Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Marc M Greenberg"'
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192148 (2018)
Oxidative DNA damage and base excision repair (BER) play important roles in modulating trinucleotide repeat (TNR) instability that is associated with human neurodegenerative diseases and cancer. We have reported that BER of base lesions can lead to T
Externí odkaz:
https://doaj.org/article/bd2f798d46a6491e8d72cd5f4fed059a
Publikováno v:
Chemical Research in Toxicology. 36:782-789
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7500b3db13711447ad6438a9173a347
https://doi.org/10.1021/acs.chemrestox.3c00069
https://doi.org/10.1021/acs.chemrestox.3c00069
Autor:
Marco Paolo Jacinto, Marc M. Greenberg
Publikováno v:
Biochemistry. 62:1388-1393
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb7bc09ae0e913c42352980df51b5468
https://doi.org/10.1021/acs.biochem.3c00007
https://doi.org/10.1021/acs.biochem.3c00007
Publikováno v:
Biochemistry. 61(20)
Positively charged N-terminal histone tails play important roles in maintaining the nucleosome (and chromatin) structure and function. Charge alteration, including those imposed by post-translational modifications, impacts chromatin dynamics, protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92e141fecea884e5497e766c2d033977
https://pubmed.ncbi.nlm.nih.gov/36136907
https://pubmed.ncbi.nlm.nih.gov/36136907
Publikováno v:
Biochemistry. 61:2221-2228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ce5cf3039173677572d0df8d7cdb00
https://doi.org/10.1021/acs.biochem.2c00342
https://doi.org/10.1021/acs.biochem.2c00342
Autor:
Matthew Egleston, Linghao Dong, A. Hasan Howlader, Shridhar Bhat, Benjamin Orris, Mario A. Bianchet, Marc M. Greenberg, James T. Stivers
Publikováno v:
ACS Chemical Biology.
This upload contains all of the experimental data and analysis files pertaining to the accepted manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e21ce5cbf4441deeb2e793ac8f378d
https://doi.org/10.1021/acschembio.3c00118
https://doi.org/10.1021/acschembio.3c00118
Autor:
Haihui Peng, Son Vu, Parker Retes, Samuel Ward, Anil Kumar, Michael D. Sevilla, Amitava Adhikary, Marc M. Greenberg
Publikováno v:
The Journal of Organic Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840d8aa10c098868459b855669531cb6
https://doi.org/10.1021/acs.joc.3c00646
https://doi.org/10.1021/acs.joc.3c00646
Publikováno v:
Acc Chem Res
DNA is damaged by various endogenous and exogenous sources, leading to a diverse group of reactive intermediates that yield a complex mixture of products. The initially formed products are often metastable and can react to yield lesions that are more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ac8a69e828b8869d371c6a63d32e40
https://pubmed.ncbi.nlm.nih.gov/35271268
https://pubmed.ncbi.nlm.nih.gov/35271268
Publikováno v:
J Am Chem Soc
Evaluating the significance of various forms of DNA damage is complicated by discoveries that some lesions inactivate repair enzymes or produce more deleterious forms of damage. Histone lysines within nucleosomes react with the commonly produced C4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6981bf534798420ff05c3ac59222ac02
https://doi.org/10.1021/jacs.2c02880
https://doi.org/10.1021/jacs.2c02880
Publikováno v:
Journal of the American Chemical Society. 143:14738-14747
Oxidative stress produces a variety of radicals in DNA, including pyrimidine nucleobase radicals. The nitrogen-centered DNA radical 2'-deoxycytidin-N4-yl radical (dC·) plays a role in DNA damage mediated by one electron oxidants, such as HOCl and io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb35cf8d50268f86936a4d84194f404c
https://doi.org/10.1021/jacs.1c06425
https://doi.org/10.1021/jacs.1c06425