/21454612