Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Marc Leach"'
Autor:
John H McDermott, Marc Leach, Dwaipayan Sen, Craig J. Smith, William G. Newman, Philip M. Bath
Publikováno v:
Expert Review of Clinical Pharmacology. 15:811-825
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a3831fa093b20ee6741b32ff5212e9
https://doi.org/10.1080/17512433.2022.2108401
https://doi.org/10.1080/17512433.2022.2108401
Autor:
John H, McDermott, Marc, Leach, Dwaipayan, Sen, Craig J, Smith, William G, Newman, Philip M, Bath
Publikováno v:
Expert review of clinical pharmacology. 15(7)
Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemic attack (TIA). Conversion of clopidogrel to its active metabolite by hepatic cytochrome P450-2C19 (CYP2C19) is essential for the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1b119b95424e375afdab5d7f98e73b4
https://pubmed.ncbi.nlm.nih.gov/35912831
https://pubmed.ncbi.nlm.nih.gov/35912831
Publikováno v:
Clin Med (Lond)
Fluid management is an essential competency for hospital doctors, but previous studies suggest junior clinicians lack the necessary ‘knowledge’ and ‘prescription skills’ to complete this task, resulting in preventable morbidity and mortality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c99a4f4e2d5d05200ca80426389a72
https://doi.org/10.7861/clinmed.2019-0433
https://doi.org/10.7861/clinmed.2019-0433
Publikováno v:
Cancer. 115:2903-2911
BACKGROUND: Acute myeloid leukemia (AML) is associated with a poor prognosis, particularly in older patients. To the authors' knowledge, few population-based studies of AML treatment patterns and outcomes exist to date. METHODS: The authors used the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7429cc8e770d46b2e60157df6ec84bc7
https://doi.org/10.1002/cncr.24373
https://doi.org/10.1002/cncr.24373
Autor:
Neil Fleshner, Ian F. Tannock, Gary Naglie, Padraig Warde, Sarah Duff-Canning, Murray Krahn, Marc Leach, Henriette Breunis, Abbas H. Panju, Angela M. Cheung, George Tomlinson, Shabbir M.H. Alibhai
Publikováno v:
BJU International. 103:753-757
OBJECTIVE To determine whether clinicians discuss bone-specific side-effects with patients on androgen-deprivation therapy (ADT) for prostate cancer, or prescribe lifestyle and pharmacological interventions for low bone mineral density (BMD), as decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf15ea658ccf5b447a183c24aad1ba9
https://doi.org/10.1111/j.1464-410x.2008.08156.x
https://doi.org/10.1111/j.1464-410x.2008.08156.x
Publikováno v:
Cancer. 112:1043-1050
BACKGROUND. Comorbidity is an important consideration in oncology practice, particularly among older patients. Although a variety of comorbidity indices have been employed in research studies, it is unclear whether any one index is preferred. METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4dbbec3989fccfb823e61d42a56c1a
https://doi.org/10.1002/cncr.23269
https://doi.org/10.1002/cncr.23269
Publikováno v:
Cancer. 115(2)
BACKGROUND: Radiotherapy (RT) is used commonly to treat localized prostate cancer, particularly among older men and men with comorbid illnesses. Few population-based studies have reported on the rates of major short-term complications that lead to ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2c15c90c4808cc6ca94f5e879194af
https://pubmed.ncbi.nlm.nih.gov/19025976
https://pubmed.ncbi.nlm.nih.gov/19025976
Levels of sex hormones have limited effect on cognition in older men with or without prostate cancer
Autor:
Murray Krahn, Shabbir M.H. Alibhai, F. Hussain, S. Duff Canning, Ian F. Tannock, Padraig Warde, Neil Fleshner, L. Klotz, Gary Naglie, George Tomlinson, Marc Leach, Henriette Breunis, S. Mahmoud
Publikováno v:
Critical reviews in oncology/hematology. 73(2)
Androgen deprivation therapy is commonly used to treat prostate cancer, but by lowering testosterone levels it may affect cognitive function. However, the relationship between testosterone and cognition remains unclear. We examined the relationship b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c178f61344a8bd428bac9ecd421df84
https://pubmed.ncbi.nlm.nih.gov/19346137
https://pubmed.ncbi.nlm.nih.gov/19346137
Autor:
Joseph Brandwein, Vikas Gupta, Marc Leach, George Tomlinson, Mark D. Minden, Shabbir M.H. Alibhai, Fernando Jose Suarez Saiz
Publikováno v:
Critical reviews in oncology/hematology. 69(2)
Although intensive chemotherapy may improve survival in older people with acute myeloid leukemia (AML) without adverse cytogenetics, its impact on quality of life (QOL) is mixed and most patients complain of fatigue up to 6 months after diagnosis. Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2b9553ee5771c11155823212ae7ae9
https://pubmed.ncbi.nlm.nih.gov/18778950
https://pubmed.ncbi.nlm.nih.gov/18778950
Publikováno v:
The Journal of urology. 180(1)
It remains controversial whether short-term surgical complications after radical prostatectomy can be decreased by increasing surgeon or hospital procedural volume. We determined whether hospital or surgeon volumes impacted various short-term surgica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca5373e02afd0da98d50380b4a1d45a
https://pubmed.ncbi.nlm.nih.gov/18485382
https://pubmed.ncbi.nlm.nih.gov/18485382