Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marc L. Lesnick"'
Publikováno v:
Infection and Immunity. 70:7126-7135
Infection of human macrophages with Salmonella enterica serovar Typhimurium or Salmonella enterica serovar Dublin produces delayed cytotoxicity characterized by cell detachment and associated apoptosis. Using a site-specific mutant in the SpvB active
Autor:
Joshua Fierer, Christopher Belcher, Patricia Hasegawa, Donald G. Guiney, Marc L. Lesnick, Michael Kurth, Stephen J. Libby
Publikováno v:
Infection and Immunity. 70:3290-3294
Salmonella enterica serovar Arizona ( S. enterica subspecies IIIa) is a common Salmonella isolate from reptiles and can cause serious systemic disease in humans. The spv virulence locus, found on large plasmids in Salmonella subspecies I serovars ass
Publikováno v:
Cellular Microbiology. 2:49-58
The pathogenesis of serious systemic Salmonella infections is characterized by survival and proliferation of bacteria inside macrophages. Infection of human monocyte-derived macrophages in vitro with S. typhimurium or S. dublin produces cytopathology
Autor:
Donald G. Guiney, Marc L. Lesnick
Publikováno v:
Clinical immunology (Orlando, Fla.). 114(3)
Many bacterial pathogens produce virulence factors that alter the host cell cytoskeleton to promote infection. Salmonella strains target cellular actin in a carefully orchestrated series of interactions that promote bacterial uptake into host cells a
Publikováno v:
Molecular microbiology. 39(6)
ADP-ribosylating enzymes, such as cholera and diphtheria toxins, are key virulence factors for a variety of extracellular bacterial pathogens but have not been implicated previously during intracellular pathogenesis. Salmonella strains are capable of
Autor:
Marc L. Lesnick, Donald G. Guiney
Publikováno v:
Trends in microbiology. 9(1)
The dramatic clinical manifestations of toxigenic infections such as cholera and diphtheria occur without substantial bacterial invasion. Disease is mediated by the secretion of potent toxins that use ADP-ribosylation as the catalytic mechanism under