Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Marc Lombes"'
Autor:
Laurence Dumeige, Mélanie Nehlich, Say Viengchareun, Julie Perrot, Eric Pussard, Marc Lombès, Laetitia Martinerie
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 1, Pp 152-165 (2020)
High blood pressure: Exploring inheritance A propensity towards high blood pressure may be passed down through several generations from adults who were born preterm. People who are born prematurely often suffer from kidney (renal) problems, high bloo
Externí odkaz:
https://doaj.org/article/365e4d27f9cd4d4e98be952ee278defc
Autor:
Sarah Saget, Rong Cong, Lyvianne Decourtye, Marie-Laure Endale, Laetitia Martinerie, Clémence Girardet, Claire Perret, Maud Clemessy, Patricia Leneuve, Laetitia Dinard, Badreddine Mohand Oumoussa, Dominique Farabos, Antonin Lamazière, Marc Lombès, Marthe Moldes, Bruno Fève, David Tregouet, Yves Le Bouc, Laurent Kappeler
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101083- (2020)
Objective: Individuals born with intrauterine growth retardation (IUGR) are more prone to cardio-metabolic diseases as adults, and environmental changes during the perinatal period have been identified as potentially crucial factors. We have studied
Externí odkaz:
https://doaj.org/article/9a97067367eb42078f79e261e8535af8
Autor:
Jérémie Canonica, Min Zhao, Tatiana Favez, Emmanuelle Gelizé, Laurent Jonet, Laura Kowalczuk, Justine Guegan, Damien Le Menuet, Say Viengchareun, Marc Lombès, Eric Pussard, Yvan Arsenijevic, Francine Behar-Cohen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9618 (2021)
Glucocorticoids are amongst the most used drugs to treat retinal diseases of various origins. Yet, the transcriptional regulations induced by glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) activation in retinal pigment epithelium ce
Externí odkaz:
https://doaj.org/article/3eaa15dd4893453a9f19eb65f7cbc9d9
Autor:
Margaux Laulhé, Laurence Dumeige, Thi An Vu, Imene Hani, Eric Pussard, Marc Lombès, Say Viengchareun, Laetitia Martinerie
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5275 (2021)
Sexual dimorphism involves differences between biological sexes that go beyond sexual characteristics. In mammals, differences between sexes have been demonstrated regarding various biological processes, including blood pressure and predisposition to
Externí odkaz:
https://doaj.org/article/d382e1af4ee44f638eaf3db507d7843d
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69616 (2013)
Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only mi
Externí odkaz:
https://doaj.org/article/a9255ab17ae24c32ade14102c14476b2
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A. Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P. Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/82a2395d5f8d4a8fbb72e52719c7436b
Autor:
María Florencia Abascal, Andrés Elia, Michelle Alvarez, Gabriela Pataccini, Gonzalo Sequeira, Marina Riggio, Virginia Figueroa, Caroline A. Lamb, Paola A. Rojas, Eunice Spengler, Paula Martínez‐Vazquez, Javier Burruchaga, Marcos Liguori, Ana Sahores, Victoria Wargon, Alfredo Molinolo, Stephen Hewitt, Marc Lombes, Carol Sartorius, Silvia Inés Vanzulli, Sebastián Giulianelli, Claudia Lanari
Publikováno v:
International journal of cancerREFERENCES. 150(9)
Progesterone receptors (PRs) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, PRA and PRB, and their ratio (PRA/PRB) may be predictive of antiprogestin response. Our aim was to investigate: the impact of the PR iso
Autor:
Géraldine Vitellius, Séverine Trabado, Christine Hoeffel, Jérôme Bouligand, Antoine Bennet, Frederic Castinetti, Bénédicte Decoudier, Anne Guiochon-Mantel, Marc Lombes, Brigitte Delemer, F Amiot-Chapoutot, D Ancelle, F Bertoin, T Brue, P Caron, F Borson-Chazot, S Christin-Maitre, O Chabre, R Dessailloud, B Estour, H Grulet, F Illouz, N Jeandidier, V Kerlan, M Klein, A Penfornis, P Pierre, A Tabarin, P Touraine, M C Vantyghem, J Young
Publikováno v:
European Journal of Endocrinology
European Journal of Endocrinology, BioScientifica, 2018, 178 (4), pp.411-423. ⟨10.1530/EJE-17-1071⟩
European Journal of Endocrinology, BioScientifica, 2018, 178 (4), pp.411-423. ⟨10.1530/EJE-17-1071⟩
Background Recently discovered mutations of NR3C1 gene, encoding for the GR, in patients with glucocorticoid resistance and bilateral adrenal incidentalomas prompted us to investigate whether GR mutations might be associated with adrenal hyperplasia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70dcdb1bcc4e2418bac6738f99a40dc
https://hal.univ-reims.fr/hal-01822592
https://hal.univ-reims.fr/hal-01822592
Autor:
Géraldine, Vitellius, Séverine, Trabado, Christine, Hoeffel, Jérôme, Bouligand, Antoine, Bennet, Frederic, Castinetti, Bénédicte, Decoudier, Anne, Guiochon-Mantel, Marc, Lombes, Brigitte, Delemer
Publikováno v:
European journal of endocrinology. 178(4)
Recently discovered mutations ofThe multicenter French Clinical Research Program (Muta-GR) was set up to determine the prevalence of GR mutations and polymorphisms in patients harboring bilateral adrenal incidentalomas associated with hypertension an
Autor:
Ségolène, Hescot, Larbi, Amazit, Marie, Lhomme, Simon, Travers, Anais, DuBow, Stephanie, Battini, Geoffrey, Boulate, Izzie Jacques, Namer, Anne, Lombes, Anatol, Kontush, Alessio, Imperiale, Eric, Baudin, Marc, Lombes
Publikováno v:
Oncotarget
Mitotane (o,p’DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomi