Application of Dried Urine Spots for Non-Targeted Quadrupole Time-of-Flight Drug Screening

Autor: Frederike Stöth, Marie Martin Fabritius, Wolfgang Weinmann, Marc Luginbühl, Stefan Gaugler, Stefan König

Publikováno v: Journal of Analytical Toxicology. 47:332-337

The use of dried urine spots (DUS) can simplify sample handling, shipment and storage when compared to liquid urine samples. To prepare DUS, a small amount of urine is pipetted on a filter paper card. The subsequent drying of the specimen can prevent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94721fad494cf791d66d468e603ffc02
https://doi.org/10.1093/jat/bkad007

Fully automated correction for the hematocrit bias of non-volumetric dried blood spot phosphatidylethanol analysis

Autor: Frederike Stöth, Marc Luginbühl, Stefan Gaugler, Wolfgang Weinmann

Publikováno v: Alcohol. 94:17-23

The quantitative analysis of substances in dried blood spots (DBS) has gained vast popularity in the past decade. The World Anti-Doping Agency (WADA) also recently committed to implementing DBS. Currently, DBS sampling mainly has focused on various v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7d4b3697cc7f53c69dd96e291c6611
https://doi.org/10.1016/j.alcohol.2021.04.002

Fully Automated Optical Hematocrit Measurement from Dried Blood Spots

Autor: Yannick Fischer, Stefan Gaugler, Marc Luginbühl

Publikováno v: Journal of Analytical Toxicology. 46:187-193

The impact of the hematocrit (HCT) on the dried blood spot (DBS)’s spreading area is one of the most important hurdles, which prevents the full acceptance of quantitative microsampling strategies. Several destructive and non-destructive strategies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba6d21c7f290e2d45bfbf94c6adc300
https://doi.org/10.1093/jat/bkaa189

The application of fully automated dried blood spot analysis for liquid chromatography-tandem mass spectrometry using the CAMAG DBS-MS 500 autosampler

Autor: Stefan Gaugler, Marc Luginbühl

Publikováno v: Clinical Biochemistry. 82:33-39

In the past decade, dried blood spot (DBS) sampling has been used increasingly for microsampling in various fields. This is predominantly driven by the significant advantages DBS offers regarding simple sample retrieval and shipment, combined with in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ec8b9fc4232e3d990a2aa99c48b856
https://doi.org/10.1016/j.clinbiochem.2020.02.007

Variation in the Relative Isomer Abundance of Synthetic and Biologically Derived Phosphatidylethanols and Its Consequences for Reliable Quantification

Autor: Reuben S. E. Young, Frederike Stoeth, Stefan Gaugler, Wolfgang Weinmann, Stephen J. Blanksby, Marc Luginbühl

Publikováno v: Luginbühl, Marc; Young, Reuben S E; Stöth, Frederike; Weinmann, Wolfgang; Blanksby, Stephen J; Gaugler, Stefan (2021). Variation in the relative isomer abundance of synthetic and biologically derived phosphatidylethanols and its consequences for reliable quantification. Journal of analytical toxicology, 45(1), pp. 76-83. Oxford University Press 10.1093/jat/bkaa034

Phosphatidylethanol (PEth) in human blood samples is a marker for alcohol usage. Typically, PEth is detected by reversed-phase liquid chromatography coupled with negative ion tandem mass spectrometry, investigating the fatty acyl anions released from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fd292fba5c8684aa5f7caff4140305
https://doi.org/10.1093/jat/bkaa034